Skip to main content
CosIng Checker
CosIng Checker
EU cosmetic ingredients, restrictions and safety
Login
Annex II Entry 1739 18/06/2025

dimethyl propylphosphonate

dimethyl propylphosphonate is listed in Annex II as a prohibited substance for cosmetic products placed on the EU market.

Search similar Back to annex Compare
Prohibited substance— Annex II, EU Regulation 1223/2009
Entry: 1739

Chemical identity and properties

PubChem 2D chemical structure for CAS 18755-43-6
CAS 18755-43-6PubChem CID 87779

Dimethyl propylphosphonate

IUPAC name
1-dimethoxyphosphorylpropane
Molecular formula
C5H13O3P
Molecular weight
152.13 g/mol
Exact mass
152.06023127 Da
XLogP3
0.4
Topological polar surface area
35.5 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
3
Covalent units
1
Defined stereocentres
0

Also known as

Phosphonic acid, P-propyl-, dimethyl esterEINECS 242-555-3dimethyl n-propylphosphonateDimethyl-n-propylphosphonateEC 242-555-3Propylphosphonic acid, dimethyl ester242-555-3RefChem:134268
9 more reported names
YWDFOLFVOVCBIU-UHFFFAOYSA-Ndimethylpropyl phosphonatePhosphonic acid, propyl-, dimethyl esterAvibactam Impurity 34P-Popylphosphonic Acid Dimethyl Ester; Dimethyl Propanephosphonate; Lavagard DMPP;propanephosphonic acid dimethyl esterdimethylpropanphosphonate62C4FYU7CEdimethyl propylphosphonate;phosphonic acid, propyl-, dimethyl ester;dimethyl propylphosphonate phosphonic acid, propyl-, dimethyl ester
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Record details

Chemical name

dimethyl propylphosphonate

Regulatory information

Regulation

(EU) 2025/877

See every entry this act set

Key data

CAS
18755-43-6
EC
242-555-3
Annex
II
Entry number
1739

Direct matches are limited for this record, so nearby entries from Annex II are shown as well.

Annex II 1741
Nearby record in the same annex

dibutyltin oxide

CAS: 818-08-6
EC: 212-449-1

What Annex II means for dimethyl propylphosphonate

dimethyl propylphosphonate is listed as a prohibited substance under Annex II of EU Cosmetics Regulation 1223/2009 and must not be intentionally added. Article 17 separately addresses unintended small quantities that are technically unavoidable under good manufacturing practice and compatible with the Article 3 safety requirement.

Formulators must screen their ingredients and raw materials to ensure none contain this substance. Suppliers should provide documentation confirming absence when requested.

The page also surfaces 12 related annex records with overlapping identifiers, annex logic or naming patterns.

Compliance checklist

  • Verify this substance is absent from all raw materials and finished formulations.
  • Request absence confirmation or CoA from raw material suppliers.
  • Document the screening result in the Product Information File (PIF).

Frequently asked questions

Yes. dimethyl propylphosphonate is listed in Annex II of EU Cosmetics Regulation 1223/2009 and is prohibited as an intentionally added cosmetic ingredient. Article 17 provides a narrow exception for unintended small quantities that are technically unavoidable under good manufacturing practice, provided the product remains safe under Article 3.

CAS 18755-43-6 is the unique numerical identifier assigned to dimethyl propylphosphonate by the Chemical Abstracts Service. In cosmetic compliance work, the CAS number is used to cross-reference the substance across regulatory databases, raw material specifications and safety assessment reports. Multiple EU annex entries may share the same CAS number if the same substance appears under different conditions or in different annexes.

Use the INCI Checker tool on this site to paste your full ingredient list (INCI) and scan it against all Annex II–VI entries. The tool highlights any ingredients that match restricted, prohibited or allergen-flagged records. This is useful for rapid compliance screening of finished product formulas or raw material declarations.
Open INCI Checker

Source note for Annex II record dimethyl propylphosphonate

This page summarizes one Annex II record for dimethyl propylphosphonate from public European Commission cosmetic materials and adds linked inventory or identifier matches when available.

Use this record page to review Annex II conditions for dimethyl propylphosphonate, but confirm any final regulatory decision against the current official annex wording and source files.

View sourcesView updates

Tools & next steps

Check your formula

Paste a full INCI list to detect dimethyl propylphosphonate and other flagged EU annex records in one pass.

INCI Checker

Compare entries

Compare dimethyl propylphosphonate side by side with another annex record to review differences in restrictions, concentrations and annex placement.

Compare

Browse the annex

See all records in Annex II and compare regulatory conditions across substances in this annex.

Open Annex II