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Annex III Entry 310 28/07/2020

CLIMBAZOLE

1-(4-Chlorophenoxy)-1-(imidazol-1-yl)-3,3-dimethylbutan-2-one

CLIMBAZOLE is listed in Annex III and may only be used under the conditions shown in this record. Maximum concentration in this record: 2,0 %.

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Restricted substance— Annex III, EU Regulation 1223/2009
Max conc.: 2,0 %
Entry: 310

Record details

Maximum concentration

2,0 %

Product type

Rinse-off anti-dandruff shampoo

Other restrictions

For purposes other than inhibiting the development of micro-organisms in the product. This purpose has to be apparent from the presentation of the product.

INCI glossary name

CLIMBAZOLE

Chemical name

1-(4-Chlorophenoxy)-1-(imidazol-1-yl)-3,3-dimethylbutan-2-one

Chemical / IUPAC name

1-(4-Chlorophenoxy)-1-(imidazol-1-yl)-3,3-dimethylbutan-2-one

Regulatory information

Regulation

(EU) 2019/698

SCCS opinions

Key data

CAS
38083-17-9;
EC
253-775-4;
Annex
III
Entry number
310

Inventory links for CLIMBAZOLE

Inventory Shared INCI name
Ref 32909

CLIMBAZOLE

CAS: 38083-17-9
EC: 253-775-4

Direct matches are limited for this record, so nearby entries from Annex III are shown as well.

Annex V 32
Shared CAS number

CLIMBAZOLE

CAS: 38083-17-9
EC: 253-775-4
Annex III 312
Nearby record in the same annex

FURFURAL

CAS: 98-01-1
EC: 202-627-7
Annex III 313
Nearby record in the same annex

HEMA

CAS: 868-77-9
EC: 212-782-2
Annex III 307
Nearby record in the same annex

HYDROLYZED WHEAT PROTEIN

CAS: 94350-06-8 / 222400-28-4 / 70084-87-6 / 100209- 50-5
EC: 305-225-0/ -/ 309-358-5
Annex III 305
Nearby record in the same annex

BASIC BLUE 124

CAS: 67846-56-4
EC: 267-370-5
Annex III 304
Nearby record in the same annex

BASIC BROWN 17

CAS: 68391-32-2
EC: 269-944-0

What Annex III means for CLIMBAZOLE

CLIMBAZOLE is a restricted substance under Annex III of EU Cosmetics Regulation 1223/2009. Its use in cosmetics is only permitted under the specific conditions set out in the entry above, including applicable concentration limits, product type restrictions and required warning statements.

When including this substance in a formulation, all conditions — maximum concentration, product scope and warning labels — must be met simultaneously. Compliance with one condition does not override the others.

This record is linked to 1 CosIng inventory ingredient for name and identifier cross-reference. The page also surfaces 12 related annex records with overlapping identifiers, annex logic or naming patterns.

Compliance checklist

  • Ensure formulation concentration does not exceed: 2,0 %
  • Confirm product type compatibility: Rinse-off anti-dandruff shampoo
  • Document conditions of use in the Product Information File (PIF).

Frequently asked questions

CLIMBAZOLE is listed in Annex III of EU Regulation 1223/2009 as a restricted substance. It may only be used under the conditions specified in the entry, including any maximum concentration, product type limitation and required warning statements shown above.

CAS 38083-17-9; is the unique numerical identifier assigned to CLIMBAZOLE by the Chemical Abstracts Service. In cosmetic compliance work, the CAS number is used to cross-reference the substance across regulatory databases, raw material specifications and safety assessment reports. Multiple EU annex entries may share the same CAS number if the same substance appears under different conditions or in different annexes.

The maximum concentration of 2,0 % applies to the concentration of the substance in the ready-to-use cosmetic product. When the substance is supplied as part of a blend or mixture, the calculation must account for the contribution of all sources in the formulation. The combined concentration must not exceed the stated limit.

Use the INCI Checker tool on this site to paste your full ingredient list (INCI) and scan it against all Annex II–VI entries. The tool highlights any ingredients that match restricted, prohibited or allergen-flagged records. This is useful for rapid compliance screening of finished product formulas or raw material declarations.
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Source note for Annex III record CLIMBAZOLE

This page summarizes one Annex III record for CLIMBAZOLE from public European Commission cosmetic materials and adds linked inventory or identifier matches when available.

Use this record page to review Annex III conditions for CLIMBAZOLE, but confirm any final regulatory decision against the current official annex wording and source files.

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