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Official EU label nameGlossary entry 11379

GLYCYRRHIZIC ACID

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

0 markets with evidence
Markets checked
13
Markets with evidence
0
Evidence gaps
13
Resolved identifiers
2

Resolved substance identity

CAS:1405-86-3
EC:215-785-7
Ingredient index records:
GLYCYRRHIZIC ACID
Cosmetic functions: HUMECTANT, SKIN CONDITIONING

Glycyrrhizic acid

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1 matched or reported name
GLYCYRRHIZIC ACID

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name GLYCYRRHIZIC ACID.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 1405-86-3
CAS 1405-86-3PubChem CID 14982

Glycyrrhizin

Glycyrrhizinic acid is a triterpenoid saponin that is the glucosiduronide derivative of 3beta-hydroxy-11-oxoolean-12-en-30-oic acid. It has a role as an EC 3.4.21.5 (thrombin) inhibitor and a plant metabolite. It is a glucosiduronic acid, a pentacyclic triterpenoid, a tricarboxylic acid, an enone and a triterpenoid saponin. It is a conjugate acid of a glycyrrhizinate(3-). — ChEBI

IUPAC name
(2S,3S,4S,5R,6R)-6-[(2S,3R,4S,5S,6S)-2-[[(3S,4aR,6aR,6bS,8aS,11S,12aR,14aR,14bS)-11-carboxy-4,4,6a,6b,8a,11,14b-heptamethyl-14-oxo-2,3,4a,5,6,7,8,9,10,12,12a,14a-dodecahydro-1H-picen-3-yl]oxy]-6-carboxy-4,5-dihydroxyoxan-3-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid
Molecular formula
C42H62O16
Molecular weight
822.9 g/mol
Exact mass
822.40378589 Da
XLogP3
3.7
Topological polar surface area
267.0 Ų
Hydrogen-bond donors
8
Hydrogen-bond acceptors
16
Covalent units
1
Defined stereocentres
19

Also known as

Glycyrrhizic acidGlycyronGlycyrrhizinic acidpotenlinibeta-GlycyrrhizinGlycyrrhetinic acid glycosideGlizigen18beta-Glycyrrhizic acid
16 more reported names
glycyrrhizate18-beta-Glycyrrhizic acidGlycyrrizinRizinsan K2 A2 (free acid)HSDB 496NSC-167409NSC-234419CHEBI:15939EINECS 215-785-7NSC 167409NSC 234419UNII-6FO62043WKBRN 0077922CCRIS 84446FO62043WK20beta-Carboxy-11-oxo-30-norolean-12-en-3beta-yl-2-O-beta-D-glucopyranuronosyl-alpha-D-glucopyranosiduronic acid
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External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

Each link searches that source for this identity. A link is a research route, not a claim that the source holds an exact record. What each source is, and its legal weight

Cosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortalUS EPA CompTox CTX APIs

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

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