METHYL SALICYLATE
This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.
Global evidence snapshot
The resolved identity has matching regulatory evidence in 5 of 13 indexed market datasets: 4 country records and 1 EU Annex records. Every result and evidence gap is listed below.
A missing local match is not permission, approval or proof of safety. It means no strong identity match was resolved in that indexed dataset.
Resolved substance identity
methyl 2-hydroxybenzoate
6 matched or reported names
Regulatory evidence in all 13 markets
Open each matched record for its scope, concentration, conditions, warnings and official source version.
Swipe or scroll horizontally to see dataset coverage and next actions.
| Market | Result | Records | Dataset | Meaning / next action |
|---|---|---|---|---|
| European Union EU | Restricted | 1Open record 1 | Complete annex dataset Regulation (EC) 1223/2009 consolidated to 1 May 2026 | Review every linked record and exact conditions. |
| Great Britain GB | Restricted | 1Open record 1 | Complete consolidated annex dataset GB retained Regulation 1223/2009 schedules, effective 15 August 2026 | Review every linked record and exact conditions. |
| Canada CA | Restricted | 1Open record 1 | Complete Hotlist snapshot Health Canada Cosmetic Ingredient Hotlist, 13 August 2025 | Review every linked record and exact conditions. |
| New Zealand NZ | Restricted | 1Open record 1 | Complete schedules dataset Cosmetic Products Group Standard schedules effective 1 January 2026 | Review every linked record and exact conditions. |
| ASEAN ASEAN | No local match | 0 | Complete regional annex dataset ASEAN Cosmetic Directive annexes 2026-1, 22 June 2026 | Regional annex coverage does not replace member-state implementation dates, notifications or national deviations. |
| China CN | No local match | 0 | Complete prohibited catalogues plus official-source workflow NMPA 2021 banned catalogues plus dynamic IECIC List I/List II system current since 2025 | IECIC listing is not blanket approval; absence may require the new cosmetic ingredient route, and restrictions are checked separately. |
| Japan JP | No local match | 0 | Complete Standards appendices dataset MHLW Standards for Cosmetics official English source and Japanese amendments checked for the imported snapshot | The Japanese text and subsequent notices are canonical; no local match is not a product-compliance conclusion. |
| South Korea KR | No local match | 0 | Complete current appendix dataset MFDS Notice 2026-19, effective 18 March 2026 | Korean source wording is canonical and other positive lists/notices may still apply to the formulation. |
| United States US | No local match | 0 | Complete enumerated federal ingredient rules eCFR Title 21 issue date 27 August 2026 | FDA has no general approved-cosmetic-ingredient catalogue; absence from these sections is not approval or proof of safety. |
| Australia AU | No local match | 0 | Complete cosmetic-relevant Poisons Standard subset plus official workflow Therapeutic Goods (Poisons Standard—June 2026) Instrument 2026 | An AICIS Inventory match is not cosmetic approval; no Inventory match can indicate a new, exempted, reported or confidential introduction. |
| Brazil BR | No local match | 0 | Complete prohibited dataset plus current restricted-list workflow ANVISA RDC 1.029/2026 and RDC 1.030/2026, published 15 June 2026 | RDC 1.030/2026 amends rather than replaces the prohibited baseline, and the second restricted-list revision was still under consultation in July 2026. |
| India IN | No local match | 0 | Complete current Part 2 dataset plus official workflow for Parts 1, 3 and 4 Cosmetics Rules 2020 plus current BIS IS 4707 parts (1:2020, 2:2025, 3:2025, 4:2022) | The standards are separate controlled publications; absence from a locally indexed excerpt is not permission. |
| Saudi Arabia SA | Restricted | 1Open record 1 | Complete official list index SFDA live prohibited/restricted lists, snapshot 30 August 2026 | Review every linked record and exact conditions. |
Matching market records and conditions
Great Britain
GB retained Regulation 1223/2009 schedules, effective 15 August 2026Canada
Health Canada Cosmetic Ingredient Hotlist, 13 August 2025New Zealand
Cosmetic Products Group Standard schedules effective 1 January 2026Saudi Arabia
SFDA live prohibited/restricted lists, snapshot 30 August 2026Exact Annex II–VI evidence
METHYL SALICYLATE
Product scope: (a) Leave-on skin products (except face makeup, spray/aerosol body lotion, spray/aerosol deodorant and hydroalcoholic-based fragrances) and leave on hair products (except spray/aerosol products) (b) Face makeup (except lip products, eye makeup and makeup remover) (c) Eye makeup and makeup remover (d) Leave-on hair products (spray/aerosol) (e) Deodorant spray/aerosol (f) Body lotion spray/aerosol (g) Rinse-off skin products (except hand wash) and rinse-off hair products (h) Hand wash (i) Hydroalcoholic-based fragrances (j) Lip products (k) Toothpaste (l) Mouthwash intended for children aged 6–10 years (m) Mouthwash intended for children above 10 years of age and adults (n) Mouth spray
Maximum concentration: (a) 0,06 % (b) 0,05 % (c) 0,002 % (d) 0,009 % (e) 0,003 % (f) 0,04 % (g) 0,06 % (h) 0,6 % (i) 0,6 % (j) 0,03 % (k) 2,52 % (l) 0,1 % (m) 0,6 % (n) 0,65 %
Restrictions: Not to be used in preparations for children under 6 years of age, with the exception of (k) “Toothpaste”. The presence of the substance shall be indicated in the list of ingredients referred to in Article 19(1), point (g), when its concentration exceeds: — 0,001 % in leave-on products — 0,01 % in rinse-off products.
Chemical identity and properties
Methyl Salicylate
- IUPAC name
- methyl 2-hydroxybenzoate
- Molecular formula
- C8H8O3
- Molecular weight
- 152.15 g/mol
- Exact mass
- 152.047344113 Da
- XLogP3
- 2.3
- Topological polar surface area
- 46.5 Ų
- Hydrogen-bond donors
- 1
- Hydrogen-bond acceptors
- 3
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
16 more reported names
External database identifiers
- ChEBI:CHEBI:31832
- ChEMBL:CHEMBL108545
- EPA DTXSID:DTXSID5025659
- PubMed:39159849
- PubMed:36416909
- PubMed:31734321
- PubMed:28826779
- PubMed:27965148
- PubMed:27729775
- PubMed:26973745
- PubMed:26795242
- PubMed:25425092
- PubMed:25411557
- PubMed:24712652
- PubMed:23583298
Evidence from additional scientific databases
NIH PubChem PUG-View
Attributed physical-property, hazard, environmental and use annotations.
- Autoignition Temperature: 847 °F (USCG, 1999) Source: CAMEO Chemicals
- Autoignition Temperature: 850 °F Source: Hazardous Substances Data Bank (HSDB)
- Autoignition Temperature: 450 °C Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Boiling Point: 432 °F at 760 mmHg (NTP, 1992) Source: CAMEO Chemicals
- Boiling Point: 220-224 Source: DrugBank
- Boiling Point: 220-224 °C Source: Hazardous Substances Data Bank (HSDB)
- Boiling Point: 222.00 to 224.00 °C. @ 760.00 mm Hg Source: Human Metabolome Database (HMDB)
- Boiling Point: 223 °C Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Boiling Point: 222 °C Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- Boiling Point: 223.3 °C @760 [mm Hg] Source: PAC Chemical Database, U.S. Department of Energy
- Color/Form: COLORLESS, YELLOWISH OR REDDISH, OILY LIQ Source: Hazardous Substances Data Bank (HSDB)
- Density: 1.174 (USCG, 1999) - Denser than water; will sink Source: CAMEO Chemicals
- Density: 1.184 @ 25 °C/25 °C Source: Hazardous Substances Data Bank (HSDB)
- Density: DENSITY OF NATURAL ESTER IS ABOUT 1.180 Source: Hazardous Substances Data Bank (HSDB)
- Density: Relative density (water = 1): 1.18 Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Density: 1.176-1.185 Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- Density: 1.184 @25 °C Source: PAC Chemical Database, U.S. Department of Energy
- Dissociation Constants: pKa = 9.8 Source: Hazardous Substances Data Bank (HSDB)
- Flash Point: 205 °F (NTP, 1992) Source: CAMEO Chemicals
- Flash Point: 205 °F (96 °C) (Closed cup) Source: Hazardous Substances Data Bank (HSDB)
- Flash Point: 101 °C c.c. Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- LogP: 2.5 Source: DrugBank
- LogP: Log Kow = 2.55 Source: Hazardous Substances Data Bank (HSDB)
- LogP: 2.55 Source: Human Metabolome Database (HMDB)
- LogP: 2.55 Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Melting Point: 16.5 °F (NTP, 1992) Source: CAMEO Chemicals
- Melting Point: -8.6 Source: DrugBank
- Melting Point: -8.6 °C Source: Hazardous Substances Data Bank (HSDB)
- Melting Point: -8.6 °C Source: Human Metabolome Database (HMDB)
- Melting Point: -8 °C Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Melting Point: -8.6 °C Source: PAC Chemical Database, U.S. Department of Energy
- Odor: LIQUID HAVING THE CHARACTERISTIC ODOR OF WINTERGREEN Source: Hazardous Substances Data Bank (HSDB)
- Physical Description: Methyl salicylate appears as colorless yellowish or reddish liquid with odor of wintergreen. (USCG, 1999) Source: CAMEO Chemicals
- Physical Description: CBI; Liquid Source: EPA Chemical Data Reporting (CDR)
- Physical Description: Colorless, yellow, or red liquid with a wintergreen odor; [HSDB] Clear slightly yellow-green liquid; [MSDSonline] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Physical Description: Liquid Source: Human Metabolome Database (HMDB)
- Physical Description: COLOURLESS OR YELLOW-TO-RED OILY LIQUID WITH CHARACTERISTIC ODOUR. Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Physical Description: colourless to yellowish liquid with a characteristic wintergreen odour Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- Refractive Index: INDEX OF REFRACTION: 1.5369 AT 20 °C/D; MAX ABSORPTION: 306 NM (LOG E= 3.64); SADTLER REFERENCE NUMBER: 2238 (IR, PRISM); MAX ABSORPTION (ALC): 238 NM (LOG E= 3.97) Source: Hazardous Substances Data Bank (HSDB)
- Refractive Index: 1.534-1.538 Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- Solubility: less than 1 mg/mL at 66 °F (NTP, 1992) Source: CAMEO Chemicals
- Solubility: Slightly soluble Source: DrugBank
- Solubility: SOL IN CHLOROFORM, ETHER; MISCIBLE WITH ALC, GLACIAL ACETIC ACID Source: Hazardous Substances Data Bank (HSDB)
- Solubility: SOL IN DIETHYL ETHER Source: Hazardous Substances Data Bank (HSDB)
- Solubility: SOLUBLE IN MOST COMMON ORGANIC SOLVENTS Source: Hazardous Substances Data Bank (HSDB)
- Solubility: Sol in water: 0.74%w @ 30 °C Source: Hazardous Substances Data Bank (HSDB)
- Solubility: 0.7 mg/mL at 30 °C Source: Human Metabolome Database (HMDB)
- Solubility: Solubility in water, g/l at 30 °C: 0.74 (very slightly soluble) Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Solubility: slightly soluble in water; soluble in organic solvents, oils Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- Solubility: miscible at room temperature (in ethanol) Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- Vapor Pressure: 0.0975 mmHg at 68 °F ; 1 mmHg at 129 °F (NTP, 1992) Source: CAMEO Chemicals
- Vapor Pressure: 0.03 [mmHg] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Vapor Pressure: Vapor pressure = 0.0343 mm Hg @ 25 °C Source: Hazardous Substances Data Bank (HSDB)
- Vapor Pressure: Vapor pressure, Pa at 20 °C: 13 Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Vapor Pressure: 0.0343 [mm Hg] @25 °C Source: PAC Chemical Database, U.S. Department of Energy
- Viscosity: 1.535 mPa*s at 25 °C Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Carcinogen Classification: No indication of carcinogenicity to humans (not listed by IARC). Source: Toxin and Toxin Target Database (T3DB)
- Exposure Routes: The substance can be absorbed into the body by inhalation, through the skin and by ingestion. Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- First Aid: EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.; SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.; INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) shou Source: CAMEO Chemicals
- Signal: Warning Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
- GHS Hazard Statements: H302: Harmful if swallowed [Warning Acute toxicity, oral]; H317: May cause an allergic skin reaction [Warning Sensitization, Skin]; H361d: Suspected of damaging the unborn child [Warning Reproductive toxicity]; H412: Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard] Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
- Precautionary Statement Codes: P203, P261, P264, P270, P272, P273, P280, P301+P317, P302+P352, P318, P321, P330, P333+P317, P362+P364, P405, and P501 (click each P-code to see the statement) Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
- Note: This chemical does not meet GHS hazard criteria for 0.3% (6 of 2210) of reports. Source: European Chemicals Agency (ECHA)
- Signal: Warning Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: H302 (96.9%): Harmful if swallowed [Warning Acute toxicity, oral] Source: European Chemicals Agency (ECHA)
- Precautionary Statement Codes: P264, P270, P301+P317, P330, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: Aggregated GHS information provided per 2210 reports by companies from 32 notifications to the ECHA C&L Inventory.; Reported as not meeting GHS hazard criteria per 6 of 2210 reports by companies.; There are 31 notifications provided by 2204 of 2210 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- Note: This chemical does not meet GHS hazard criteria for 2.4% (37 of 1530) of reports. Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: H302 (97.5%): Harmful if swallowed [Warning Acute toxicity, oral]; H319 (91.1%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] Source: European Chemicals Agency (ECHA)
- Precautionary Statement Codes: P264, P264+P265, P270, P280, P301+P317, P305+P351+P338, P330, P337+P317, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: Aggregated GHS information provided per 1530 reports by companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Reported as not meeting GHS hazard criteria per 37 of 1530 reports by companies.; There are 9 notifications provided by 1493 of 1530 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- NFPA Health Rating: 1 - Materials that, under emergency conditions, can cause significant irritation. Source: Hazardous Substances Data Bank (HSDB)
- NFPA Fire Rating: 1 - Materials that must be preheated before ignition can occur. Materials require considerable preheating, under all ambient temperature conditions, before ignition and combustion can occur. Source: Hazardous Substances Data Bank (HSDB)
- NFPA Instability Rating: 0 - Materials that in themselves are normally stable, even under fire conditions. Source: Hazardous Substances Data Bank (HSDB)
- Cosmetic Ingredient Review Conclusion: The Panel concluded that the following ingredients are safe in cosmetics in the present practices of use and concentration described in the safety assessment, when formulated to be non-irritating and non-sensitizing, which may be based on a quantitative risk assessment (QRA)...Methyl Salicylate... Source: Cosmetic Ingredient Review (CIR)
- Cosmetic Ingredient Review Finding(s): Safe for use in cosmetics, with qualifications Source: Cosmetic Ingredient Review (CIR)
- Environmental Bioconcentration: The log octanol/water partition coefficient for methyl salicylate is 2.55(1). The BCF estimated from this log Kow using a regression equation is 4 which indicates that the ester will not bioconcentrate in fish(SRC). Source: Hazardous Substances Data Bank (HSDB)
- Environmental Fate: TERRESTRIAL FATE: If released on soil, methyl salicylate would readily leach. It would also be expected to partially volatilize from dry soil and photolyze on the soil surface. Based on the results of sceening tests, it would be expected to readily biodregrade. Chemical hydrolysis may be important in alkaline soil. (SRC) Source: Hazardous Substances Data Bank (HSDB)
- Environmental Fate: AQUATIC FATE: Methyl salicylate is readily biodegradable in screening tests and may be expected to biodegrade in surface waters. Methyl salicylate is expected to hydrolyze in water, the hydrolysis rate increasing with pH. At pH 7.5, its hydrolysis half-life is estimated to be 14.1 days(1,2,SRC). Methyl salicylate will react with singlet oxygen in natural surface waters resulting in a half-life of about 52 hr(3). Methyl salicylate absorbs UV radiation >290 nm and therefore may undergo direct photolysis under environmental conditions. Based on an estimated Henry's Law constant of 9.3X10-7 atm-cu-m/mol(4,5,SRC), a volatilization half-life of 49 days would be expected in a model river(SRC). Source: Hazardous Substances Data Bank (HSDB)
- Environmental Fate: ATMOSPHERIC FATE: Methyl salicylate reacts with photochemically-produced hydroxyl radicals in the atmosphere resulting in an estimated half-life of 1.4 days(1,SRC). It is fairly soluble in water, 7400 mg/L(2) and may be washed out by rain. Source: Hazardous Substances Data Bank (HSDB)
- Consumer Uses: Fragrance; Not Known or Reasonably Ascertainable; Other Source: EPA Chemical Data Reporting (CDR)
- Industry Uses: Not Known or Reasonably Ascertainable; Fragrance; Flavoring and nutrient; Intermediates Source: EPA Chemical Data Reporting (CDR)
- Cosmetic Ingredient Review Link: CIR ingredient: Methyl Salicylate Source: Cosmetic Ingredient Review (CIR)
- Sources/Uses: Used as food flavor (restricted by FDA); [Hawley] Used as flavor, UV-absorber in sunscreens, fragrance, solvent (insecticides, polishes, and inks), antiseptic in oral hygiene products, dye carrier, UV light stabilizer in acrylic resins, and topical analgesic in human and veterinary medicine; [HSDB] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Industrial Processes with risk of exposure: Using Disinfectants or Biocides [Category: Clean] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Uses: OIL: IN FERN AND CYPRESS TYPE PERFUMES & IN TOOTHPASTE Source: Hazardous Substances Data Bank (HSDB)
- Uses: MEDICATION (VET) Source: Hazardous Substances Data Bank (HSDB)
- Uses: MEDICATION Source: Hazardous Substances Data Bank (HSDB)
- Uses: UV-absorber in sunburn lotions; flavor in foods, beverages, pharmaceuticals; odorant Source: Hazardous Substances Data Bank (HSDB)
- Uses: For more Uses (Complete) data for METHYL SALICYLATE (9 total), please visit the HSDB record page. Source: Hazardous Substances Data Bank (HSDB)
Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record
Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.
Additional source coverage and match status
| Source | Result | Checked |
|---|---|---|
| NIH PubChem PUG-View | Exact match | 2026-08-31 |
A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
Additional authoritative substance research
These source-specific lookups can add hazard, toxicology, identity and assessment context. A link is a research route, not a claim that the source contains an exact record.
Cosmetic Ingredient Review safety assessments
Expert Panel conclusions, assessed ingredient groups, use conditions, dates and report documents
Independent expert review considered by FDA; not a government approval or binding market rule
Research this identityFDA Global Substance Registration System
UNII identifiers, preferred names, substance types, codes and public substance relationships
Identity registry only; UNII availability does not imply FDA review or approval
Research this identityILO/WHO International Chemical Safety Cards
Hazards, symptoms, first aid, storage, incompatibilities and physical properties for covered chemicals
International occupational chemical-safety reference; not cosmetic-use approval
Research this identityJapan NITE-CHRIP
Chemical identity, Japanese and foreign legal lists, GHS hazards and exposure-related information
Chemical-management evidence; cosmetic status remains governed by the applicable MHLW standard and market rules
Research this identityNIOSH Pocket Guide to Chemical Hazards
REL, PEL, IDLH, properties, exposure routes, symptoms, target organs, first aid and measurement methods for covered workplace chemicals
US occupational-health guidance and limits; not a cosmetic ingredient decision
Research this identityOECD eChemPortal
Gateway to authority-owned physical-property, fate, ecotoxicity, toxicity, exposure and GHS records
Discovery gateway; each linked authority remains responsible for its data
Research this identityUS EPA CompTox CTX APIs
DTXSID identity, experimental and predicted properties, toxicity, bioactivity, exposure and environmental data
Scientific and computational evidence; predictions must remain labelled and do not determine cosmetic legality
Research this identityContinue the compliance check
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Match the supplier specification, CAS/EC identifiers and composition to this official label name. Similar wording is not proof of chemical equivalence.
2. Review restrictions
Check every exact Annex record shown above, plus CMR, nanomaterial, SCCS and later-amendment requirements that may apply.
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Official source and scope
Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.
Open official Decision