Official EU label nameGlossary entry 10002
ETHOXYDIGLYCOL
This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.
Global evidence snapshot
The resolved identity has matching regulatory evidence in 6 of 13 indexed market datasets: 5 country records and 1 EU Annex records. Every result and evidence gap is listed below.
Markets checked
13
Markets with evidence
6
Evidence gaps
7
Resolved identifiers
2
Resolved substance identity
CAS:111-90-0
EC:203-919-7
Ingredient index records:
ETHOXYDIGLYCOL
Cosmetic functions: HUMECTANT, PERFUMING, SOLVENT
2-(2-Ethoxyethoxy)ethanol; Carbitol; Diethylene glycol monoethyl ether; DEGEE
Inventory restriction note: III/297
6 matched or reported names
ETHOXYDIGLYCOL2-(2-ethoxyethoxy)ethanol Diethylene Glycol Monoethyl Ether (DEGEE), EthoxydiglycolEthoxydiglycol2-(2-Ethoxyethoxy)ethanol diethylene glycol monoethyl ether (DEGEE; ethoxydiglycol)2-(ethoxyethoxy)-ethanol Diethylene glycol monoethyl ether (DEGEE) Ethoxydiglycol CAS No 111-90-02-(2-Ethoxyethoxy) ethanol diethylene glycol monoethyl ether (DEGEE) Ethoxydiglycol (CAS No.: 111-90-0) (
Regulatory evidence in all 13 markets
Open each matched record for its scope, concentration, conditions, warnings and official source version.
Swipe or scroll horizontally to see dataset coverage and next actions.
| Market | Result | Records | Dataset | Meaning / next action |
|---|---|---|---|---|
| European Union EU | Restricted | 1Open record 1 | Complete annex dataset Regulation (EC) 1223/2009 consolidated to 1 May 2026 | Review every linked record and exact conditions. |
| Great Britain GB | Restricted | 1Open record 1 | Complete consolidated annex dataset GB retained Regulation 1223/2009 schedules, effective 15 August 2026 | Review every linked record and exact conditions. |
| Canada CA | No local match | 0 | Complete Hotlist snapshot Health Canada Cosmetic Ingredient Hotlist, 13 August 2025 | The Hotlist is an administrative compliance tool, not an exhaustive safety approval list. |
| New Zealand NZ | Restricted | 1Open record 1 | Complete schedules dataset Cosmetic Products Group Standard schedules effective 1 January 2026 | Review every linked record and exact conditions. |
| ASEAN ASEAN | Restricted | 1Open record 1 | Complete regional annex dataset ASEAN Cosmetic Directive annexes 2026-1, 22 June 2026 | Review every linked record and exact conditions. |
| China CN | No local match | 0 | Complete prohibited catalogues plus official-source workflow NMPA 2021 banned catalogues plus dynamic IECIC List I/List II system current since 2025 | IECIC listing is not blanket approval; absence may require the new cosmetic ingredient route, and restrictions are checked separately. |
| Japan JP | No local match | 0 | Complete Standards appendices dataset MHLW Standards for Cosmetics official English source and Japanese amendments checked for the imported snapshot | The Japanese text and subsequent notices are canonical; no local match is not a product-compliance conclusion. |
| South Korea KR | No local match | 0 | Complete current appendix dataset MFDS Notice 2026-19, effective 18 March 2026 | Korean source wording is canonical and other positive lists/notices may still apply to the formulation. |
| United States US | No local match | 0 | Complete enumerated federal ingredient rules eCFR Title 21 issue date 27 August 2026 | FDA has no general approved-cosmetic-ingredient catalogue; absence from these sections is not approval or proof of safety. |
| Australia AU | No local match | 0 | Complete cosmetic-relevant Poisons Standard subset plus official workflow Therapeutic Goods (Poisons Standard—June 2026) Instrument 2026 | An AICIS Inventory match is not cosmetic approval; no Inventory match can indicate a new, exempted, reported or confidential introduction. |
| Brazil BR | No local match | 0 | Complete prohibited dataset plus current restricted-list workflow ANVISA RDC 1.029/2026 and RDC 1.030/2026, published 15 June 2026 | RDC 1.030/2026 amends rather than replaces the prohibited baseline, and the second restricted-list revision was still under consultation in July 2026. |
| India IN | Restricted | 1Open record 1 | Complete current Part 2 dataset plus official workflow for Parts 1, 3 and 4 Cosmetics Rules 2020 plus current BIS IS 4707 parts (1:2020, 2:2025, 3:2025, 4:2022) | Review every linked record and exact conditions. |
| Saudi Arabia SA | Restricted | 1Open record 1 | Complete official list index SFDA live prohibited/restricted lists, snapshot 30 August 2026 | Review every linked record and exact conditions. |
No market rows match this filter.
Matching market records and conditions
Great Britain
GB retained Regulation 1223/2009 schedules, effective 15 August 2026New Zealand
Cosmetic Products Group Standard schedules effective 1 January 2026ASEAN
ASEAN Cosmetic Directive annexes 2026-1, 22 June 2026India
Cosmetics Rules 2020 plus current BIS IS 4707 parts (1:2020, 2:2025, 3:2025, 4:2022)Saudi Arabia
SFDA live prohibited/restricted lists, snapshot 30 August 2026Exact Annex II–VI evidence
Annex IIIentry 297
Open full regulatory recordETHOXYDIGLYCOL
Product scope: (a) Oxidative hair day products (b) Non-oxidative hair dye products (c) Rinse-off products other than hair dye products (d) Other non-spray cosmetic products (e) The following spray products: fine fragrances, hair sprays, antiperspirant and deodorant
Maximum concentration: (a) 7% (b) 5% (c) 10% (d) 2,6% (e)2,6%
Restrictions: (a) to (e): The level of ethylene glycol impurity in Ethoxydiglycol must be ≤ 0,1 %. Not to be used in eye products and oral products
Chemical identity and properties
CAS 111-90-0PubChem CID 8146
Diethylene Glycol Monoethyl Ether
Diethylene glycol monoethyl ether is a primary alcohol that is ethanol substituted by a 2-ethoxyethoxy group at position 2. It has a role as a protic solvent. It is a primary alcohol, a glycol ether, a diether and a hydroxypolyether. It is functionally related to a diethylene glycol. — ChEBI
- IUPAC name
- 2-(2-ethoxyethoxy)ethanol
- Molecular formula
- C6H14O3
- Molecular weight
- 134.17 g/mol
- Exact mass
- 134.094294304 Da
- XLogP3
- -0.5
- Topological polar surface area
- 38.7 Ų
- Hydrogen-bond donors
- 1
- Hydrogen-bond acceptors
- 3
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
CARBITOLTranscutolEthoxydiglycolEthyl carbitolDioxitolEthoxy diglycolCarbitol solventSolvolsol
16 more reported names
Ethyl digolDiethylene glycol ethyl etherCarbitol cellosolveEthanol, 2-(2-ethoxyethoxy)-Losungsmittel apvDowanol DEEthyl diethylene glycolDiglycol monoethyl ether3,6-Dioxa-1-octanolDEGMEEEktasolve DEDowanol 17KarbitolEthylene diglycol monoethyl ether2-(2-Ethoxyethoxy) ethanolDiethyleneglycol monoethyl ether
External database identifiers
- ChEBI:CHEBI:40572
- ChEMBL:CHEMBL1230841
- EPA DTXSID:DTXSID2021941
- PubMed:33358762
- PubMed:25959454
- PubMed:22218002
- PubMed:22026377
- PubMed:21330095
- PubMed:20521179
- PubMed:19589377
- PubMed:19333469
- PubMed:19152165
- PubMed:18563577
- PubMed:18205921
- PubMed:18068919
Evidence from additional scientific databases
NIH PubChem PUG-View
Exact identifier match8146
Attributed physical-property, hazard, environmental and use annotations.
- Autoignition Temperature: 400 °F (USCG, 1999) Source: CAMEO Chemicals
- Autoignition Temperature: 400 °F (204 °C) Source: Hazardous Substances Data Bank (HSDB)
- Autoignition Temperature: 204 °C Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Boiling Point: 396 °F at 760 mmHg (NTP, 1992) Source: CAMEO Chemicals
- Boiling Point: boiling point equals 396 °F Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Boiling Point: 196 °C Source: Hazardous Substances Data Bank (HSDB)
- Boiling Point: 196-202 °C Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Boiling Point: 396 °F Source: Occupational Safety and Health Administration (OSHA)
- Boiling Point: 196 °C @760 [mm Hg] Source: PAC Chemical Database, U.S. Department of Energy
- Color/Form: Colorless liquid Source: Hazardous Substances Data Bank (HSDB)
- Density: 0.99 at 68 °F (USCG, 1999) - Less dense than water; will float Source: CAMEO Chemicals
- Density: 0.9885 g/cu cm at 20 °C Source: Hazardous Substances Data Bank (HSDB)
- Density: Relative density (water = 1): 0.99 Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Density: 0.99 Source: Occupational Safety and Health Administration (OSHA)
- Density: 0.986 @ 20°C Source: PAC Chemical Database, U.S. Department of Energy
- Flash Point: 205 °F (NTP, 1992) Source: CAMEO Chemicals
- Flash Point: Flash point equals 205 °F Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Flash Point: 196 °F (91 °C) (CLOSED CUP) Source: Hazardous Substances Data Bank (HSDB)
- Flash Point: 96 °C o.c. Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Flash Point: 205 °F Source: Occupational Safety and Health Administration (OSHA)
- LogP: log Kow = -0.54 Source: Hazardous Substances Data Bank (HSDB)
- LogP: -0.15 (estimated) Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Melting Point: -108 °F (NTP, 1992) Source: CAMEO Chemicals
- Melting Point: Freezing point = -54.0 °C Source: Hazardous Substances Data Bank (HSDB)
- Melting Point: -76 °C Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Melting Point: -108 °F Source: Occupational Safety and Health Administration (OSHA)
- Odor: Mild, pleasant odor Source: Hazardous Substances Data Bank (HSDB)
- Physical Description: Diethylene glycol monoethyl ether appears as a colorless, slightly viscous liquid with a mild pleasant odor. Flash point near 190 °F. Used to make soaps, dyes, and other chemicals. Source: CAMEO Chemicals
- Physical Description: Liquid; CBI; Other Solid Source: EPA Chemical Data Reporting (CDR)
- Physical Description: A clear slightly viscous liquid with a mild pleasant odor; [CAMEO] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Physical Description: COLOURLESS HYGROSCOPIC LIQUID. Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Physical Description: A colorless, slightly viscous liquid with a mildly sweet odor. Source: Occupational Safety and Health Administration (OSHA)
- Refractive Index: Index of refraction: 1.4273 at 20 °C/D Source: Hazardous Substances Data Bank (HSDB)
- Solubility: greater than or equal to 100 mg/mL at 68 °F (NTP, 1992) Source: CAMEO Chemicals
- Solubility: Miscible with ether, pyridine, chloroform Source: Hazardous Substances Data Bank (HSDB)
- Solubility: Miscible with the common organic solvents. Source: Hazardous Substances Data Bank (HSDB)
- Solubility: Miscible with ethanol, acetone, benzene; very soluble in ethyl ether Source: Hazardous Substances Data Bank (HSDB)
- Solubility: In water, miscible at 25 °C Source: Hazardous Substances Data Bank (HSDB)
- Solubility: Solubility in water: very good Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Vapor Pressure: 0.13 mmHg at 77 °F (NTP, 1992) Source: CAMEO Chemicals
- Vapor Pressure: 0.12 [mmHg] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Vapor Pressure: Vapor pressure, Pa at 25 °C: 19 Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Vapor Pressure: 0.13 mmHg Source: Occupational Safety and Health Administration (OSHA)
- Vapor Pressure: 0.126 [mm Hg] @25 °C Source: PAC Chemical Database, U.S. Department of Energy
- Viscosity: 3.85 mPa.s (=cPs) at 25 °C Source: Hazardous Substances Data Bank (HSDB)
- First Aid: EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.; SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.; INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) shou Source: CAMEO Chemicals
- Note: This chemical does not meet GHS hazard criteria for 90.4% (4397 of 4862) of all reports. Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: Not Classified; Reported as not meeting GHS hazard criteria by 4397 of 4862 companies (only 9.6% companies provided GHS information). For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: Aggregated GHS information provided per 4862 reports by companies from 13 notifications to the ECHA C&L Inventory.; Reported as not meeting GHS hazard criteria per 4397 of 4862 reports by companies.; There are 11 notifications provided by 465 of 4862 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- Signal: Danger Source: NITE-CMC
- GHS Hazard Statements: H227: Combustible liquid [Warning Flammable liquids]; H320: Causes eye irritation [Warning Serious eye damage/eye irritation]; H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure] Source: NITE-CMC
- Precautionary Statement Codes: P210, P260, P264, P264+P265, P270, P280, P305+P351+P338, P319, P337+P317, P370+P378, P403, and P501 (click each P-code to see the statement) Source: NITE-CMC
- NFPA Health Rating: 2 - Materials that, under emergency conditions, can cause temporary incapacitation or residual injury. Source: Hazardous Substances Data Bank (HSDB)
- NFPA Fire Rating: 2 - Materials that must be moderately heated or exposed to relatively high ambient temperatures before ignition can occur. Materials would not under normal conditions form hazardous atmospheres with air, but under high ambient temperatures or under moderate heating could release vapor in sufficient quantities to produce hazardous atmospheres with air. Source: Hazardous Substances Data Bank (HSDB)
- NFPA Instability Rating: 0 - Materials that in themselves are normally stable, even under fire conditions. Source: Hazardous Substances Data Bank (HSDB)
- Cosmetic Ingredient Review Finding(s): Safe in the present practices of use and concentration. Ingredient, concentration, and use information are available in documents discoverable at https://cir-reports.cir-safety.org Source: Cosmetic Ingredient Review (CIR)
- Environmental Bioconcentration: An estimated BCF of 3 was calculated in fish for diethylene glycol monoethyl ether(SRC), using a log Kow of -0.54(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC). Source: Hazardous Substances Data Bank (HSDB)
- Environmental Fate: TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 12(SRC), determined from a log Kow of -0.54(2) and a regression-derived equation(3), indicates that diethylene glycol monoethyl ether is expected to have very high mobility in soil(SRC). Volatilization of diethylene glycol monoethyl ether from moist soil surfaces is not expected to be an important fate process(SRC) given an estimated Henry's Law constant of 2.2X10-8 atm-cu m/mole(SRC), derived from its vapor pressure, 0.126 mm Hg(4), and assigned value for water solubility of 1X10+6 mg/L (miscible)(5). Diethylene glycol monoethyl ether is expected to volatilize from dry soil surfaces(SRC) based upon its vapor pressure(4). Aerobic screening test data(6-11) indicate that rapid aerobic biodegradation is likely to be the most important mechanism for the removal of diethylene glycol monoethyl ether from soil. Biodegradation of 48%(6) to 87%(7) were reported in non-acclimated cultures incubated for 20 days. Source: Hazardous Substances Data Bank (HSDB)
- Environmental Fate: AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 12(SRC), determined from a log Kow of -0.54(2) and a regression-derived equation(3), indicates that diethylene glycol monoethyl ether is not expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is not expected(3) based upon an estimated Henry's Law constant of 2.2X10-8 atm-cu m/mole(SRC), derived from its vapor pressure, 0.126 mm Hg(4), and assigned value for water solubility of 1X10+6 mg/L (5)(miscible). According to a classification scheme(6), an estimated BCF of 3(SRC), from its log Kow(2) and a regression-derived equation(7), suggests the potential for bioconcentration in aquatic organisms is low(SRC). Diethylene glycol monoethyl ether is not expected to undergo hydrolysis or direct photolysis in aquatic environments(SRC). Alcohols and ethers are generally resistant to hydrolysis(3). They do not absorb UV light in the environmental range of >290 nm and are commonly used as solvents for obtaining UV spectra(14). Aerobic screening test data(8-13) indicate that rapid aerobic biodegradation is likely to be the most important mechanism for the removal of diethylene gl Source: Hazardous Substances Data Bank (HSDB)
- Environmental Fate: ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), diethylene glycol monoethyl ether, which has a vapor pressure of 0.126 mm Hg at 25 °C(2), is expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase diethylene glycol monoethyl ether is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 6.7 hours(SRC), calculated from its rate constant of 5.72X10-11 cu cm/molecule-sec at 23 °C(3). Diethylene glycol monoethyl ether does not contain chromophores that absorb at wavelengths >290 nm and therefore is not expected to be susceptible to direct photolysis by sunlight(4). Source: Hazardous Substances Data Bank (HSDB)
- Consumer Uses: Solvent; Cleaning agent; Fragrance; Not Known or Reasonably Ascertainable Source: EPA Chemical Data Reporting (CDR)
- Industry Uses: Cleaning agent; Not Known or Reasonably Ascertainable; Coalescing agent; Laboratory chemicals; Solvent; Other; Solubility enhancer Source: EPA Chemical Data Reporting (CDR)
- Cosmetic Ingredient Review Link: CIR ingredient: Ethoxydiglycol Source: Cosmetic Ingredient Review (CIR)
- Sources/Uses: Used in lubricating oil and braking fluid; [ChemIDplus] Used as a solvent for cellulose esters, lacquers, varnishes, enamels, dyestuffs, wood stains, gums, and resins; [Merck Index, 1800] Used in textile printing; [CHEMINFO] Used in photography (solvent for color processing); [www.ci.tucson.az.us/arthazards/medium.html] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Industrial Processes with risk of exposure: Painting (Solvents) [Category: Paint]; Photographic Processing [Category: Other]; Textiles (Printing, Dyeing, or Finishing) [Category: Industry] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Uses: AS SOLVENT FOR CELLULOSE ESTERS, IN LACQUER & THINNER FORMULATIONS; IN QUICK DRYING VARNISHES AND ENAMELS, FOR DYESTUFFS AND WOOD STAINS. Source: Hazardous Substances Data Bank (HSDB)
- Uses: A DILUENT FOR HYDRAULIC BRAKE FLUIDS; SOLVENT IN PROTECTIVE COATINGS, TEXTILE DYEING & PRINTING; SOLVENT IN COSMETICS, TOILETRIES Source: Hazardous Substances Data Bank (HSDB)
- Uses: Used as a chemical intermediate for the synthesis of 2-(2-ethoxyethoxy)ethyl acrylate. Source: Hazardous Substances Data Bank (HSDB)
- Uses: Solvent for dyes, nitrocellulose, and resins; mutual solvent for mineral-oil-soap and mineral-oil-sulfonated-oil mixtures; nonaqueous stains for wood, for setting the twist and conditioning yarns and cloth; textile printing, textile soaps, lacquers, organic synthesis; brake fluid diluent. Source: Hazardous Substances Data Bank (HSDB)
- Uses: Inert ingredient in pesticide products. Diethylene glycol monoethyl ether is found on List 2: potentially toxic other ingredients/high priority for testing inerts. ... List 2 inert ingredients are structurally similar to chemicals known to be toxic; some have data suggesting a concern. Source: Hazardous Substances Data Bank (HSDB)
Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record
Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.
Additional source coverage and match status
| Source | Result | Checked |
|---|---|---|
| NIH PubChem PUG-View | Exact match | 2026-08-31 |
A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.
Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
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Official source and scope
Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.
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