Official EU label nameGlossary entry 17257

NARIRUTIN

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

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Resolved identifiers

Resolved substance identity

CAS:14259-46-2

EC:238-138-0

Ingredient index records:

NARIRUTIN

Cosmetic functions: ANTIOXIDANT

4H-1-Benzopyran-4-one, 7-[[6-O-(6-deoxy-.alpha.-L-mannopyranosyl)-.beta.-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-, (2S)-,Isonaringin

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1 matched or reported name

NARIRUTIN

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name NARIRUTIN.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 14259-46-2

CAS 14259-46-2PubChem CID 442431

Narirutin

Narirutin is a disaccharide derivative that is (S)-naringenin substituted by a 6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage. It has a role as an antioxidant, a metabolite and an anti-inflammatory agent. It is a member of 4'-hydroxyflavanones, a (2S)-flavan-4-one, a rutinoside, a dihydroxyflavanone and a disaccharide derivative. It is functionally related to a (S)-naringenin. — ChEBI

IUPAC name: (2S)-5-hydroxy-2-(4-hydroxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxy-2,3-dihydrochromen-4-one

Molecular formula: C27H32O14
Molecular weight: 580.5 g/mol
Exact mass: 580.17920569 Da
XLogP3: -1.1
Topological polar surface area: 225.0 Å²
Hydrogen-bond donors: 8
Hydrogen-bond acceptors: 14
Covalent units: 1
Defined stereocentres: 11

Also known as

IsonaringeninIsonaringinNaringenin 7-O-rutinoside06M5EAT0YCCHEBI:28705(2S)-5-hydroxy-2-(4-hydroxyphenyl)-4-oxo-3,4-dihydro-2H-chromen-7-yl 6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosideRefChem:43558238-138-0

16 more reported names

4H-1-Benzopyran-4-one, 7-((6-O-(6-deoxy-alpa-L-mannopyranosyl)-beta-D-glucopyranosyl)oxy)-2,3-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-, (2S)-4H-1-BENZOPYRAN-4-ONE, 7-((6-O-(6-DEOXY-alpha-L-MANNOPYRANOSYL)-beta-D-GLUCOPYRANOSYL)OXY)-2,3-DIHYDRO-5-HYDROXY-2-(4-HYDROXYPHENYL)-, (2S)-Naringenin-7-O-rutinoside(2S)-NarirutinNaringenin 7-beta-rutinosideFEMA No. 2769EINECS 238-138-0UNII-06M5EAT0YC4H-1-Benzopyran-4-one,7-[[6-O-(6-deoxy-a-L-mannopyranosyl)-b-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-, (2S)-Narirutin (Standard)Naringenin-7-rutinosideISONARINGIN [USP-RS]Narirutin, >=98% (HPLC)HY-N0804RHXTFHSYLYXVTHC-AJHDJQPGSA-NHY-N0804

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External database identifiers

ChEBI:CHEBI:28705
ChEMBL:CHEMBL446246
EPA DTXSID:DTXSID30931535
PubMed:22957912
PubMed:22953908
PubMed:22888512
PubMed:22813871
PubMed:22454671
PubMed:22254014
PubMed:22194772
PubMed:22125675
PubMed:21837249
PubMed:21802267
PubMed:21799684
PubMed:21779843

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

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Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal US EPA CompTox CTX APIs

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

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