Official EU label nameGlossary entry 16178

MENADIONE

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

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Resolved identifiers

Resolved substance identity

CAS:58-27-5

EC:200-372-6

Ingredient index records:

MENADIONE

Cosmetic functions: FRAGRANCE

1,4-Naphthalenedione, 2-methyl-; Vitamin K3

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2 matched or reported names

MENADIONEmenadione

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name MENADIONE.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 58-27-5

CAS 58-27-5PubChem CID 4055

Menadione

Menadione is a member of the class of 1,4-naphthoquinones that is 1,4-naphthoquinone which is substituted at position 2 by a methyl group. It is used as a nutritional supplement and for the treatment of hypoprothrombinemia. It has a role as an EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor, an antineoplastic agent, an angiogenesis inhibitor, a nutraceutical and a human urinary metabolite. It is a member of 1,4-naphthoquinones and a vitamin K. — ChEBI

IUPAC name: 2-methylnaphthalene-1,4-dione

Molecular formula: C11H8O2
Molecular weight: 172.18 g/mol
Exact mass: 172.052429494 Da
XLogP3: 2.2
Topological polar surface area: 34.1 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 2
Covalent units: 1
Defined stereocentres: 0

Also known as

Vitamin K32-Methyl-1,4-naphthoquinoneKayquinoneMenaphthoneThyloquinoneKanoneKappaxinKayklot

16 more reported names

KlottonePanosine2-Methyl-1,4-naphthalenedioneKolklot2-MethylnaphthoquinoneKareonKoaxinKipcaAquinoneKaergonaMenadionMenaphthonProkayvitAquakaySynkayKativ-G

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External database identifiers

ChEBI:CHEBI:28869
ChEMBL:CHEMBL590
EPA DTXSID:DTXSID4021715
PubMed:27558805
PubMed:24318724
PubMed:23081798
PubMed:23039745
PubMed:22999172
PubMed:22956199
PubMed:22910835
PubMed:22891633
PubMed:22878737
PubMed:22863063
PubMed:22821789
PubMed:22805759

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

Each link searches that source for this identity. A link is a research route, not a claim that the source holds an exact record. What each source is, and its legal weight

Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal US EPA CompTox CTX APIs

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

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