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Official EU label nameGlossary entry 21242

PIPERONYLIC ACID

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

0 markets with evidence
Markets checked
13
Markets with evidence
0
Evidence gaps
13
Resolved identifiers
2

Resolved substance identity

CAS:94-53-1
EC:202-342-8
Ingredient index records:
PIPERONYLIC ACID
Cosmetic functions: SKIN CONDITIONING, SKIN PROTECTING

Methylenedioxybenzoic Acid

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1 matched or reported name
PIPERONYLIC ACID

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name PIPERONYLIC ACID.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 94-53-1
CAS 94-53-1PubChem CID 7196

1,3-Benzodioxole-5-carboxylic acid

Piperonylic acid is a member of the class of benzodioxoles that is 1,3-benzodioxole substituted by a carboxy group at position 5. It is a natural product isolated from several plant species. It is a selective mechanism-based inactivator of the trans-cinnamate 4-hydroxylase enzyme and exhibits antifungal and skin wound healing properties. It has a role as an EC 1.14.14.91 ( trans-cinnamate 4-monooxygenase) inhibitor, an antifungal agent, a vulnerary and a plant metabolite. It is a monocarboxylic acid, an aromatic carboxylic acid and a member of benzodioxoles. It is a conjugate acid of a piperonylate. — ChEBI

IUPAC name
1,3-benzodioxole-5-carboxylic acid
Molecular formula
C8H6O4
Molecular weight
166.13 g/mol
Exact mass
166.02660867 Da
XLogP3
0.4
Topological polar surface area
55.8 Ų
Hydrogen-bond donors
1
Hydrogen-bond acceptors
4
Covalent units
1
Defined stereocentres
0

Also known as

PIPERONYLIC ACIDHeliotropic acid2H-1,3-Benzodioxole-5-Carboxylic Acid3,4-(Methylenedioxy)benzoic acidProtocatechuic acid methylene ether5-Benzodioxolecarboxylic acid3,4-Dioxymethylenebenzoic acidQX3V1NO0KH
16 more reported names
NSC-10072CHEBI:107644RefChem:863626202-342-8Benzo[d][1,3]dioxole-5-carboxylic acid3,4-Methylenedioxybenzoic acidbenzo[1,3]dioxole-5-carboxylic acid3,4-Methylene dioxybenzoic acidBenzoic acid, 3,4-(methylenedioxy)-Spectrum3_001022KBioSS_001644Benzo[d][I,3]dioxole-5-carboxylic acidP04591,3-dioxaindane-5-carboxylic acidPIPERONYLIC ACID-2,2-D2NSC 10072
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External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

Each link searches that source for this identity. A link is a research route, not a claim that the source holds an exact record. What each source is, and its legal weight

Cosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortalUS EPA CompTox CTX APIs

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

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