What is CAS 106-92-3 for Allyl glycidyl ether?

CAS 106-92-3 is the unique numerical identifier assigned to Allyl glycidyl ether by the Chemical Abstracts Service. It is used to cross-reference the substance across regulatory databases, raw material specifications and safety assessment reports.

Annex II Entry 997 CMR15/10/2010

Allyl glycidyl ether

Q: How do I check if my product formula contains Allyl glycidyl ether?

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Allyl glycidyl ether is listed in Annex II as a prohibited substance for cosmetic products placed on the EU market.

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Prohibited substance— Annex II, EU Regulation 1223/2009

Entry: 997

CMR

Chemical identity and properties

PubChem 2D chemical structure for CAS 106-92-3

CAS 106-92-3PubChem CID 7838

Allyl glycidyl ether

Allyl glycidyl ether appears as a colorless liquid with a pleasant odor. Slightly less dense than water and insoluble in water. Hence floats on water. Poisonous by ingestion and mildly toxic by inhalation and skin contact. Very irritating to skin and eyes. Used to make other chemicals. — CAMEO Chemicals

IUPAC name: 2-(prop-2-enoxymethyl)oxirane

Molecular formula: C6H10O2
Molecular weight: 114.14 g/mol
Exact mass: 114.068079557 Da
XLogP3: 0.4
Topological polar surface area: 21.8 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 2
Covalent units: 1
Defined stereocentres: 0

Also known as

Glycidyl allyl etherAllyl 2,3-epoxypropyl etherAllylglycidaetherAllil-glicidil-etere1-Allyloxy-2,3-epoxypropane1,2-Epoxy-3-allyloxypropaneDenacol EX 111Propane, 1-(allyloxy)-2,3-epoxy-

16 more reported names

1-(Allyloxy)-2,3-epoxypropane1-Allyloxy-2,3-epoxypropanEther, allyl 2,3-epoxypropylOxyde d'allyle et de glycidyle1-Allilossi-2,3 epossipropano1-Allyloxy-2,3-epoxy-propaanNCI-C56666[(2-Propenyloxy)methyl]oxiraneNSC-631NSC-18596DTXCID6046Oxirane, 2-((2-propen-1-yloxy)methyl)-((ALLYLOXY)METHYL)OXIRANE((2-propenyloxy)methyl)oxiraneOxirane, 2-[(2-propen-1-yloxy)methyl]-RefChem:110869

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEMBL:CHEMBL1528174
EPA DTXSID:DTXSID9039232
PubMed:22412299
PubMed:22056082
PubMed:21971715
PubMed:21888355
PubMed:21800871
PubMed:21332185
PubMed:21319753
PubMed:20599201
PubMed:20520883
PubMed:20482978
PubMed:19994900
PubMed:19994878

Evidence from additional scientific databases

NIH PubChem PUG-View

Exact identifier match7838

Attributed physical-property, hazard, environmental and use annotations.

Autoignition Temperature: 264 °C Source: ILO-WHO International Chemical Safety Cards (ICSCs)

Boiling Point: 309 °F at 760 mmHg (NTP, 1992) Source: CAMEO Chemicals
Boiling Point: 153.9 °C AT 760 MM HG Source: Hazardous Substances Data Bank (HSDB)
Boiling Point: 154 °C Source: ILO-WHO International Chemical Safety Cards (ICSCs)
Boiling Point: 309 °F Source: Occupational Safety and Health Administration (OSHA)
Boiling Point: 309 °F Source: The National Institute for Occupational Safety and Health (NIOSH)

Color/Form: COLORLESS LIQUID Source: Hazardous Substances Data Bank (HSDB)
Color/Form: Colorless liquid ... Source: Hazardous Substances Data Bank (HSDB)

Density: 0.969 at 68 °F (NTP, 1992) - Less dense than water; will float Source: CAMEO Chemicals
Density: SP GR: 0.9698 AT 20 °C/40 °C Source: Hazardous Substances Data Bank (HSDB)
Density: Relative density (water = 1): 0.97 Source: ILO-WHO International Chemical Safety Cards (ICSCs)
Density: 0.97 Source: Occupational Safety and Health Administration (OSHA)
Density: 0.97 Source: The National Institute for Occupational Safety and Health (NIOSH)

Flash Point: 135 °F (NTP, 1992) Source: CAMEO Chemicals
Flash Point: 57 °C Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
Flash Point: 135 °F (OPEN CUP) Source: Hazardous Substances Data Bank (HSDB)
Flash Point: 45 °C c.c. Source: ILO-WHO International Chemical Safety Cards (ICSCs)
Flash Point: 135 °F Source: Occupational Safety and Health Administration (OSHA)
Flash Point: 135 °F Source: The National Institute for Occupational Safety and Health (NIOSH)

LogP: 0.46 (estimated) Source: ILO-WHO International Chemical Safety Cards (ICSCs)

Melting Point: -148 °F (NTP, 1992) Source: CAMEO Chemicals
Melting Point: FREEZING POINT: FORMS GLASS @ -100 °C Source: Hazardous Substances Data Bank (HSDB)
Melting Point: -100 °C Source: ILO-WHO International Chemical Safety Cards (ICSCs)
Melting Point: -148 °F [forms glass] Source: Occupational Safety and Health Administration (OSHA)
Melting Point: -148 °F [forms glass] Source: The National Institute for Occupational Safety and Health (NIOSH)

Odor: CHARACTERISTIC, NOT UNPLEASANT ODOR Source: Hazardous Substances Data Bank (HSDB)
Odor: ... Pleasant odor. Source: Hazardous Substances Data Bank (HSDB)

Physical Description: Allyl glycidyl ether appears as a colorless liquid with a pleasant odor. Slightly less dense than water and insoluble in water. Hence floats on water. Poisonous by ingestion and mildly toxic by inhalation and skin contact. Very irritating to skin and eyes. Used to make other chemicals. Source: CAMEO Chemicals
Physical Description: Liquid Source: EPA Chemical Data Reporting (CDR)
Physical Description: Colorless liquid with a pleasant odor; [NIOSH] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
Physical Description: COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR. Source: ILO-WHO International Chemical Safety Cards (ICSCs)
Physical Description: Colorless liquid with a pleasant odor. Source: Occupational Safety and Health Administration (OSHA)
Physical Description: Colorless liquid with a pleasant odor. Source: The National Institute for Occupational Safety and Health (NIOSH)

Refractive Index: INDEX OF REFRACTION: 1.4348 @ 20 °C Source: Hazardous Substances Data Bank (HSDB)

Solubility: greater than or equal to 100 mg/mL at 65.3 °F (NTP, 1992) Source: CAMEO Chemicals
Solubility: 14.1% IN WATER; MISCIBLE WITH ACETONE, TOLUENE, & OCTANE Source: Hazardous Substances Data Bank (HSDB)
Solubility: Solubility in water, g/100ml: 14 (freely soluble) Source: ILO-WHO International Chemical Safety Cards (ICSCs)
Solubility: 14% Source: The National Institute for Occupational Safety and Health (NIOSH)

Vapor Pressure: 3.6 mmHg at 68 °F ; 5.8 mmHg at 86 °F (NTP, 1992) Source: CAMEO Chemicals
Vapor Pressure: 4.7 [mmHg] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
Vapor Pressure: 4.7 MM HG AT 25 °C Source: Hazardous Substances Data Bank (HSDB)
Vapor Pressure: Vapor pressure, kPa at 25 °C: 0.63 Source: ILO-WHO International Chemical Safety Cards (ICSCs)
Vapor Pressure: 2 mmHg Source: Occupational Safety and Health Administration (OSHA)
Vapor Pressure: 2 mmHg Source: The National Institute for Occupational Safety and Health (NIOSH)

Substance: Allyl Glycidyl Ether Source: NTP Technical Reports
NTP Technical Report: TR-376: Toxicology and Carcinogenesis Studies of Allyl Glycidyl Ether (CASRN 106-92-3) in Osborne-Mendel Rats and B6C3F1 Mice (Inhalation Studies) (1990 ) Source: NTP Technical Reports
Peer Review Date: 06/27/89 Source: NTP Technical Reports
Conclusion for Male Rat: Equivocal Evidence Source: NTP Technical Reports
Conclusion for Female Rat: No Evidence Source: NTP Technical Reports
Conclusion for Male Mice: Some Evidence Source: NTP Technical Reports
Conclusion for Female Mice: Equivocal Evidence Source: NTP Technical Reports
Summary: Under the conditions of these 2-year inhalation studies, there was equivocal evidence of carcinogenic activity of allyl glycidyl ether for male Osborne-Mendel rats, based on the presence of one papillary adenoma of respiratory epithelial origin, one squamous cell carcinoma of respiratory epithelial origin, and one poorly differentiated adenocarcinoma of olfactory epithelial origin, all occurring in the nasal passage of males exposed to 10 ppm. There was no evidence of carcinogenic activity of allyl glycidyl ether for female rats. One papillary adenoma of the respiratory epithelium was present in a female rat exposed to 5 ppm. There was some evidence of carcinogenic activity of allyl glycidyl ether for male B6C3F1 mice, based on the presence of three adenomas of the respiratory epithelium, dysplasia in four males, and focal basal cell hyperplasia of the respiratory epithelium in seven males in the nasal passage of mice exposed to 10 ppm. There was equivocal evidence of carcinogenic activity of allyl glycidyl ether for female mice, based on the presence of one adenoma of the respiratory epithelium and focal basal cell hyperplasia of the respiratory epithelium in seven females exposed Source: NTP Technical Reports

Exposure Routes: The substance can be absorbed into the body by inhalation, through the skin and by ingestion. Source: ILO-WHO International Chemical Safety Cards (ICSCs)
Exposure Routes: inhalation, skin absorption, ingestion, skin and/or eye contact Source: The National Institute for Occupational Safety and Health (NIOSH)

First Aid: EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.; SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. IMMEDIATELY call a hospital or poison control center even if no symptoms (such as redness or irritation) develop. IMMEDIATELY transport the victim to a hospital for treatment after washing the affected areas.; INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop. Provide proper respiratory protection to rescuers entering an unknow Source: CAMEO Chemicals
ERG2024, Guide 129 (Allyl glycidyl ether): General First Aid:; · Call 911 or emergency medical service.; · Ensure that medical personnel are aware of the material(s) involved, take precautions to protect themselves and avoid contamination.; · Move victim to fresh air if it can be done safely.; · Administer oxygen if breathing is difficult.; · If victim is not breathing:; -- DO NOT perform mouth-to-mouth resuscitation; the victim may have ingested or inhaled the substance.; -- If equipped and pulse detected, wash face and mouth, then give artificial respiration using a proper respiratory medical device (bag-valve mask, pocket mask equipped with a one-way valve or other device).; -- If no pulse detected or no respiratory medical device available, provide continuous compressions. Conduct a pulse check every two minutes or monitor for any signs of spontaneous respirations.; · Remove and isolate contaminated clothing and shoes.; · For minor skin contact, avoid spreading material on unaffected skin.; · In case of contact with substance, remove immediately by flushing skin or eyes with running water for at least 20 minutes.; · For severe burns, immediate medical attention is required.; · Effects of exposure (inhalation, ingestion, Source: Emergency Response Guidebook (ERG)
First Aid: (General first aid procedures); Eye: Irrigate immediately - If this chemical contacts the eyes, immediately wash (irrigate) the eyes with large amounts of water, occasionally lifting the lower and upper lids. Get medical attention immediately.; Skin: Water flush promptly - If this chemical contacts the skin, flush the contaminated skin with water promptly. If this chemical penetrates the clothing, immediately remove the clothing and flush the skin with water promptly. If irritation persists after washing, get medical attention.; Breathing: Respiratory support; Swallow: Medical attention immediately - If this chemical has been swallowed, get medical attention immediately. Source: The National Institute for Occupational Safety and Health (NIOSH)

Signal: Danger Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
GHS Hazard Statements: H226: Flammable liquid and vapor [Warning Flammable liquids]; H302: Harmful if swallowed [Warning Acute toxicity, oral]; H315: Causes skin irritation [Warning Skin corrosion/irritation]; H317: May cause an allergic skin reaction [Warning Sensitization, Skin]; H318: Causes serious eye damage [Danger Serious eye damage/eye irritation]; H332: Harmful if inhaled [Warning Acute toxicity, inhalation]; H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]; H341: Suspected of causing genetic defects [Warning Germ cell mutagenicity]; H351: Suspected of causing cancer [Warning Carcinogenicity]; H361f ***: Suspected of damaging fertility [Warning Reproductive toxicity]; H412: Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard] Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
Precautionary Statement Codes: P203, P210, P233, P240, P241, P242, P243, P261, P264, P264+P265, P270, P271, P272, P273, P280, P301+P317, P302+P352, P303+P361+P353, P304+P340, P305+P354+P338, P317, P318, P319, P321, P330, P332+P317, P333+P317, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement) Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
Signal: Danger Source: European Chemicals Agency (ECHA)
GHS Hazard Statements: H226 (100%): Flammable liquid and vapor [Warning Flammable liquids]; H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]; H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]; H317 (100%): May cause an allergic skin reaction [Warning Sensitization, Skin]; H318 (100%): Causes serious eye damage [Danger Serious eye damage/eye irritation]; H331 (39.5%): Toxic if inhaled [Danger Acute toxicity, inhalation]; H332 (60.3%): Harmful if inhaled [Warning Acute toxicity, inhalation]; H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]; H341 (100%): Suspected of causing genetic defects [Warning Germ cell mutagenicity]; H351 (100%): Suspected of causing cancer [Warning Carcinogenicity]; H361 (99.7%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]; H412 (96.3%): Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard] Source: European Chemicals Agency (ECHA)
Precautionary Statement Codes: P203, P210, P233, P240, P241, P242, P243, P261, P264, P264+P265, P270, P271, P272, P273, P280, P301+P317, P302+P352, P303+P361+P353, P304+P340, P305+P354+P338, P316, P317, P318, P319, P321, P330, P332+P317, P333+P317, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
ECHA C&L Notifications Summary: Aggregated GHS information provided per 375 reports by companies from 20 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
Signal: Danger Source: NITE-CMC
GHS Hazard Statements: H226: Flammable liquid and vapor [Warning Flammable liquids]; H302: Harmful if swallowed [Warning Acute toxicity, oral]; H315: Causes skin irritation [Warning Skin corrosion/irritation]; H317: May cause an allergic skin reaction [Warning Sensitization, Skin]; H318: Causes serious eye damage [Danger Serious eye damage/eye irritation]; H330: Fatal if inhaled [Danger Acute toxicity, inhalation]; H341: Suspected of causing genetic defects [Warning Germ cell mutagenicity]; H351: Suspected of causing cancer [Warning Carcinogenicity]; H361: Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]; H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure]; H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]; H402: Harmful to aquatic life [Hazardous to the aquatic environment, acute hazard]; H412: Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard] Source: NITE-CMC
Precautionary Statement Codes: P203, P210, P233, P240, P241, P242, P243, P260, P261, P264, P264+P265, P270, P271, P272, P273, P280, P284, P301+P317, P302+P352, P303+P361+P353, P304+P340, P305+P354+P338, P308+P316, P316, P317, P318, P319, P320, P321, P330, P332+P317, P333+P317, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement) Source: NITE-CMC
GHS Hazard Statements: H226: Flammable liquid and vapor [Warning Flammable liquids]; H302: Harmful if swallowed [Warning Acute toxicity, oral]; H315: Causes skin irritation [Warning Skin corrosion/irritation]; H317: May cause an allergic skin reaction [Warning Sensitization, Skin]; H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H330: Fatal if inhaled [Danger Acute toxicity, inhalation]; H341: Suspected of causing genetic defects [Warning Germ cell mutagenicity]; H361: Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]; H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure]; H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure] Source: NITE-CMC
Precautionary Statement Codes: P203, P210, P233, P240, P241, P242, P243, P260, P261, P264, P264+P265, P270, P271, P272, P280, P284, P301+P317, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P308+P316, P316, P318, P319, P320, P321, P330, P332+P317, P333+P317, P337+P317, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement) Source: NITE-CMC

Target Organs: Eyes, skin, respiratory system, blood, reproductive system Source: The National Institute for Occupational Safety and Health (NIOSH)

Consumer Uses: Monomers; Intermediate Source: EPA Chemical Data Reporting (CDR)

Industry Uses: Intermediate; Bleaching agent; Monomers Source: EPA Chemical Data Reporting (CDR)

Sources/Uses: Used as a reactive diluent and intermediate in the production of resins; [ACGIH] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
Industrial Processes with risk of exposure: Plastic Composites Manufacturing [Category: Industry] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
Uses: STABILIZER OF CHLORINATED COMPOUNDS, VINYL RESINS, RUBBER; RESIN INTERMEDIATE Source: Hazardous Substances Data Bank (HSDB)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status

Source	Result	Checked
EMBL-EBI ChEBI	No exact record	2026-08-31
NIH PubChem PUG-View	Exact match	2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Record details

Chemical name

Allyl glycidyl ether

Regulatory information

Regulation

(EC) 2009/1223

See every entry this act set

SCCS opinions

CMR

Category	Carcinogenic	Mutagenic	Reprotoxic
Cat. 2	✓	✓	✓

Key data

CAS

106-92-3

203-442-4

Annex

Entry number

997

Direct matches are limited for this record, so nearby entries from Annex II are shown as well.

Annex II 996