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Official EU label nameGlossary entry 21829

POLYGLYCERYL-2 TETRAISOSTEARATE

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

0 markets with evidence
Markets checked
13
Markets with evidence
0
Evidence gaps
13
Resolved identifiers
1

Resolved substance identity

CAS:121440-30-0
Ingredient index records:
POLYGLYCERYL-2 TETRAISOSTEARATE
Cosmetic functions: EMULSION STABILISING, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SURFACTANT - CLEANSING

Polyglyceryl-2 tetraisostearate consist of 1,2,3-Propanetriol, homopolymer, isooctadecanoates (1:4) (2 mol glycerol average molar ratio)

Open full local profile
1 matched or reported name
POLYGLYCERYL-2 TETRAISOSTEARATE

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name POLYGLYCERYL-2 TETRAISOSTEARATE.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

Check the markets and their sourcesSearch every market for this name

Chemical identity and properties

PubChem 2D chemical structure for CAS 121440-30-0
CAS 121440-30-0PubChem CID 102523418

Polyglyceryl-2 Tetraisostearate

The CIR Expert Panel concluded that the 274 polyglyceryl fatty acid esters listed below are safe in cosmetics in the present practices of use and concentration described in this safety assessment when formulated to be non-irritating..Polyglyceryl-2 Tetraisostearate... — Cosmetic Ingredient Review (CIR)

IUPAC name
[3-[2,3-bis(16-methylheptadecanoyloxy)propoxy]-2-(16-methylheptadecanoyloxy)propyl] 16-methylheptadecanoate
Molecular formula
C78H150O9
Molecular weight
1232.0 g/mol
Exact mass
1231.12798636 Da
XLogP3
32.3
Topological polar surface area
114.0 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
9
Covalent units
1
Defined stereocentres
0

Also known as

Cithrol PG24ISSalacos 44VCosmol 44VKN8R167SEQS-FACE IS-204 PUNII-KN8R167SEQRefChem:175154PVQZOFSIXYDDHY-UHFFFAOYSA-N
Open full PubChem recordPubChem annotations3D structure image

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match102523418

Attributed physical-property, hazard, environmental and use annotations.

  • Note: This chemical does not meet GHS hazard criteria for 100% (8 of 8) of all reports. Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: Not Classified; Reported as not meeting GHS hazard criteria by 8 of 8 companies. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 8 reports by companies from 1 notifications to the ECHA C&L Inventory.; Reported as not meeting GHS hazard criteria per 8 of 8 reports by companies.; There are 0 notifications provided by 0 of 8 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • Cosmetic Ingredient Review Conclusion: The CIR Expert Panel concluded that the 274 polyglyceryl fatty acid esters listed below are safe in cosmetics in the present practices of use and concentration described in this safety assessment when formulated to be non-irritating..Polyglyceryl-2 Tetraisostearate... Source: Cosmetic Ingredient Review (CIR)
  • Cosmetic Ingredient Review Finding(s): Safe for use in cosmetics, with qualifications Source: Cosmetic Ingredient Review (CIR)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

Each link searches that source for this identity. A link is a research route, not a claim that the source holds an exact record. What each source is, and its legal weight

Cosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortalUS EPA CompTox CTX APIs

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

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