Official EU label nameGlossary entry 20425

PENTASILOXANE

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

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Resolved identifiers

Resolved substance identity

CAS:141-63-9

EC:205-492-2

Ingredient index records:

PENTASILOXANE

Cosmetic functions: ANTIFOAMING

Pentasiloxane is the linear siloxane that conforms to the formula.

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1 matched or reported name

PENTASILOXANE

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name PENTASILOXANE.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 141-63-9

CAS 141-63-9PubChem CID 8853

Dodecamethylpentasiloxane

Dodecamethylpentasiloxane is an organosiloxane that is pentasiloxane in which all the hydrogens have been replaced by methyl groups. Metabolite observed in cancer metabolism. It has a role as a human metabolite. — ChEBI

IUPAC name: bis[[dimethyl(trimethylsilyloxy)silyl]oxy]-dimethylsilane

Molecular formula: C12H36O4Si5
Molecular weight: 384.84 g/mol
Exact mass: 384.14599230 Da
Topological polar surface area: 36.9 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 4
Covalent units: 1
Defined stereocentres: 0

Also known as

1,1,1,3,3,5,5,7,7,9,9,9-DodecamethylpentasiloxanePentasiloxane, dodecamethyl-0QDQ2VQ5YJBRN 1792965UNII-0QDQ2VQ5YJEINECS 205-492-2HSDB 8419Pentasiloxane, 1,1,1,3,3,5,5,7,7,9,9,9-dodecamethyl-

16 more reported names

CHEBI:84272EC 205-492-2PENTASILOXANE, DODECAMETHYL4-04-00-04124 (Beilstein Handbook Reference)DODECAMETHYLPENTASILOXANE [MI]Silicone liquidRefChem:1353991,1,1,3,3,5,5,7,7,9,9,9DodecamethylpentasiloxanePentasiloxane, 1,1,1,3,3,5,5,7,7,9,9,9dodecamethyl205-492-2FBZANXDWQAVSTQ-UHFFFAOYSA-NSimethicone Impurity 8dodecamethyl pentasiloxaneDodecamethylpentasiloxane, 97%bis[[dimethyl(trimethylsilyloxy)silyl]oxy]-dimethyl-silanePentasiloxane,1,1,1,3,3,5,5,7,7,9,9,9-dodecamethyl-

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External database identifiers

ChEBI:CHEBI:84272
EPA DTXSID:DTXSID1044803
PubMed:22575024
PubMed:21455817

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

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Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal US EPA CompTox CTX APIs

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

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