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Official EU label nameGlossary entry 22655

POTASSIUM HYDROXIDE

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 6 of 13 indexed market datasets: 11 country records and 0 EU Annex records. Every result and evidence gap is listed below.

6 markets with evidence
Markets checked
13
Markets with evidence
6
Evidence gaps
7
Resolved identifiers
4

A missing local match is not permission, approval or proof of safety. It means no strong identity match was resolved in that indexed dataset.

Resolved substance identity

CAS:1310-58-31310-73-2
EC:215-181-3215-185-5
Ingredient index records:
POTASSIUM HYDROXIDE
Ph. Eur. name: kalii hydroxidum
Cosmetic functions: BUFFERING

Potassium hydroxide

Inventory restriction note: III/15a, 15d

Open full local profile
11 matched or reported names
POTASSIUM HYDROXIDEpotassium hydroxidekalii hydroxidumPotassium hydroxide/sodium hydroxidePotassium hydroxidePotassium or sodium hydroxidePotassium or sodium hydroxide Potassium hydroxide/sodium hydroxide CAS No 1310-58-3/1310-73-2Potassium Hydroxide Potassium Hydroxide CAS No 1310-58-3포타슘하이드록사이드또는 소듐하이드록사이드Potassium hydroxide ( ) (CAS No. 1310-58-3) Sodium hydroxide (CAS No. 1310-73-2) 19Potassium hydroxide ( ) (CAS No. 1310-58-3)

Regulatory evidence in all 13 markets

Open each matched record for its scope, concentration, conditions, warnings and official source version.

Swipe or scroll horizontally to see dataset coverage and next actions.

MarketResultRecordsDatasetMeaning / next action
European Union
EU
No local match0
Complete annex dataset
Regulation (EC) 1223/2009 consolidated to 1 May 2026
No annex match only means that these five annexes did not return a match; CosIng identity data and other EU obligations still need review.
Great Britain
GB
Restricted2Open record 1Open record 2
Complete consolidated annex dataset
GB retained Regulation 1223/2009 schedules, effective 15 August 2026
Review every linked record and exact conditions.
Canada
CA
No local match0
Complete Hotlist snapshot
Health Canada Cosmetic Ingredient Hotlist, 13 August 2025
The Hotlist is an administrative compliance tool, not an exhaustive safety approval list.
New Zealand
NZ
Restricted2Open record 1Open record 2
Complete schedules dataset
Cosmetic Products Group Standard schedules effective 1 January 2026
Review every linked record and exact conditions.
ASEAN
ASEAN
Restricted2Open record 1Open record 2
Complete regional annex dataset
ASEAN Cosmetic Directive annexes 2026-1, 22 June 2026
Review every linked record and exact conditions.
China
CN
No local match0
Complete prohibited catalogues plus official-source workflow
NMPA 2021 banned catalogues plus dynamic IECIC List I/List II system current since 2025
IECIC listing is not blanket approval; absence may require the new cosmetic ingredient route, and restrictions are checked separately.
Japan
JP
No local match0
Complete Standards appendices dataset
MHLW Standards for Cosmetics official English source and Japanese amendments checked for the imported snapshot
The Japanese text and subsequent notices are canonical; no local match is not a product-compliance conclusion.
South Korea
KR
Restricted1Open record 1
Complete current appendix dataset
MFDS Notice 2026-19, effective 18 March 2026
Review every linked record and exact conditions.
United States
US
No local match0
Complete enumerated federal ingredient rules
eCFR Title 21 issue date 27 August 2026
FDA has no general approved-cosmetic-ingredient catalogue; absence from these sections is not approval or proof of safety.
Australia
AU
No local match0
Complete cosmetic-relevant Poisons Standard subset plus official workflow
Therapeutic Goods (Poisons Standard—June 2026) Instrument 2026
An AICIS Inventory match is not cosmetic approval; no Inventory match can indicate a new, exempted, reported or confidential introduction.
Brazil
BR
No local match0
Complete prohibited dataset plus current restricted-list workflow
ANVISA RDC 1.029/2026 and RDC 1.030/2026, published 15 June 2026
RDC 1.030/2026 amends rather than replaces the prohibited baseline, and the second restricted-list revision was still under consultation in July 2026.
India
IN
Restricted2Open record 1Open record 2
Complete current Part 2 dataset plus official workflow for Parts 1, 3 and 4
Cosmetics Rules 2020 plus current BIS IS 4707 parts (1:2020, 2:2025, 3:2025, 4:2022)
Review every linked record and exact conditions.
Saudi Arabia
SA
Restricted2Open record 1Open record 2
Complete official list index
SFDA live prohibited/restricted lists, snapshot 30 August 2026
Review every linked record and exact conditions.
No market rows match this filter.

Matching market records and conditions

Great Britain

GB retained Regulation 1223/2009 schedules, effective 15 August 2026
Potassium hydroxide/sodium hydroxideRestricted
(a) Nail cuticle solvent · (a) 5% · (a) Contains alkali Avoid contact with eyes Can cause blindness Keep out of reach of children
GB Cosmetics Regulation, Annex III, entry 15a · 2026-08-15
Potassium hydroxideRestricted
Callosity softener/remover · 1,5% · Contains alkali Avoid contact with eyes Keep out of reach of children Read directions for use carefully
GB Cosmetics Regulation, Annex III, entry 15d · 2026-08-15

New Zealand

Cosmetic Products Group Standard schedules effective 1 January 2026
Potassium or sodium hydroxideRestricted
Product scope: (a) Nail cuticle solvent (b) Hair straightener (i) General use (ii) Professional use (c) pH adjuster – depilatories (d) Other uses as pH adjuster · Maximum concentration: (a) 5% by weight* (b)(i) 2% by weight* (b)(ii) 4.5% by weight* · Other limitations: (c) pH va…
Schedule 5, reference 15a, source row 30 · effective-2026-01-01
Potassium hydroxideRestricted
Product scope: Callosity softener/remover · Maximum concentration: 1.5% · Warnings: Contains alkali. Avoid contact with eyes. Keep out of reach of children. Read directions for use carefully.
Schedule 5, reference 15d, source row 34 · effective-2026-01-01

ASEAN

ASEAN Cosmetic Directive annexes 2026-1, 22 June 2026
Potassium or sodium hydroxide Potassium hydroxide/sodium hydroxide CAS No 1310-58-3/1310-73-2Restricted
(a) Nail cuticle solvent (b) Hair straightener 1. General use 2. Professional use (c) pH adjuster for depilatories (d) Other uses as pH adjuster · (a) 5% by weight( 4( (b) 1. 2% by weight( 4( 2. 4.5% by weight( 4( · For other uses of Potassium Hydroxide, see Annex III, 15d. (c) …
ASEAN Annex III, reference 15a · 2026-1
Potassium Hydroxide Potassium Hydroxide CAS No 1310-58-3Restricted
Callosity softener/remover · 1.5% (4) · For other uses of Potassium hydroxide, see Annex III, No 15a. · • Contains alkali • Avoid contact with eyes • Keep out of reach of children • Read directions for use carefully
ASEAN Annex III, reference 15d · 2026-1

South Korea

MFDS Notice 2026-19, effective 18 March 2026
포타슘하이드록사이드또는 소듐하이드록사이드Restricted
?손톱표피 용해 목적일 경우 5%, pH 조정 목적으로 사용되고 최종 제품이 제5조제5항 에 pH기준이 정하여 있지 아니한 경우에도 최종 제품의 pH는 11이하 ?제모제에서 pH조정 목적으로 사용되는 경우 최종 제품의 pH는 12.7이하 · 포타슘하이드록사이드소듐하이드록사이드
화장품 안전기준 등에 관한 규정, 별표 2, record 2-402 · 2026-19

India

Cosmetics Rules 2020 plus current BIS IS 4707 parts (1:2020, 2:2025, 3:2025, 4:2022)
Potassium hydroxide ( ) (CAS No. 1310-58-3) Sodium hydroxide (CAS No. 1310-73-2) 19Restricted
Field of application/use: a)Nail cuticle solvent b)Hair straightener c) Hadjuster for p depilatories d)Other uses as H p adjuster | Maximum authorised concentration: a)5 percent ( ) b) 1)2 percent ( ) 2)4.5 percent ( ) | Other limitations/requirements: 1)General use 2)Profession…
IS 4707 (Part 2):2025 Annex B, entry 14 · IS 4707 (Part 2):2025, fifth revision
Potassium hydroxide ( ) (CAS No. 1310-58-3)Restricted
Field of application/use: Callosity softner/remover 1.5 percent | Maximum authorised concentration: a)Contains alkali | Label conditions/warnings: b)Avoid contact with eyes c)Read directions for use carefully and d)Keep out of reach of children.
IS 4707 (Part 2):2025 Annex B, entry 15a · IS 4707 (Part 2):2025, fifth revision

Chemical identity and properties

PubChem 2D chemical structure for CAS 1310-58-3
CAS 1310-58-3PubChem CID 14797

Potassium Hydroxide

Potassium hydroxide is an alkali metal hydroxide. — ChEBI

IUPAC name
potassium hydroxide
Molecular formula
HKO
Molecular weight
56.106 g/mol
Exact mass
55.96644614 Da
Topological polar surface area
1.0 Ų
Hydrogen-bond donors
1
Hydrogen-bond acceptors
1
Covalent units
2
Defined stereocentres
0

Also known as

Caustic potashPotash lyePotassium hydrateHydroxyde de potassiumPotassaPotasse caustiqueCaustic-potashKali causticum
16 more reported names
Caswell No. 693Cyantek CC 723Potassium hydroxide (K(OH))KaliumhydroxidCCRIS 6569Potassio (idrossido di)Potassium (hydroxyde de)WZH3C48M4TEPA Pesticide Chemical Code 075602INS NO.525INS-525E-525CHEBI:32035KaliumhydroxydeRefChem:6672MIRACLE WATER 3 in 1
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match14797

Attributed physical-property, hazard, environmental and use annotations.

  • Autoignition Temperature: Not flammable (USCG, 1999) Source: CAMEO Chemicals
  • First Aid: (Act quickly]); EYES: flush with water for at least 15 min.; SKIN: flush with water, then rinse with dilute vinegar (acetic acid).; INGESTION: give water and milk. Do NOT induce vomiting. Call physician at once, even when injury seems to be slight. (USCG, 1999) Source: CAMEO Chemicals
  • First Aid: EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.; SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. IMMEDIATELY call a hospital or poison control center even if no symptoms (such as redness or irritation) develop. IMMEDIATELY transport the victim to a hospital for treatment after washing the affected areas.; INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whene Source: CAMEO Chemicals
  • ERG2024, Guide 154 (Potassium hydroxide, solution; Potassium hydroxide, solid): General First Aid:; · Call 911 or emergency medical service.; · Ensure that medical personnel are aware of the material(s) involved, take precautions to protect themselves and avoid contamination.; · Move victim to fresh air if it can be done safely.; · Administer oxygen if breathing is difficult.; · If victim is not breathing:; -- DO NOT perform mouth-to-mouth resuscitation; the victim may have ingested or inhaled the substance.; -- If equipped and pulse detected, wash face and mouth, then give artificial respiration using a proper respiratory medical device (bag-valve mask, pocket mask equipped with a one-way valve or other device).; -- If no pulse detected or no respiratory medical device available, provide continuous compressions. Conduct a pulse check every two minutes or monitor for any signs of spontaneous respirations.; · Remove and isolate contaminated clothing and shoes.; · For minor skin contact, avoid spreading material on unaffected skin.; · In case of contact with substance, remove immediately by flushing skin or eyes with running water for at least 20 minutes.; · For severe burns, immediate medical attention is required.; · Effects of exposure (inhalation, ingestion, Source: Emergency Response Guidebook (ERG)
  • ERG2024, Guide 154 (Potassium hydroxide, solid; Potassium hydroxide, solution): General First Aid:; · Call 911 or emergency medical service.; · Ensure that medical personnel are aware of the material(s) involved, take precautions to protect themselves and avoid contamination.; · Move victim to fresh air if it can be done safely.; · Administer oxygen if breathing is difficult.; · If victim is not breathing:; -- DO NOT perform mouth-to-mouth resuscitation; the victim may have ingested or inhaled the substance.; -- If equipped and pulse detected, wash face and mouth, then give artificial respiration using a proper respiratory medical device (bag-valve mask, pocket mask equipped with a one-way valve or other device).; -- If no pulse detected or no respiratory medical device available, provide continuous compressions. Conduct a pulse check every two minutes or monitor for any signs of spontaneous respirations.; · Remove and isolate contaminated clothing and shoes.; · For minor skin contact, avoid spreading material on unaffected skin.; · In case of contact with substance, remove immediately by flushing skin or eyes with running water for at least 20 minutes.; · For severe burns, immediate medical attention is required.; · Effects of exposure (inhalation, ingestion, Source: Emergency Response Guidebook (ERG)
  • ERG2024, Guide 154 (Caustic potash, solution; Caustic potash, solid): General First Aid:; · Call 911 or emergency medical service.; · Ensure that medical personnel are aware of the material(s) involved, take precautions to protect themselves and avoid contamination.; · Move victim to fresh air if it can be done safely.; · Administer oxygen if breathing is difficult.; · If victim is not breathing:; -- DO NOT perform mouth-to-mouth resuscitation; the victim may have ingested or inhaled the substance.; -- If equipped and pulse detected, wash face and mouth, then give artificial respiration using a proper respiratory medical device (bag-valve mask, pocket mask equipped with a one-way valve or other device).; -- If no pulse detected or no respiratory medical device available, provide continuous compressions. Conduct a pulse check every two minutes or monitor for any signs of spontaneous respirations.; · Remove and isolate contaminated clothing and shoes.; · For minor skin contact, avoid spreading material on unaffected skin.; · In case of contact with substance, remove immediately by flushing skin or eyes with running water for at least 20 minutes.; · For severe burns, immediate medical attention is required.; · Effects of exposure (inhalation, ingestion, Source: Emergency Response Guidebook (ERG)
  • First Aid: (General first aid procedures); Eye: Irrigate immediately - If this chemical contacts the eyes, immediately wash (irrigate) the eyes with large amounts of water, occasionally lifting the lower and upper lids. Get medical attention immediately.; Skin: Water flush immediately - If this chemical contacts the skin, immediately flush the contaminated skin with water. If this chemical penetrates the clothing, immediately remove the clothing and flush the skin with water. Get medical attention promptly.; Breathing: Respiratory support; Swallow: Medical attention immediately - If this chemical has been swallowed, get medical attention immediately. Source: The National Institute for Occupational Safety and Health (NIOSH)
  • Signal: Danger Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • GHS Hazard Statements: H302: Harmful if swallowed [Warning Acute toxicity, oral]; H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation] Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • Precautionary Statement Codes: P260, P264, P270, P280, P301+P317, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P321, P330, P363, P405, and P501 (click each P-code to see the statement) Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • Note: This chemical does not meet GHS hazard criteria for < 0.1% (3 of 4709) of reports. Source: European Chemicals Agency (ECHA)
  • Signal: Danger Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H290 (20.9%): May be corrosive to metals [Warning Corrosive to Metals]; H302 (96.1%): Harmful if swallowed [Warning Acute toxicity, oral]; H314 (99.4%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]; H318 (24.7%): Causes serious eye damage [Danger Serious eye damage/eye irritation] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P234, P260, P264, P264+P265, P270, P280, P301+P317, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P321, P330, P363, P390, P405, P406, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 4709 reports by companies from 79 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Reported as not meeting GHS hazard criteria per 3 of 4709 reports by companies.; There are 78 notifications provided by 4706 of 4709 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • Signal: Danger Source: NITE-CMC
  • GHS Hazard Statements: H301: Toxic if swallowed [Danger Acute toxicity, oral]; H304: May be fatal if swallowed and enters airways [Danger Aspiration hazard]; H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]; H318: Causes serious eye damage [Danger Serious eye damage/eye irritation]; H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure]; H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure] Source: NITE-CMC
  • Precautionary Statement Codes: P260, P264, P264+P265, P270, P280, P301+P316, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P308+P316, P316, P317, P319, P321, P330, P331, P363, P405, and P501 (click each P-code to see the statement) Source: NITE-CMC
  • GHS Hazard Statements: H301: Toxic if swallowed [Danger Acute toxicity, oral]; H304: May be fatal if swallowed and enters airways [Danger Aspiration hazard]; H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]; H318: Causes serious eye damage [Danger Serious eye damage/eye irritation]; H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure] Source: NITE-CMC
  • Cosmetic Ingredient Review Conclusion: The CIR Expert Panel concluded that ... Potassium Hydroxide is safe in hair straighteners and depilatories under conditions of recommended use; users should minimize skin contact. These ingredients are safe for all other present practices of use and concentration described in this safety assessment when formulated to be nonirritating. Source: Cosmetic Ingredient Review (CIR)
  • Cosmetic Ingredient Review Finding(s): Safe for use in cosmetics, with qualifications Source: Cosmetic Ingredient Review (CIR)
  • Toxicity Summary: IDENTIFICATION AND USE: Potassium hydroxide (KOH) is commercialized as a solid or as solutions with varying concentrations. It is used in soap manufacture; drain and pipeline cleaners; bleaching agents; manufacture of potassium carbonate and tetrapotassium pyrophosphate, an electrolyte in alkaline storage batteries and some fuel cells, absorbent for carbon dioxide and hydrogen sulfide; dyestuffs; liquid fertilizers; food additive; herbicides; electroplating; mercerizing; and paint removers. HUMAN EXPOSURE AND TOXICITY: Potassium hydroxide causes direct local effects on the skin, eyes and gastrointestinal tract after direct exposure. If KOH aerosols/mists occur, they will cause direct local effects on respiratory tract. Solutions with concentrations higher than 2% are corrosive, while concentrations of about 0.5 to about 2.0 % are irritating. The irritant effects are reported as coughing, wheezing, conjunctivitis, tearing, and irritation. Children may be accidentally exposed to commercial cleaning products. In a retrospective clinical study with 168 children after alkaline substance ingestion, 9 children (5.3%) developed gastric outlet obstruction. The fatal complications from an al Source: Hazardous Substances Data Bank (HSDB)
  • Consumer Uses: Solvent; Anti-adhesive/cohesive; Anti-freeze agent; Other; Lubricating agent; Processing aids not otherwise specified; Surfactant (surface active agent); Chemical reaction regulator; Fuel agents; pH regulating agent; Cleaning agent; Ion exchange agent; Not Known or Reasonably Ascertainable; Corrosion inhibitor; Soil amendments (fertilizers); Etching agent; Processing aids, specific to petroleum production; Intermediate Source: EPA Chemical Data Reporting (CDR)
  • Industry Uses: Ion exchange agent; Catalyst; Corrosion inhibitor; Not Known or Reasonably Ascertainable; Soil amendments (fertilizers); Cleaning agent; Absorbent; Oxidizing agent; Surface modifier; Processing aids, specific to petroleum production; Intermediate; Chelating agent; Etching agent; Adhesion/cohesion promoter; Freeze-thaw additive; Lubricating agent; Other; Flavoring and nutrient; Anti-adhesive/cohesive; Anti-freeze agent; Conductive agent; Fuel agents; pH regulating agent; Plating agent; Abrasives; Chemical reaction regulator; Semiconductor and photovoltaic agent; Surfactant (surface active agent); Processing aids not otherwise specified Source: EPA Chemical Data Reporting (CDR)
  • Cosmetic Ingredient Review Link: CIR ingredient: Potassium Hydroxide Source: Cosmetic Ingredient Review (CIR)
  • Sources/Uses: Used to make liquid soaps; it is also used in paint, varnish removers, and drain cleaners; it is used in electroplating, photoengraving, and lithography. [ACGIH] Used as a wet etchant in semiconductor manufacturing at standard concentrations of 50% or 10%; [CSH, p. 46] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
  • Industrial Processes with risk of exposure: Acid and Alkali Cleaning of Metals [Category: Clean]; Electroplating [Category: Plate]; Semiconductor Manufacturing [Category: Industry]; Battery Manufacturing [Category: Industry]; Photographic Processing [Category: Other] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
  • Activities with risk of exposure: Lithography printing [Category: Hobbies] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
  • Uses: For potassium hydroxide (USEPA/OPP Pesticide Code: 075602) there are 0 labels match. /SRP: Not registered for current use in the U.S., but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses./ Source: Hazardous Substances Data Bank (HSDB)
  • Uses: The active ingredient is no longer contained in any registered pesticide products ... "cancelled." Source: Hazardous Substances Data Bank (HSDB)
  • Uses: Manufacturing liquid soap; mordant for wood; absorbing CO2; mercerizing cotton; print and varnish removers; electroplating, photoengraving and lithography; printing inks; in analytical chemistry for alkalimetric titrations; in organic synthesis. Pharmaceutic aid (alkalizer). Source: Hazardous Substances Data Bank (HSDB)
  • Uses: Soap manufacture, bleaching, manufacture of potassium carbonate and tetrapotassium pyrophosphate, electrolyte in alkaline storage batteries and some fuel cells, absorbent for carbon dioxide and hydrogen sulfide, dyestuffs, liquid fertilizers, food additive, herbicides, electroplating, mercerizing, paint removers, reagent. Source: Hazardous Substances Data Bank (HSDB)
  • Uses: For more Uses (Complete) data for POTASSIUM HYDROXIDE (10 total), please visit the HSDB record page. Source: Hazardous Substances Data Bank (HSDB)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 1310-73-2
CAS 1310-73-2PubChem CID 14798

Sodium Hydroxide

IUPAC name
sodium hydroxide
Molecular formula
HNaO
Molecular weight
39.997 g/mol
Exact mass
39.99250893 Da
Topological polar surface area
1.0 Ų
Hydrogen-bond donors
1
Hydrogen-bond acceptors
1
Covalent units
2
Defined stereocentres
0

Also known as

Caustic sodaSodium hydrateAetznatronSoda lyeWhite causticSoda, causticNatriumhydroxidRohrputz
16 more reported names
PlungCollo-GrillreinCollo-TapettaFuers RohrRohrreiniger RofixHydroxyde de sodiumSodium hydroxide (Na(OH))NatriumhydroxydeSoda, hydrateSodium hydroxide dimerNatrium causticumSoda, kaustischeLewis-red devil lyeSodio(idrossido di)Sodium hydroxide (Na2(OH)2)Stamperprep
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match14798

Attributed physical-property, hazard, environmental and use annotations.

  • Autoignition Temperature: Not flammable (USCG, 1999) Source: CAMEO Chemicals
  • First Aid: (Act quickly); EYES: flush with water at once for at least 15 min.; SKIN: flush with water, then rinse with dilute vinegar (acetic acid).; INGESTION: give water and milk. Do NOT induce vomiting. Call physician at once, even when injury seems to be slight. (USCG, 1999) Source: CAMEO Chemicals
  • First Aid: Excerpt from NIOSH Pocket Guide for Sodium hydroxide:; Eye: IRRIGATE IMMEDIATELY - If this chemical contacts the eyes, immediately wash (irrigate) the eyes with large amounts of water, occasionally lifting the lower and upper lids. Get medical attention immediately.; Skin: WATER FLUSH IMMEDIATELY - If this chemical contacts the skin, immediately flush the contaminated skin with water. If this chemical penetrates the clothing, immediately remove the clothing and flush the skin with water. Get medical attention promptly.; Breathing: RESPIRATORY SUPPORT - If a person breathes large amounts of this chemical, move the exposed person to fresh air at once. If breathing has stopped, perform artificial respiration. Keep the affected person warm and at rest. Get medical attention as soon as possible.; Swallow: MEDICAL ATTENTION IMMEDIATELY - If this chemical has been swallowed, get medical attention immediately. (NIOSH, 2024) Source: CAMEO Chemicals
  • ERG2024, Guide 154 (Sodium hydroxide, solution; Sodium hydroxide, solid): General First Aid:; · Call 911 or emergency medical service.; · Ensure that medical personnel are aware of the material(s) involved, take precautions to protect themselves and avoid contamination.; · Move victim to fresh air if it can be done safely.; · Administer oxygen if breathing is difficult.; · If victim is not breathing:; -- DO NOT perform mouth-to-mouth resuscitation; the victim may have ingested or inhaled the substance.; -- If equipped and pulse detected, wash face and mouth, then give artificial respiration using a proper respiratory medical device (bag-valve mask, pocket mask equipped with a one-way valve or other device).; -- If no pulse detected or no respiratory medical device available, provide continuous compressions. Conduct a pulse check every two minutes or monitor for any signs of spontaneous respirations.; · Remove and isolate contaminated clothing and shoes.; · For minor skin contact, avoid spreading material on unaffected skin.; · In case of contact with substance, remove immediately by flushing skin or eyes with running water for at least 20 minutes.; · For severe burns, immediate medical attention is required.; · Effects of exposure (inhalation, ingestion, Source: Emergency Response Guidebook (ERG)
  • ERG2024, Guide 154 (Caustic soda, solid; Caustic soda, solution): General First Aid:; · Call 911 or emergency medical service.; · Ensure that medical personnel are aware of the material(s) involved, take precautions to protect themselves and avoid contamination.; · Move victim to fresh air if it can be done safely.; · Administer oxygen if breathing is difficult.; · If victim is not breathing:; -- DO NOT perform mouth-to-mouth resuscitation; the victim may have ingested or inhaled the substance.; -- If equipped and pulse detected, wash face and mouth, then give artificial respiration using a proper respiratory medical device (bag-valve mask, pocket mask equipped with a one-way valve or other device).; -- If no pulse detected or no respiratory medical device available, provide continuous compressions. Conduct a pulse check every two minutes or monitor for any signs of spontaneous respirations.; · Remove and isolate contaminated clothing and shoes.; · For minor skin contact, avoid spreading material on unaffected skin.; · In case of contact with substance, remove immediately by flushing skin or eyes with running water for at least 20 minutes.; · For severe burns, immediate medical attention is required.; · Effects of exposure (inhalation, ingestion, Source: Emergency Response Guidebook (ERG)
  • First Aid: (General first aid procedures); Eye: Irrigate immediately - If this chemical contacts the eyes, immediately wash (irrigate) the eyes with large amounts of water, occasionally lifting the lower and upper lids. Get medical attention immediately.; Skin: Water flush immediately - If this chemical contacts the skin, immediately flush the contaminated skin with water. If this chemical penetrates the clothing, immediately remove the clothing and flush the skin with water. Get medical attention promptly.; Breathing: Respiratory support; Swallow: Medical attention immediately - If this chemical has been swallowed, get medical attention immediately. Source: The National Institute for Occupational Safety and Health (NIOSH)
  • Signal: Danger Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • GHS Hazard Statements: H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation] Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • Precautionary Statement Codes: P260, P264, P280, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P321, P363, P405, and P501 (click each P-code to see the statement) Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • Note: This chemical does not meet GHS hazard criteria for < 0.1% (4 of 6949) of reports. Source: European Chemicals Agency (ECHA)
  • Signal: Danger Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H290 (47.5%): May be corrosive to metals [Warning Corrosive to Metals]; H314 (> 99.9%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]; H315 (36.5%): Causes skin irritation [Warning Skin corrosion/irritation]; H318 (44.1%): Causes serious eye damage [Danger Serious eye damage/eye irritation]; H319 (36.6%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P234, P260, P264, P264+P265, P280, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P351+P338, P305+P354+P338, P316, P317, P321, P332+P317, P337+P317, P362+P364, P363, P390, P405, P406, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 6949 reports by companies from 80 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Reported as not meeting GHS hazard criteria per 4 of 6949 reports by companies.; There are 79 notifications provided by 6945 of 6949 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H290 (100%): May be corrosive to metals [Warning Corrosive to Metals]; H314 (100%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]; H318 (100%): Causes serious eye damage [Danger Serious eye damage/eye irritation] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P234, P260, P264, P264+P265, P280, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P321, P363, P390, P405, P406, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 2 reports by companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • Signal: Danger Source: NITE-CMC
  • NFPA Health Rating: 3 - Materials that, under emergency conditions, can cause serious or permanent injury. Source: Hazardous Substances Data Bank (HSDB)
  • NFPA Fire Rating: 0 - Materials that will not burn under typical fire conditions, including intrinsically noncombustible materials such as concrete, stone, and sand. Source: Hazardous Substances Data Bank (HSDB)
  • NFPA Instability Rating: 1 - Materials that in themselves are normally stable but that can become unstable at elevated temperatures and pressures. Source: Hazardous Substances Data Bank (HSDB)
  • Cosmetic Ingredient Review Conclusion: The CIR Expert Panel concluded that ... Sodium Hydroxide is safe in hair straighteners and depilatories under conditions of recommended use; users should minimize skin contact. These ingredients are safe for all other present practices of use and concentration described in this safety assessment when formulated to be nonirritating. Source: Cosmetic Ingredient Review (CIR)
  • Cosmetic Ingredient Review Finding(s): Safe for use in cosmetics, with qualifications Source: Cosmetic Ingredient Review (CIR)
  • Environmental Fate: AQUATIC FATE: In the case of a solid, anhydrous sodium hydroxide spill on soil, ground water pollution will occur if precipitation occurs prior to clean up. Precipitation will dissolve some of the solid (with much heat given off) and create an aqueous solution of sodium hydroxide, which then would be able to infiltrate the soil. However, prediction of the concentration and properties of the solution produced would be difficult. Source: Hazardous Substances Data Bank (HSDB)
  • Consumer Uses: Adhesion/cohesion promoter; Etching agent; Flocculating agent; Intermediate; Processing aids, specific to petroleum production; Oxidizing agent; Laboratory chemicals; Dye; Cleaning agent; Plasticizer; Stabilizing agent; Soil amendments (fertilizers); Catalyst; Ion exchange agent; Not Known or Reasonably Ascertainable; Processing aids not otherwise specified; Surfactant (surface active agent); Chemical reaction regulator; Fuel agents; pH regulating agent; Bleaching agent; Solvent; Dispersing agent; Anti-freeze agent; Anti-adhesive/cohesive; Other; Lubricating agent Source: EPA Chemical Data Reporting (CDR)
  • Industry Uses: Soil amendments (fertilizers); Ion exchange agent; Catalyst; Diluent; Not Known or Reasonably Ascertainable; Thickening agent; Corrosion inhibitor; Stabilizing agent; Reducing agent; Cleaning agent; Dye; Softener and conditioner; Adsorbent; Defoamer; Intermediate; Anti-scaling agent; Processing aids, specific to petroleum production; Adhesion/cohesion promoter; Etching agent; Flocculating agent; Chelating agent; Leaching agent; Lubricating agent; Other; Sizing agent; CBI; Swelling agent; Anti-freeze agent; Anti-adhesive/cohesive; Solvent; Fuel agents; pH regulating agent; Antioxidant; Bleaching agent; Chemical reaction regulator; Plating agent; Processing aids, not otherwise listed; Processing aids not otherwise specified Source: EPA Chemical Data Reporting (CDR)
  • Cosmetic Ingredient Review Link: CIR ingredient: Sodium Hydroxide Source: Cosmetic Ingredient Review (CIR)
  • Sources/Uses: Used to neutralize acids, produce sodium salts, hydrolyze fats to make soaps, and precipitate metals; large amounts are used in petroleum refining, rayon production, and rubber reclaiming; [Merck Index # 8627] Also used in metal cleaning, electroplating, processing cotton fabrics, and bleaching; [ATSDR Medical Management] Used in photography (developing bath); [www.ci.tucson.az.us/arthazards/medium.html] In semiconductor manufacturing, sodium hydroxide is used to develop the pattern in the photoresists and also as a wet echant. [CHS, p. 44-5] Caustic soda is used in hide preparation for leather production; [PMID 21938525] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
  • Industrial Processes with risk of exposure: Acid and Alkali Cleaning of Metals [Category: Clean]; Electroplating [Category: Plate]; Petroleum Production and Refining [Category: Industry]; Semiconductor Manufacturing [Category: Industry]; Smelting Copper or Lead [Category: Industry]; Textiles (Fiber & Fabric Manufacturing) [Category: Industry]; Leather Tanning and Processing [Category: Industry]; Photographic Processing [Category: Other]; Textiles (Printing, Dyeing, or Finishing) [Category: Industry]; Metal Extraction and Refining [Category: Industry] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
  • Activities with risk of exposure: Textile arts [Category: Hobbies]; Applying metallic patinas [Category: Hobbies] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
  • Uses: Both oil base and water base fracturing fluids are being used in the fracturing industry. Water base, which includes alcohol-water mixtures and low strength acids, make up the majority of treating fluids. The common chemicals added to these fluids are polymers for viscosity development, crosslinkers for viscosity enhancement, pH control chemicals, gel breakers for polymer degradation following the treatment, surfactants, clay stabilizers, alcohol, bactericides, fluid loss additives and friction reducer. /Hydraulic fracturing/ Source: Hazardous Substances Data Bank (HSDB)
  • Uses: Hydraulic fracturing uses a specially blended liquid which is pumped into a well under extreme pressure causing cracks in rock formations underground. These cracks in the rock then allow oil and natural gas to flow, increasing resource production. ... Chemical Name: Sodium hydroxide; Chemical Purpose: Adjusts the pH of fluid to maintain the effectiveness of other components, such as crosslinkers; Product Function: pH Adjusting agent. Source: Hazardous Substances Data Bank (HSDB)
  • Uses: For sodium hydroxide (USEPA/OPP Pesticide Code: 075603) ACTIVE products with label matches. /SRP: Registered for use in the U.S. but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses./ Source: Hazardous Substances Data Bank (HSDB)
  • Uses: In inorganic chemistry, sodium hydroxide is used in the manufacture of sodium salts, for alkaline ore digestion, and for pH regulation. Source: Hazardous Substances Data Bank (HSDB)
  • Uses: For more Uses (Complete) data for SODIUM HYDROXIDE (16 total), please visit the HSDB record page. Source: Hazardous Substances Data Bank (HSDB)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

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