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RestrictedBinding ruleKRNo English translationOfficial-source import checked

2-클로로-6-에칠아미노-4-니트로페놀 및 그 염류

Listed by the Korean MFDS as a cosmetic ingredient requiring conditions of use.

All South Korea recordsOpen ingredient profileCompare all marketsOpen official source

Regulatory decision and full conditions

Status
Restricted
Legal role
Binding rule
Regulatory summary
Listed by the Korean MFDS as a cosmetic ingredient requiring conditions of use.
Conditions and restrictions
·산화염모제에 1.5% ·비산화염모제에 3.0% · 기타제품에는 사용금지 · 2-클로로-6-에칠아미노-4-니트로페놀

Substance identity

Official source name
2-클로로-6-에칠아미노-4-니트로페놀 및 그 염류
CAS
131657-78-8
EC
411-440-1
Identity mapping
cas_number
Linked ingredient
2-CHLORO-6-ETHYLAMINO-4-NITROPHENOL
Search this identity across the siteCAS 131657-78-8EC 411-440-1

Linked CosIng identity data

Names and aliases

2-CHLORO-6-ETHYLAMINO-4-NITROPHENOL

CosIng description: Phenol, 2-chloro-6-(ethylamino)-4-nitro-

EU inventory restriction note: III/201

Recorded cosmetic function: HAIR DYEING

Function pages:HAIR DYEING

View the complete ingredient profile

Cross-market snapshot for this identity

Exact linked records currently present in this site. An absent market means no imported exact match, not permission to use the substance.

7 market datasets

South Korea

Current record
ProhibitedRestricted

2 linked records · 2 with specific conditions

Open supporting record
PubChem 2D chemical structure for CAS 131657-78-8
CAS 131657-78-8PubChem CID 9794399

Verified chemistry for CAS 131657-78-8

2-Chloro-6-(ethylamino)-4-nitrophenol

IUPAC name
2-chloro-6-(ethylamino)-4-nitrophenol
Molecular formula
C8H9ClN2O3
Molecular weight
216.62 g/mol
Exact mass
216.0301698 Da
Monoisotopic mass
216.0301698 Da
XLogP3
2.7
Topological polar surface area
78.1 Ų
Molecular complexity
209.0
Formal charge
0
Hydrogen-bond donors
2
Hydrogen-bond acceptors
4
Rotatable bonds
2
Heavy atoms
14
Covalent units
1

Names and synonyms reported to PubChem

2-CHLORO-6-ETHYLAMINO-4-NITROPHENOL6-Chloro-2-(ethylamino)-4-nitrophenolUNII-5LIV96LADQ5LIV96LADQPhenol, 2-chloro-6-(ethylamino)-4-nitro-2-Chloro-6-ethylamino-4-nitrophenol [INCI]EC 411-440-1RefChem:86320
7 more reported names
411-440-1CDFNUSAXZDSXKF-UHFFFAOYSA-NBS-496816-Chloro-2-(N-Ethyl)Amino-4-Nitrophenol2-chloranyl-6-(ethylamino)-4-nitro-phenolDB-062839CS-0151978
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D pharmacophore features
7
3D rings
1
3D hydrophobes
0
3D acceptor features
2
3D donor features
2
3D anionic centres
1
3D cationic centres
1
3D conformers
2
Effective 3D rotors
3.0
Machine-readable structure identifiers
SMILES
CCNC1=C(C(=CC(=C1)[N+](=O)[O-])Cl)O
InChI
InChI=1S/C8H9ClN2O3/c1-2-10-7-4-5(11(13)14)3-6(9)8(7)12/h3-4,10,12H,2H2,1H3
InChIKey
CDFNUSAXZDSXKF-UHFFFAOYSA-N

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Official source and provenance

Registered source
South Korea MFDS cosmetic ingredient data
Source reference
화장품 안전기준 등에 관한 규정, 별표 2, record 2-240
Source record ID
2-240
Source version
2026-19
Source language
Korean
Translation status
No English translation
Effective date
2026-03-18
Source updated
2026-03-18
Snapshot checked
2026-08-30 04:33 UTC
Validation method
MFDS JSON appendices 1–2 parse; 1077 prohibited, 243 restricted
SHA-256
056de35b843a5e31f709073f9e79d5e6e18f7c9164eb537bb099b185a37ef7d8

Registered dataset notes

Dataset coverage
Ingredient identity and separate restriction/regulation data endpoints
Authority note
Korean source is canonical; English materials alone are not complete enough for certification
Inspect the exact official sourceRegulator guidance

How this record fits the market dataset

1320
current South Korea records
243
records marked Restricted
1320
records from this source version
1252
market records with CAS identity

Status distribution

Prohibited: 1077Restricted: 243

Condition text is present on 638 of 1320 current records. An empty condition field is interpreted according to the record type above; it is never converted into an unrestricted-use claim.

South Korea market context

Complete current appendix dataset

Coverage version: MFDS Notice 2026-19, effective 18 March 2026

All rows in official Appendix 1 (prohibited) and Appendix 2 (restricted) of the Safety Standards for Cosmetics.

Verification checklist

  1. Match the Korean canonical substance name and identifiers.
  2. Review all Appendix 1 and 2 matches and conditions.
  3. Check functional-cosmetic and positive-list requirements where applicable.
  4. Confirm current MFDS notice, responsible seller and label obligations.

Official market sources

Verification workflow and record completeness

Before using this result in a compliance decision

  1. Confirm that “2-클로로-6-에칠아미노-4-니트로페놀 및 그 염류” and every CAS/EC identifier refer to the material in your supplier specification.
  2. Match the Korean canonical substance name and identifiers.
  3. Review all Appendix 1 and 2 matches and conditions.
  4. Check functional-cosmetic and positive-list requirements where applicable.
  5. Confirm current MFDS notice, responsible seller and label obligations.
  6. Document the source version and recheck the regulator before manufacture, notification or market placement.

Fields available in this record

  • Official substance nameAvailable
  • CASAvailable
  • ECAvailable
  • Separate condition textAvailable
  • Effective dateAvailable
  • Snapshot hash and methodAvailable

Questions this page answers

This substance is not unrestricted: cosmetic use is subject to the conditions in the cited official record. Check product type, body area, concentration, purity and warning requirements before deciding whether a formulation is compliant.

If this row does not reproduce conditions, open the cited official detail because omission does not mean unrestricted use. Korean source wording is canonical and other positive lists/notices may still apply to the formulation.

The record cites 화장품 안전기준 등에 관한 규정, 별표 2, record 2-240, source version 2026-19. Open the official source.

No. CAS helps resolve identity, but jurisdictions can classify the same substance differently and can apply different product scopes, limits, warnings and transition dates.

Stable citation

2-클로로-6-에칠아미노-4-니트로페놀 및 그 염류. 화장품 안전기준 등에 관한 규정, 별표 2, record 2-240. South Korea. Source version 2026-19. CosIng Checker regulatory record: https://cosingchecker.com/regulations/kr/records/2047/

Cite the regulator as the legal authority. This page is a structured evidence index and verification aid, not a substitute for the official text or professional legal assessment.

Interpretation and limits for South Korea

This substance is not unrestricted: cosmetic use is subject to the conditions in the cited official record.

Check product type, body area, concentration, purity and warning requirements before deciding whether a formulation is compliant.

How to interpret the legal role

The cited row forms part of a binding rule or legally incorporated list for this market.

Evidence on this page

  • Recorded outcome: Restricted
  • Legal role: Binding rule
  • Source version: 2026-19
  • Effective date: 2026-03-18

What it does not prove

Korean source wording is canonical and other positive lists/notices may still apply to the formulation.

Further authoritative substance research

These sources can add identity, safety, exposure or hazard context. A link is not evidence that the database contains this exact substance, and none of these sources overrides the market decision above.

Cosmetic Ingredient Review safety assessments

Expert Panel conclusions, assessed ingredient groups, use conditions, dates and report documents

Independent expert review considered by FDA; not a government approval or binding market rule

Research this identity at the source

FDA Global Substance Registration System

UNII identifiers, preferred names, substance types, codes and public substance relationships

Identity registry only; UNII availability does not imply FDA review or approval

Research this identity at the source

ILO/WHO International Chemical Safety Cards

Hazards, symptoms, first aid, storage, incompatibilities and physical properties for covered chemicals

International occupational chemical-safety reference; not cosmetic-use approval

Research this identity at the source

Japan NITE-CHRIP

Chemical identity, Japanese and foreign legal lists, GHS hazards and exposure-related information

Chemical-management evidence; cosmetic status remains governed by the applicable MHLW standard and market rules

Research this identity at the source

NIOSH Pocket Guide to Chemical Hazards

REL, PEL, IDLH, properties, exposure routes, symptoms, target organs, first aid and measurement methods for covered workplace chemicals

US occupational-health guidance and limits; not a cosmetic ingredient decision

Research this identity at the source

OECD eChemPortal

Gateway to authority-owned physical-property, fate, ecotoxicity, toxicity, exposure and GHS records

Discovery gateway; each linked authority remains responsible for its data

Research this identity at the source

US EPA CompTox CTX APIs

API key required for import

DTXSID identity, experimental and predicted properties, toxicity, bioactivity, exposure and environmental data

Scientific and computational evidence; predictions must remain labelled and do not determine cosmetic legality

Research this identity at the source