2-Naphthol
2-Naphthol is listed in Annex II as a prohibited substance for cosmetic products placed on the EU market.
Chemical identity and properties
2-Naphthol
2-naphthol is a naphthol carrying a hydroxy group at position 2. It has a role as an antinematodal drug, a radical scavenger, a genotoxin, a mouse metabolite, a human xenobiotic metabolite and a human urinary metabolite. — ChEBI
- IUPAC name
- naphthalen-2-ol
- Molecular formula
- C10H8O
- Molecular weight
- 144.17 g/mol
- Exact mass
- 144.057514874 Da
- XLogP3
- 2.7
- Topological polar surface area
- 20.2 Ų
- Hydrogen-bond donors
- 1
- Hydrogen-bond acceptors
- 1
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
16 more reported names
External database identifiers
- ChEBI:CHEBI:10432
- ChEMBL:CHEMBL14126
- EPA DTXSID:DTXSID5027061
- PubMed:23086075
- PubMed:23024753
- PubMed:22953779
- PubMed:22920667
- PubMed:22865759
- PubMed:22710828
- PubMed:22704829
- PubMed:22689422
- PubMed:22685563
- PubMed:22655390
- PubMed:22640884
- PubMed:22629618
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
Record details
Chemical name
2-Naphthol
Regulatory information
Identified ingredients
Key data
Inventory links for 2-Naphthol
Related records for 2-Naphthol
Direct matches are limited for this record, so nearby entries from Annex II are shown as well.
1- and 2-Naphthylamines and their salts
Naphazoline (INN) and its salts
Neostigmine and its salts (e.g. neostigmine bromide (INN))
What Annex II means for 2-Naphthol
2-Naphthol is listed as a prohibited substance under Annex II of EU Cosmetics Regulation 1223/2009 and must not be intentionally added. Article 17 separately addresses unintended small quantities that are technically unavoidable under good manufacturing practice and compatible with the Article 3 safety requirement.
Formulators must screen their ingredients and raw materials to ensure none contain this substance. Suppliers should provide documentation confirming absence when requested.
This record is linked to 1 CosIng inventory ingredient for name and identifier cross-reference. The page also surfaces 12 related annex records with overlapping identifiers, annex logic or naming patterns.
Compliance checklist
- Verify this substance is absent from all raw materials and finished formulations.
- Request absence confirmation or CoA from raw material suppliers.
- Document the screening result in the Product Information File (PIF).
Frequently asked questions
Source note for Annex II record 2-Naphthol
This page summarizes one Annex II record for 2-Naphthol from public European Commission cosmetic materials and adds linked inventory or identifier matches when available.
Use this record page to review Annex II conditions for 2-Naphthol, but confirm any final regulatory decision against the current official annex wording and source files.
Tools & next steps
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