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RestrictedBinding ruleSAOriginal is EnglishOfficial-source import checked

1-(beta-Hydroxyethyl)amino-2-nitro-4-N-ethyl-N-(beta-hydroxyethyl)aminobenzene and its hydrocloride

Listed by the Saudi Food and Drug Authority as restricted in cosmetic products; open the cited detail for the current conditions.

All Saudi Arabia recordsOpen ingredient profileCompare all marketsOpen official source

Regulatory decision and full conditions

Status
Restricted
Legal role
Binding rule
Regulatory summary
Listed by the Saudi Food and Drug Authority as restricted in cosmetic products; open the cited detail for the current conditions.
Conditions and restrictions
If this row does not reproduce conditions, open the cited official detail because omission does not mean unrestricted use. Open the cited source and apply the market-wide requirements below.

Substance identity

Official source name
1-(beta-Hydroxyethyl)amino-2-nitro-4-N-ethyl-N-(beta-hydroxyethyl)aminobenzene and its hydrocloride
CAS
104516-93-0; 132885-85-9
EC
Not supplied in this source row
Identity mapping
Exact CAS: 104516-93-0
Linked ingredient
HC BLUE NO. 12
Search this identity across the siteCAS 104516-93-0CAS 132885-85-9

Linked CosIng identity data

Names and aliases

HC BLUE NO. 12

CosIng description: 4-[N-Ethyl-N-(2-hydroxyethyl)amino]-1-(2-hydroxyethyl)amino-2-nitrobenzene, monohydrochloride

EU inventory restriction note: III/225

Recorded cosmetic function: HAIR DYEING

Function pages:HAIR DYEING

View the complete ingredient profile

Cross-market snapshot for this identity

Exact linked records currently present in this site. An absent market means no imported exact match, not permission to use the substance.

6 market datasets
PubChem 2D chemical structure for CAS 104516-93-0
CAS 104516-93-0PubChem CID 11140152

Verified chemistry for CAS 104516-93-0

Ethanol, 2-[[4-[ethyl(2-hydroxyethyl)amino]-2-nitrophenyl]amino]-

IUPAC name
2-[4-[ethyl(2-hydroxyethyl)amino]-2-nitroanilino]ethanol
Molecular formula
C12H19N3O4
Molecular weight
269.30 g/mol
Exact mass
269.13755610 Da
Monoisotopic mass
269.13755610 Da
XLogP3
1.4
Topological polar surface area
102.0 Ų
Molecular complexity
272.0
Formal charge
0
Hydrogen-bond donors
3
Hydrogen-bond acceptors
6
Rotatable bonds
7
Heavy atoms
19
Covalent units
1

Names and synonyms reported to PubChem

Ethanol, 2-4-ethyl(2-hydroxyethyl)amino-2-nitrophenylamino-Ethanol, 2-((4-(ethyl(2-hydroxyethyl)amino)-2-nitrophenyl)amino)-RefChem:592150600-575-3Ethanol,2-[[4-[ethyl(2-hydroxyethyl)amino]-2-nitrophenyl]amino]-SSRBPSAPLFYFAX-UHFFFAOYSA-N2-{4-[Ethyl(2-hydroxyethyl)amino]-2-nitroanilino}ethan-1-ol
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D pharmacophore features
11
3D rings
1
3D hydrophobes
0
3D acceptor features
4
3D donor features
3
3D anionic centres
1
3D cationic centres
2
3D conformers
10
Effective 3D rotors
8.0
Machine-readable structure identifiers
SMILES
CCN(CCO)C1=CC(=C(C=C1)NCCO)[N+](=O)[O-]
InChI
InChI=1S/C12H19N3O4/c1-2-14(6-8-17)10-3-4-11(13-5-7-16)12(9-10)15(18)19/h3-4,9,13,16-17H,2,5-8H2,1H3
InChIKey
SSRBPSAPLFYFAX-UHFFFAOYSA-N

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match11140152

Attributed physical-property, hazard, environmental and use annotations.

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
EMBL-EBI ChEBINo exact record2026-08-31
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 132885-85-9
CAS 132885-85-9PubChem CID 21909533

Verified chemistry for CAS 132885-85-9

HC Blue 12

IUPAC name
2-[4-[ethyl(2-hydroxyethyl)amino]-2-nitroanilino]ethanol;hydrochloride
Molecular formula
C12H20ClN3O4
Molecular weight
305.76 g/mol
Exact mass
305.1142338 Da
Monoisotopic mass
305.1142338 Da
Topological polar surface area
102.0 Ų
Molecular complexity
272.0
Formal charge
0
Hydrogen-bond donors
4
Hydrogen-bond acceptors
6
Rotatable bonds
7
Heavy atoms
20
Covalent units
2

Names and synonyms reported to PubChem

4-[N-ethyl-N-(2-hydroxyethyl)amino]-1-(2-hydroxyethyl)amino-2-nitrobenzene, monohydrochloride4-(N-ethyl-N-(2-hydroxyethyl)amino)-1-(2-hydroxyethyl)amino-2-nitrobenzene, monohydrochlorideRefChem:1086372Ethanol, 2-((4-(ethyl(2-hydroxyethyl)amino)-2-nitrophenyl)amino)-, hydrochloride (1:1)407-020-22-((4-(Ethyl(2-hydroxyethyl)amino)-2-nitrophenyl)amino)ethan-1-ol hydrochlorideEC 407-020-2Nitroblau
9 more reported names
HC Azul 12HC Bleu 12HC Blu 12COLIPA n degrees B73HC BLUE NO. 12LXKQJEXWFGAMMW-UHFFFAOYSA-N2-[[4-[ethyl(2-hydroxyethyl)amino]-2-nitrophenyl]amino]ethanol hydrochloride2-{4-[Ethyl(2-hydroxyethyl)amino]-2-nitroanilino}ethan-1-ol--hydrogen chloride (1/1)Ethanol, 2-a[[4-a[ethyl(2-ahydroxyethyl)aamino]a-a2-anitrophenyl]aamino]a-a, hydrochloride (1:1)
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D conformers
0
Machine-readable structure identifiers
SMILES
CCN(CCO)C1=CC(=C(C=C1)NCCO)[N+](=O)[O-].Cl
InChI
InChI=1S/C12H19N3O4.ClH/c1-2-14(6-8-17)10-3-4-11(13-5-7-16)12(9-10)15(18)19;/h3-4,9,13,16-17H,2,5-8H2,1H3;1H
InChIKey
LXKQJEXWFGAMMW-UHFFFAOYSA-N

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Official source and provenance

Registered source
Saudi SFDA prohibited and restricted ingredient lists
Source reference
SFDA restricted list, page 23, row 2
Source record ID
restricted-22-2
Source version
live-snapshot-2026-08-30
Source language
English
Translation status
Original is English
Snapshot checked
2026-08-30 05:18 UTC
Validation method
complete SFDA paginated HTML snapshot; strict page/row counts
SHA-256
ceb6cc636e6b1f4b3013f88ce0297217b49d6194342c6ece5c03b1e04256d71a

Registered dataset notes

Dataset coverage
Prohibited and restricted substances with CAS, EC and conditions
Authority note
Official SFDA dated lists; version and hash each release
Inspect the exact official sourceRegulator guidance

How this record fits the market dataset

2090
current Saudi Arabia records
364
records marked Restricted
2090
records from this source version
1991
market records with CAS identity

Status distribution

Prohibited: 1726Restricted: 364

Condition text is present on 0 of 2090 current records. An empty condition field is interpreted according to the record type above; it is never converted into an unrestricted-use claim.

Saudi Arabia market context

Complete official list index

Coverage version: SFDA live prohibited/restricted lists, snapshot 30 August 2026

Every page and entry in the public SFDA prohibited and restricted ingredient indexes; restricted detail pages remain the source for conditions.

Verification checklist

  1. Search names and CAS across both SFDA lists.
  2. Open the cited restricted-entry detail and apply every condition.
  3. Check current SFDA/GSO technical regulations and updates.
  4. Complete eCosma notification, label and responsible-party requirements.

Official market sources

Verification workflow and record completeness

Before using this result in a compliance decision

  1. Confirm that “1-(beta-Hydroxyethyl)amino-2-nitro-4-N-ethyl-N-(beta-hydroxyethyl)aminobenzene and its hydrocloride” and every CAS/EC identifier refer to the material in your supplier specification.
  2. Search names and CAS across both SFDA lists.
  3. Open the cited restricted-entry detail and apply every condition.
  4. Check current SFDA/GSO technical regulations and updates.
  5. Complete eCosma notification, label and responsible-party requirements.
  6. Document the source version and recheck the regulator before manufacture, notification or market placement.

Fields available in this record

  • Official substance nameAvailable
  • CASAvailable
  • ECNot supplied
  • Separate condition textNot present in source row
  • Effective dateNot supplied
  • Snapshot hash and methodAvailable

Questions this page answers

This substance is not unrestricted: cosmetic use is subject to the conditions in the cited official record. Check product type, body area, concentration, purity and warning requirements before deciding whether a formulation is compliant.

If this row does not reproduce conditions, open the cited official detail because omission does not mean unrestricted use. No list match is not permission; Gulf/SFDA product, claim, notification and technical requirements still apply.

The record cites SFDA restricted list, page 23, row 2, source version live-snapshot-2026-08-30. Open the official source.

No. CAS helps resolve identity, but jurisdictions can classify the same substance differently and can apply different product scopes, limits, warnings and transition dates.

Stable citation

1-(beta-Hydroxyethyl)amino-2-nitro-4-N-ethyl-N-(beta-hydroxyethyl)aminobenzene and its hydrocloride. SFDA restricted list, page 23, row 2. Saudi Arabia. Source version live-snapshot-2026-08-30. CosIng Checker regulatory record: https://cosingchecker.com/regulations/sa/records/11547/

Cite the regulator as the legal authority. This page is a structured evidence index and verification aid, not a substitute for the official text or professional legal assessment.

Interpretation and limits for Saudi Arabia

This substance is not unrestricted: cosmetic use is subject to the conditions in the cited official record.

Check product type, body area, concentration, purity and warning requirements before deciding whether a formulation is compliant.

How to interpret the legal role

The cited row forms part of a binding rule or legally incorporated list for this market.

Evidence on this page

  • Recorded outcome: Restricted
  • Legal role: Binding rule
  • Source version: live-snapshot-2026-08-30

What it does not prove

No list match is not permission; Gulf/SFDA product, claim, notification and technical requirements still apply.

Further authoritative substance research

These sources can add identity, safety, exposure or hazard context. A link is not evidence that the database contains this exact substance, and none of these sources overrides the market decision above.

Cosmetic Ingredient Review safety assessments

Expert Panel conclusions, assessed ingredient groups, use conditions, dates and report documents

Independent expert review considered by FDA; not a government approval or binding market rule

Research this identity at the source

FDA Global Substance Registration System

UNII identifiers, preferred names, substance types, codes and public substance relationships

Identity registry only; UNII availability does not imply FDA review or approval

Research this identity at the source

ILO/WHO International Chemical Safety Cards

Hazards, symptoms, first aid, storage, incompatibilities and physical properties for covered chemicals

International occupational chemical-safety reference; not cosmetic-use approval

Research this identity at the source

Japan NITE-CHRIP

Chemical identity, Japanese and foreign legal lists, GHS hazards and exposure-related information

Chemical-management evidence; cosmetic status remains governed by the applicable MHLW standard and market rules

Research this identity at the source

NIOSH Pocket Guide to Chemical Hazards

REL, PEL, IDLH, properties, exposure routes, symptoms, target organs, first aid and measurement methods for covered workplace chemicals

US occupational-health guidance and limits; not a cosmetic ingredient decision

Research this identity at the source

OECD eChemPortal

Gateway to authority-owned physical-property, fate, ecotoxicity, toxicity, exposure and GHS records

Discovery gateway; each linked authority remains responsible for its data

Research this identity at the source

US EPA CompTox CTX APIs

API key required for import

DTXSID identity, experimental and predicted properties, toxicity, bioactivity, exposure and environmental data

Scientific and computational evidence; predictions must remain labelled and do not determine cosmetic legality

Research this identity at the source