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Official EU label nameGlossary entry 20706

PHENOLSULFONPHTHALEIN

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

0 markets with evidence
Markets checked
13
Markets with evidence
0
Evidence gaps
13
Resolved identifiers
2

Resolved substance identity

CAS:143-74-8
EC:205-609-7
Ingredient index records:
PHENOLSULFONPHTHALEIN
Cosmetic functions: BUFFERING
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1 matched or reported name
PHENOLSULFONPHTHALEIN

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name PHENOLSULFONPHTHALEIN.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 143-74-8
CAS 143-74-8PubChem CID 4766

Phenol Red

Phenol red is 3H-2,1-Benzoxathiole 1,1-dioxide in which both of the hydrogens at position 3 have been substituted by 4-hydroxyphenyl groups. A pH indicator changing colour from yellow below pH 6.8 to bright pink above pH 8.2, it is commonly used as an indicator in cell cultures and in home swimming pool test kits. It is also used in the (now infrequently performed) phenolsulfonphthalein (PSP) test for estimation of overall blood flow through the kidney. It has a role as a diagnostic agent, an acid-base indicator and a two-colour indicator. It is a member of phenols, a 2,1-benzoxathiole, a sultone and an arenesulfonate ester. — ChEBI

IUPAC name
4-[3-(4-hydroxyphenyl)-1,1-dioxo-2,1lambda6-benzoxathiol-3-yl]phenol
Molecular formula
C19H14O5S
Molecular weight
354.4 g/mol
Exact mass
354.05619472 Da
XLogP3
3.0
Topological polar surface area
92.2 Ų
Hydrogen-bond donors
2
Hydrogen-bond acceptors
5
Covalent units
1
Defined stereocentres
0

Also known as

phenolsulfonphthaleinFenolipunaSulphonthalPSP (indicator)PhenolsulphonphthaleinNSC-10459I6G9Y0J1OJCHEBI:31991
16 more reported names
Phenol, 4,4'-(3H-2,1-benzoxathiol-3-ylidene)bis-, (S,S-dioxide)3,3-bis(4-hydroxyphenyl)-3H-2,1??-benzoxathiole-1,1-dioneRefChem:1728812-(Bis(4-hydroxyphenyl)methyliumyl)benzenesulfonate205-609-7SulfonphthalSulphentalPhenolred3,3-Bis(4-hydroxyphenyl)-3H-benzo[c][1,2]oxathiole 1,1-dioxidePhenolsulfonephthaleinPhenol, 4,4'-(1,1-dioxido-3H-2,1-benzoxathiol-3-ylidene)bis-NSC 10459Phenol red solutionPhenol red indicatorC19H14O5S4,4'-(3H-2,1-Benzoxathiol-3-ylidene)diphenol S,S-dioxide
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

Each link searches that source for this identity. A link is a research route, not a claim that the source holds an exact record. What each source is, and its legal weight

Cosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortalUS EPA CompTox CTX APIs

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

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