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Annex II Entry 1744 18/06/2025

benfluralin (ISO); N-butyl-N-ethyl-α,α,α-trifluoro-2,6-dinitro-p-toluidine

benfluralin (ISO); N-butyl-N-ethyl-α,α,α-trifluoro-2,6-dinitro-p-toluidine is listed in Annex II as a prohibited substance for cosmetic products placed on the EU market.

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Prohibited substance— Annex II, EU Regulation 1223/2009
Entry: 1744

Chemical identity and properties

PubChem 2D chemical structure for CAS 1861-40-1
CAS 1861-40-1PubChem CID 2319

Benfluralin

Benfluralin is a tertiany amino compound that is 2,6-dinitro-4-(trifluoromethyl)aniline in which the hydrogens attached to the aniline nitrogen have been replaced by one ethyl and one butyl group. It is used as a pre-emergence herbicide used for the control of grass and other weeds in a range of food and non-food crops. It has a role as a herbicide and an agrochemical. It is a C-nitro compound, an organofluorine compound, a substituted aniline and a tertiary amino compound. — ChEBI

IUPAC name
N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline
Molecular formula
C13H16F3N3O4
Molecular weight
335.28 g/mol
Exact mass
335.10929049 Da
XLogP3
5.3
Topological polar surface area
94.9 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
8
Covalent units
1
Defined stereocentres
0

Also known as

BethrodineBalanBENEFINBenfluralineBenephinFlubalexBalfinBenefex
16 more reported names
BinnellBonalanQuilanBanafineCarpidorBenalanEmblemBlulanEL-110N-Butyl-2,6-dinitro-N-ethyl-4-trifluoromethylanilineN-Butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)benzenamineN-Butyl-N-ethyl-2,6-dinitro-4-trifluoromethylanilineL 54521N-Butyl-N-ethyl-alpha,alpha,alpha-trifluoro-2,6-dinitro-p-toluidinealpha,alpha,alpha-Trifluoro-2,6-dinitro-N,N-ethylbutyl-p-toluidineN-Butyl N-ethyl-2,6-dinitro-4-(trifluoromethyl)benzeneamine
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Record details

Chemical name

benfluralin (ISO); N-butyl-N-ethyl-α,α,α-trifluoro-2,6-dinitro-p-toluidine

Regulatory information

Regulation

(EU) 2025/877

See every entry this act set

Key data

CAS
1861-40-1
EC
217-465-2
Annex
II
Entry number
1744

Direct matches are limited for this record, so nearby entries from Annex II are shown as well.

Annex II 1741
Nearby record in the same annex

dibutyltin oxide

CAS: 818-08-6
EC: 212-449-1

What Annex II means for benfluralin (ISO); N-butyl-N-ethyl-α,α,α-trifluoro-2,6-dinitro-p-toluidine

benfluralin (ISO); N-butyl-N-ethyl-α,α,α-trifluoro-2,6-dinitro-p-toluidine is listed as a prohibited substance under Annex II of EU Cosmetics Regulation 1223/2009 and must not be intentionally added. Article 17 separately addresses unintended small quantities that are technically unavoidable under good manufacturing practice and compatible with the Article 3 safety requirement.

Formulators must screen their ingredients and raw materials to ensure none contain this substance. Suppliers should provide documentation confirming absence when requested.

The page also surfaces 12 related annex records with overlapping identifiers, annex logic or naming patterns.

Compliance checklist

  • Verify this substance is absent from all raw materials and finished formulations.
  • Request absence confirmation or CoA from raw material suppliers.
  • Document the screening result in the Product Information File (PIF).

Frequently asked questions

Yes. benfluralin (ISO); N-butyl-N-ethyl-α,α,α-trifluoro-2,6-dinitro-p-toluidine is listed in Annex II of EU Cosmetics Regulation 1223/2009 and is prohibited as an intentionally added cosmetic ingredient. Article 17 provides a narrow exception for unintended small quantities that are technically unavoidable under good manufacturing practice, provided the product remains safe under Article 3.

CAS 1861-40-1 is the unique numerical identifier assigned to benfluralin (ISO); N-butyl-N-ethyl-α,α,α-trifluoro-2,6-dinitro-p-toluidine by the Chemical Abstracts Service. In cosmetic compliance work, the CAS number is used to cross-reference the substance across regulatory databases, raw material specifications and safety assessment reports. Multiple EU annex entries may share the same CAS number if the same substance appears under different conditions or in different annexes.

Use the INCI Checker tool on this site to paste your full ingredient list (INCI) and scan it against all Annex II–VI entries. The tool highlights any ingredients that match restricted, prohibited or allergen-flagged records. This is useful for rapid compliance screening of finished product formulas or raw material declarations.
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Source note for Annex II record benfluralin (ISO); N-butyl-N-ethyl-α,α,α-trifluoro-2,6-dinitro-p-toluidine

This page summarizes one Annex II record for benfluralin (ISO); N-butyl-N-ethyl-α,α,α-trifluoro-2,6-dinitro-p-toluidine from public European Commission cosmetic materials and adds linked inventory or identifier matches when available.

Use this record page to review Annex II conditions for benfluralin (ISO); N-butyl-N-ethyl-α,α,α-trifluoro-2,6-dinitro-p-toluidine, but confirm any final regulatory decision against the current official annex wording and source files.

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