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Official EU label nameGlossary entry 10035

ETHYL CAFFEATE

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

0 markets with evidence
Markets checked
13
Markets with evidence
0
Evidence gaps
13
Resolved identifiers
1

Resolved substance identity

CAS:102-37-4
Ingredient index records:
ETHYL CAFFEATE
Cosmetic functions: SKIN CONDITIONING

2-Propenoic Acid, 3-(3,4-Dihydroxyphenyl)-, Ethyl Ester

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1 matched or reported name
ETHYL CAFFEATE

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name ETHYL CAFFEATE.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

Check the markets and their sourcesSearch every market for this name

Chemical identity and properties

PubChem 2D chemical structure for CAS 102-37-4
CAS 102-37-4PubChem CID 5317238

Ethyl Caffeate

Ethyl trans-caffeate is an ethyl ester resulting from the formal condensation of the carboxy group of trans-caffeic acid with ethanol. It has a role as an antineoplastic agent and an anti-inflammatory agent. It is an ethyl ester and an alkyl caffeate ester. It is functionally related to a trans-caffeic acid. — ChEBI

IUPAC name
ethyl (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate
Molecular formula
C11H12O4
Molecular weight
208.21 g/mol
Exact mass
208.07355886 Da
XLogP3
2.6
Topological polar surface area
66.8 Ų
Hydrogen-bond donors
2
Hydrogen-bond acceptors
4
Covalent units
1
Defined stereocentres
0

Also known as

ethyl trans-caffeateEthyl 3,4-dihydroxycinnamateCaffeic acid ethyl ester76GBB1JU5YCHEBI:132714RefChem:596426108-430-1Ethyl 3-(3,4-dihydroxyphenyl)acrylate
16 more reported names
(E)-Ethyl Dihydroxycinnamate(E)-ethyl caffeate4gqqEthyl (2e)-3-(3,4-Dihydroxyphenyl)prop-2-Enoate(E)-ethyl 3-(3,4-dihydroxyphenyl)acrylateHY-N6966NSC-619661AC-34380ethyl 3-(3,4-dihydroxyphenyl)prop-2-enoate2-Propenoic acid, 3-(3,4-dihydroxyphenyl)-, ethyl ester3-(3,4-Dihydroxy-phEthyl (E)-3-(3,4-dihydroxyphenyl)acrylateUNII-76GBB1JU5Y3,4-Dihydroxycinnamic acid ethyl ester3-(3,4-Dihydroxy-phenyl)-acrylic acid ethyl esterEthyl caffeate [M+H]+
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External database identifiers

Evidence from additional scientific databases

EMBL-EBI ChEBI
Exact identifier matchCHEBI:132714

ethyl trans-caffeate

An ethyl ester resulting from the formal condensation of the carboxy group of trans-caffeic acid with ethanol.

Formula
C11H12O4
Average mass
208.213 g/mol
Monoisotopic mass
208.07356 Da
Formal charge
0
  • alkyl caffeate ester — is a (CHEBI:65331)
  • ethyl ester — is a (CHEBI:23990)
  • anti-inflammatory agent — has role (CHEBI:67079)
  • antineoplastic agent — has role (CHEBI:35610)
  • trans-caffeic acid — has functional parent (CHEBI:16433)
  • anti-inflammatory agent — has role (CHEBI:67079)
  • antineoplastic agent — has role (CHEBI:35610)
  • alkyl caffeate ester — is a (CHEBI:65331)
  • ethyl ester — is a (CHEBI:23990)
Additional curated names
ethyl (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoateethyl (2E)-3-(3,4-dihydroxyphenyl)acrylateethyl 3,4-dihydroxycinnamateethyl caffeate(E)-ethyl 3-(3,4-dihydroxyphenyl)acrylate(E)-ethyl 3,4-dihydroxycinnamate(E)-ethyl caffeate
Cross-references from this source
  • CAS: 102-37-4 — ChemIDplus
  • REGISTRY_NUMBER: 2106401 — Reaxys
  • MANUAL_X_REF: 5317238 — PubChem Compound
  • MANUAL_X_REF: Ethyl_caffeate — Wikipedia

Mapped by: Exact CAS cross-reference in the ChEBI compound record. Source updated: 2016-08-04. Retrieved: 2026-08-31. Open source record

NIH PubChem PUG-View
Exact identifier match5317238

Attributed physical-property, hazard, environmental and use annotations.

  • Signal: Warning Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H302 (20%): Harmful if swallowed [Warning Acute toxicity, oral]; H315 (80%): Causes skin irritation [Warning Skin corrosion/irritation]; H319 (80%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H335 (80%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 5 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P264, P270, P301+P317, P330, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory. Source: European Chemicals Agency (ECHA)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
EMBL-EBI ChEBIExact match2026-08-31
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

Each link searches that source for this identity. A link is a research route, not a claim that the source holds an exact record. What each source is, and its legal weight

Cosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortalUS EPA CompTox CTX APIs

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

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