Official EU label nameGlossary entry 19012

PANTHENOL

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

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Resolved identifiers

Resolved substance identity

CAS:81-13-016485-10-2

EC:201-327-3240-540-6

Ingredient index records:

PANTHENOL

Ph. Eur. name: dexpanthenolum

Cosmetic functions: ANTISTATIC, HAIR CONDITIONING, SKIN CONDITIONING

Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-, (2R)-; dl-Panthenol

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3 matched or reported names

PANTHENOLdexpanthenoldexpanthenolum

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name PANTHENOL.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 16485-10-2

CAS 16485-10-2PubChem CID 4678

DL-panthenol

Panthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium. Panthenol exists as a racemic mixture containing both the dextrorotatory form (dexpanthenol) and the levorotatory form (levopanthenol). While pantothenic acid is optically active, only the dextrorotatory form ([DB09357]) is biologically active. Dexpanthenol, the active form of panthenol, is enzymatically cleaved to form pantothenic acid (Vitamin B5), which is an essential component of Coenzyme A that acts as a cofactor in many enzymatic reactions that are important for protein metabolism in the epithelium. Due to its good penetration and high local concentrations, dexpanthanol is used in many topical products, such as ointments and lotions for treatment of dermatological conditions to relieve itching or promote healing. Dermatological effects of the topical use of dexpanthenol include increased fibroblast proliferation and accelerated re-epithelialization in wound healing. Furthermore, it acts as a topical protectant, moisturizer, and has demonstrated anti-inflammatory properties. — DrugBank

IUPAC name: 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamide

Molecular formula: C9H19NO4
Molecular weight: 205.25 g/mol
Exact mass: 205.13140809 Da
XLogP3: -0.9
Topological polar surface area: 89.8 Å²
Hydrogen-bond donors: 4
Hydrogen-bond acceptors: 4
Covalent units: 1
Defined stereocentres: 0

Also known as

panthenolDL-PantothenolDL-Pantothenyl alcoholPantenolPanthenolumPantenoloPanthenol, racemic2,4-Dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutyramide

16 more reported names

WV9CM0O67ZRoota Re F TonicNSC-759899Purple TonerELF PermRoota Re V TonicMannitol, PanthenolAAPE Hair AmpouleEyelash Growth SerumRoota Re F for menPanthenol, NiacinamideBREXTEM HRoota Re V for womenRefChem:55808NGF 574H HAIRHyaluronic Acid Facial Serum

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External database identifiers

ChEMBL:CHEMBL1371937
EPA DTXSID:DTXSID3044598
PubMed:22890527
PubMed:22487447
PubMed:22279458
PubMed:22171682
PubMed:21982351
PubMed:21808576
PubMed:21381423
PubMed:21258175
PubMed:21130460
PubMed:20858280
PubMed:20448269
PubMed:20391955

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 81-13-0

CAS 81-13-0PubChem CID 131204

Dexpanthenol

Pantothenol is a monocarboxylic acid amide that is 3,3-dimethylbutanamide substituted by hydroxy groups at positions 2 and 4 and a 3-hydroxypropyl group at the carbomyl nitrogen. It has a role as a cholinergic drug and a provitamin. It is an amino alcohol and a monocarboxylic acid amide. — ChEBI

IUPAC name: (2R)-2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamide

Molecular formula: C9H19NO4
Molecular weight: 205.25 g/mol
Exact mass: 205.13140809 Da
XLogP3: -0.9
Topological polar surface area: 89.8 Å²
Hydrogen-bond donors: 4
Hydrogen-bond acceptors: 4
Covalent units: 1
Defined stereocentres: 1

Also known as

D-PanthenolPantothenolBepanthenD-Pantothenyl alcoholIlopanPantol(+)-PanthenolBepanthene

16 more reported names

BepantolMotilynPanadonThenaltond-PantothenolPantothenyl alcoholPanthodermCozymeZentinicProvitamin BD(+)-PanthenolPantenylSynapanD-P-A InjectionIntrapanUrupan

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External database identifiers

ChEBI:CHEBI:27373
ChEMBL:CHEMBL1200979
EPA DTXSID:DTXSID3022906
PubMed:29968805
PubMed:28503966
PubMed:23120592
PubMed:22759998
PubMed:22546378
PubMed:22529516
PubMed:22427802
PubMed:22395588
PubMed:22379743
PubMed:22360030
PubMed:22347577
PubMed:22320671

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

Each link searches that source for this identity. A link is a research route, not a claim that the source holds an exact record. What each source is, and its legal weight

Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal US EPA CompTox CTX APIs

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

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