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EU cosmetic ingredients, restrictions and safety
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Official EU label nameGlossary entry 18521

OXIDIZED GLUTATHIONE

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

0 markets with evidence
Markets checked
13
Markets with evidence
0
Evidence gaps
13
Resolved identifiers
2

Resolved substance identity

CAS:27025-41-8
EC:248-170-7
Ingredient index records:
OXIDIZED GLUTATHIONE
Cosmetic functions: SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

bi(glutathion-S-yl)

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1 matched or reported name
OXIDIZED GLUTATHIONE

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name OXIDIZED GLUTATHIONE.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 27025-41-8
CAS 27025-41-8PubChem CID 65359

Glutathione Disulfide

Glutathione disulfide is a glutathione derivative and an organic disulfide. It has a role as a mouse metabolite and an Escherichia coli metabolite. It is a conjugate acid of a glutathione disulfide(2-). — ChEBI

IUPAC name
(2S)-2-amino-5-[[(2R)-3-[[(2R)-2-[[(4S)-4-amino-4-carboxybutanoyl]amino]-3-(carboxymethylamino)-3-oxopropyl]disulfanyl]-1-(carboxymethylamino)-1-oxopropan-2-yl]amino]-5-oxopentanoic acid
Molecular formula
C20H32N6O12S2
Molecular weight
612.6 g/mol
Exact mass
612.15196282 Da
XLogP3
-9.1
Topological polar surface area
368.0 Ų
Hydrogen-bond donors
10
Hydrogen-bond acceptors
16
Covalent units
1
Defined stereocentres
4

Also known as

GSSGGlutathione disulphideOxigluthioneGlutathone disulfideOxiglutationaOxiglutationumBis(gamma-glutamyl-L-cysteinylglycine) disulfideULW86O013H
16 more reported names
Disulfide, GlutathioneRefChem:570552-amino-4-((2-((2-(4-amino-4-carboxybutanamido)-2-((carboxymethyl)carbamoyl)ethyl)disulfanyl)-1-((carboxymethyl)carbamoyl)ethyl)carbamoyl)butanoic acidoxiglutationeGlutathione-ssgOxiglutatione [INN]Bi(glutathion-S-yl)Oxiglutationum [INN-Latin]Oxiglutationa [INN-Spanish]CCRIS 780121-24-4N-(N-gamma-Glutamyl-cysteinyl)glycine-(2,2)-disulfideGlutathione oxidized formGlutamine, N,N'-(dithiobis(1-((carboxymethyl)carbamoyl)ethylene))di-, L-Glycine, L-gamma-glutamyl-L-cysteinyl-, (2,2')-disulfideGlutathione EP Impurity C
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External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

Each link searches that source for this identity. A link is a research route, not a claim that the source holds an exact record. What each source is, and its legal weight

Cosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortalUS EPA CompTox CTX APIs

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

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