CAS 112-15-2PubChem CID 8165
2-(2-Ethoxyethoxy)ethyl acetate
- IUPAC name
- 2-(2-ethoxyethoxy)ethyl acetate
- Molecular formula
- C8H16O4
- Molecular weight
- 176.21 g/mol
- Exact mass
- 176.10485899 Da
- XLogP3
- 0.2
- Topological polar surface area
- 44.8 Ų
- Hydrogen-bond donors
- 0
- Hydrogen-bond acceptors
- 4
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
Carbitol acetateDiethylene glycol monoethyl ether acetateEktasolve de acetateEthoxydiglycol acetateKarbitolacetatGlycol ether de acetate2-(2-Ethoxyethoxy)ethanol acetateEthanol, 2-(2-ethoxyethoxy)-, acetate
16 more reported names
Diethylene glycol ethyl ether acetateDiglycol monoethyl ether acetateKarbitolacetat [Czech]Acetic acid 2-(2-ethoxyethoxy)ethyl esterNSC 8702HSDB 5555W5EIM81UBXEINECS 203-940-12-(2-Ethoxyethoxy)ethylester kyseliny octoveBRN 1764643AI3-01953Ethanol, 2-(2-ethoxyethoxy)-, 1-acetateNSC-87022-(2-Ethoxyethoxy)ethylester kyseliny octove [Czech]3,6-DIOXAOCTYL ACETATEEC 203-940-1
External database identifiers
- ChEMBL:CHEMBL3185106
- EPA DTXSID:DTXSID6026905
Evidence from additional scientific databases
NIH PubChem PUG-View
Exact identifier match8165
Attributed physical-property, hazard, environmental and use annotations.
- Autoignition Temperature: 563 °F (295 °C) Source: Hazardous Substances Data Bank (HSDB)
- Boiling Point: 423.32 °F at 760 mmHg (USCG, 1999) Source: CAMEO Chemicals
- Boiling Point: 218.5 °C Source: Hazardous Substances Data Bank (HSDB)
- Boiling Point: 423.32 °F Source: Occupational Safety and Health Administration (OSHA)
- Boiling Point: 218.5 °C @760 [mm Hg] Source: PAC Chemical Database, U.S. Department of Energy
- Color/Form: Colorless liquid Source: Hazardous Substances Data Bank (HSDB)
- Density: 1.0114 at 68 °F (USCG, 1999) - Denser than water; will sink Source: CAMEO Chemicals
- Density: 1.0096 g/cu cm at 20 °C Source: Hazardous Substances Data Bank (HSDB)
- Density: 1.0114 Source: Occupational Safety and Health Administration (OSHA)
- Density: 1.0096 @ 20°C Source: PAC Chemical Database, U.S. Department of Energy
- Flash Point: 230 °F (USCG, 1999) Source: CAMEO Chemicals
- Flash Point: 241 °F (116 °C) OC Source: Hazardous Substances Data Bank (HSDB)
- Flash Point: 230 °F Source: Occupational Safety and Health Administration (OSHA)
- Melting Point: -13 °F (USCG, 1999) Source: CAMEO Chemicals
- Melting Point: -25 °C Source: Hazardous Substances Data Bank (HSDB)
- Melting Point: -13 °F Source: Occupational Safety and Health Administration (OSHA)
- Melting Point: -25 °C Source: PAC Chemical Database, U.S. Department of Energy
- Odor: Characteristic: quality: sweet; hedonic tone: pleasant to unpleasant. Source: Hazardous Substances Data Bank (HSDB)
- Physical Description: Diethylene glycol ethyl ether acetate is a colorless liquid. (USCG, 1999) Source: CAMEO Chemicals
- Physical Description: Liquid Source: EPA Chemical Data Reporting (CDR)
- Physical Description: Colorless liquid; [Hawley] Hygroscopic; [HSDB] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Physical Description: A colorless liquid. Source: Occupational Safety and Health Administration (OSHA)
- Refractive Index: Index of refraction: 1.4213 at 20 °C/D Source: Hazardous Substances Data Bank (HSDB)
- Solubility: Miscible with water, alcohol, ether, most oils Source: Hazardous Substances Data Bank (HSDB)
- Solubility: Very soluble in acetone, ethyl ether, ethanol Source: Hazardous Substances Data Bank (HSDB)
- Solubility: In water, 1.0X10+6 mg/L at 20 °C /miscible/ Source: Hazardous Substances Data Bank (HSDB)
- Vapor Pressure: 0.09 [mmHg] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Vapor Pressure: 9.89X10-2 mm Hg at 20 °C Source: Hazardous Substances Data Bank (HSDB)
- Viscosity: 0.0279 cP at 20 °C Source: Hazardous Substances Data Bank (HSDB)
- First Aid: Get medical attention.; INHALATION: Remove to fresh air. If breathing has stopped, give artificial respiration. If breathing is difficult, give oxygen.; EYES: Flush with water for at least 15 min., lifting lids occasionally.; SKIN: Remove contaminated clothing and shoes. Wash with soap and water. (USCG, 1999) Source: CAMEO Chemicals
- Note: This chemical does not meet GHS hazard criteria for 2.9% (27 of 924) of reports. Source: European Chemicals Agency (ECHA)
- Signal: Warning Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: H315 (12.1%): Causes skin irritation [Warning Skin corrosion/irritation]; H319 (97%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] Source: European Chemicals Agency (ECHA)
- Precautionary Statement Codes: P264, P264+P265, P280, P302+P352, P305+P351+P338, P321, P332+P317, P337+P317, and P362+P364 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: Aggregated GHS information provided per 924 reports by companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Reported as not meeting GHS hazard criteria per 27 of 924 reports by companies.; There are 9 notifications provided by 897 of 924 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- NFPA Health Rating: 1 - Materials that, under emergency conditions, can cause significant irritation. Source: Hazardous Substances Data Bank (HSDB)
- NFPA Fire Rating: 1 - Materials that must be preheated before ignition can occur. Materials require considerable preheating, under all ambient temperature conditions, before ignition and combustion can occur. Source: Hazardous Substances Data Bank (HSDB)
- NFPA Instability Rating: 0 - Materials that in themselves are normally stable, even under fire conditions. Source: Hazardous Substances Data Bank (HSDB)
- Environmental Bioconcentration: An estimated BCF of 3 was calculated in fish for diethylene glycol monoethyl ether acetate(SRC), using an estimated log Kow of 0.32(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC). Source: Hazardous Substances Data Bank (HSDB)
- Environmental Fate: TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 10(SRC), determined from an assigned value for water solubility of 1X10+6 mg/L (miscible)(2) and a regression-derived equation(3), indicates that diethylene glycol monoethyl ether acetate is expected to have very high mobility in soil(SRC). Volatilization of 2-(2-ethyoxyethoxy)ethyl acetate from moist soil surfaces is not expected to be an important fate process(SRC) given an estimated Henry's Law constant of 2.3X10-8 atm-cu m/mole(SRC), derived from its vapor pressure, 9.89X10-2 mm Hg(4), and assigned value for water solubility(2). Diethylene glycol monoethyl ether acetate is not expected to volatilize from dry soil surfaces(SRC) based upon its vapor pressure(4). Utilizing the Japanese MITI test, 98-103% of the theoretical BOD was reached over a 4 week incubation period using an activated sludge and an initial chemical concentration of 100 mg/L(5), indicating that biodegradation in soil is an important environmental fate process(SRC). Source: Hazardous Substances Data Bank (HSDB)
- Environmental Fate: AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 10(SRC), determined from an assigned value for water solubility of 1X10+6 mg/L (miscible)(2) and a regression-derived equation(3), indicates that diethylene glycol monoethyl ether acetate is not expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is not expected(3) based upon an estimated Henry's Law constant of 2.3X10-8 atm-cu m/mole(SRC), derived from its vapor pressure, 9.89X10-2 mm Hg(4), and assigned value for water solubility(2). According to a classification scheme(5), an estimated BCF of 3(SRC), from an estimated log Kow(6) and a regression-derived equation(7), suggests the potential for bioconcentration in aquatic organisms is low(SRC). Estimated hydrolysis half-lives of 300 and 30 days at pHs 7 and 8, respectively(8), suggest that hydrolysis is only expected to be an important process under alkaline conditions(SRC). Utilizing the Japanese MITI test, 98-103% of the theoretical BOD was reached over a 4 week incubation period using an activated sludge and an initial chemical concentration of 100 mg/L(9), indicating that biodegradation in soil is an important Source: Hazardous Substances Data Bank (HSDB)
- Environmental Fate: ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), diethylene glycol monoethyl ether acetate, which has a vapor pressure of 9.89X10-2 mm Hg at 20 °C(2), is expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase diethylene glycol monoethyl ether acetate is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 13 hours(SRC), calculated from its rate constant of 2.9X10-11 cu cm/molecule-sec at 25 °C(SRC) that was derived using a structure estimation method(3). Diethylene glycol monoethyl ether acetatecontains chromophores that absorb at wavelengths >290 nm(4) and therefore may be susceptible to direct photolysis by sunlight(SRC). Source: Hazardous Substances Data Bank (HSDB)
- Consumer Uses: Not Known or Reasonably Ascertainable Source: EPA Chemical Data Reporting (CDR)
- Industry Uses: Not Known or Reasonably Ascertainable Source: EPA Chemical Data Reporting (CDR)
- Sources/Uses: Used as solvent for cellulose esters, gums, resins, coatings, lacquers, and printing inks; [Hawley] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Industrial Processes with risk of exposure: Painting (Solvents) [Category: Paint]; Working with Glues and Adhesives [Category: Other] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Uses: Solvent for cellulose esters, gums, resins; coatings and lacquers; printing inks. Source: Hazardous Substances Data Bank (HSDB)
- Uses: Solvent, eg, for latex paints, lacquers and printing inks Source: Hazardous Substances Data Bank (HSDB)
Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record
Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.
Additional source coverage and match status
| Source | Result | Checked |
|---|---|---|
| NIH PubChem PUG-View | Exact match | 2026-08-31 |
A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.