Phenyl salicylate
Japan Standards for Cosmetics: Phenyl salicylate
The provisional English translation of the MHLW Standards for Cosmetics lists this ingredient with the stated limit or use matrix.
Regulatory decision and full conditions
- Status
- Restricted
- Legal role
- Binding rule
- Regulatory summary
- The provisional English translation of the MHLW Standards for Cosmetics lists this ingredient with the stated limit or use matrix.
- Conditions and restrictions
- Maximum amount per 100 g: 1.0 g
Substance identity
- Official source name
- Phenyl salicylate
- CAS
- 118-55-8
- EC
- 204-259-2
- Identity mapping
- exact INCI name
- Linked ingredient
- PHENYL SALICYLATE
Linked CosIng identity data
Names and aliases
CosIng description: Benzoic acid, 2-hydroxy-, phenyl ester
Recorded cosmetic function: ANTIMICROBIAL, DENATURANT, PERFUMING
Function pages:ANTIMICROBIAL, DENATURANT, PERFUMING
View the complete ingredient profileCross-market snapshot for this identity
Exact linked records currently present in this site. An absent market means no imported exact match, not permission to use the substance.
Japan
Current record1 linked record · 1 with specific conditions
Open supporting recordSouth Korea
1 linked record
Open supporting recordVerified chemistry for CAS 118-55-8
Phenyl Salicylate
- IUPAC name
- phenyl 2-hydroxybenzoate
- Molecular formula
- C13H10O3
- Molecular weight
- 214.22 g/mol
- Exact mass
- 214.062994177 Da
- Monoisotopic mass
- 214.062994177 Da
- XLogP3
- 3.8
- Topological polar surface area
- 46.5 Ų
- Molecular complexity
- 233.0
- Formal charge
- 0
- Hydrogen-bond donors
- 1
- Hydrogen-bond acceptors
- 3
- Rotatable bonds
- 3
- Heavy atoms
- 16
- Covalent units
- 1
Names and synonyms reported to PubChem
16 more reported names
External database identifiers
- ChEBI:CHEBI:34918
- ChEMBL:CHEMBL1339216
- EPA DTXSID:DTXSID6021957
- PubMed:26321725
- PubMed:24004914
- PubMed:23015476
- PubMed:22432444
- PubMed:22197706
- PubMed:21589569
- PubMed:21389553
- PubMed:21333302
- PubMed:20673861
- PubMed:20524703
- PubMed:20365736
- PubMed:19449852
Advanced structure statistics
- Defined atom stereocentres
- 0
- Undefined atom stereocentres
- 0
- Defined bond stereocentres
- 0
- Undefined bond stereocentres
- 0
- 3D pharmacophore features
- 4
- 3D rings
- 2
- 3D hydrophobes
- 0
- 3D acceptor features
- 1
- 3D donor features
- 1
- 3D anionic centres
- 0
- 3D cationic centres
- 0
- 3D conformers
- 10
- Effective 3D rotors
- 3.0
Machine-readable structure identifiers
- SMILES
C1=CC=C(C=C1)OC(=O)C2=CC=CC=C2O- InChI
InChI=1S/C13H10O3/c14-12-9-5-4-8-11(12)13(15)16-10-6-2-1-3-7-10/h1-9,14H- InChIKey
ZQBAKBUEJOMQEX-UHFFFAOYSA-N
Evidence from additional scientific databases
NIH PubChem PUG-View
Attributed physical-property, hazard, environmental and use annotations.
- Boiling Point: 172-173 Source: DrugBank
- Boiling Point: 172.00 to 173.00 °C. @ 12.00 mm Hg Source: Human Metabolome Database (HMDB)
- Boiling Point: 172-173 °C (12 mm Hg) Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- Melting Point: 41-43 Source: DrugBank
- Melting Point: 43 °C Source: Human Metabolome Database (HMDB)
- Physical Description: Dry Powder Source: EPA Chemical Data Reporting (CDR)
- Physical Description: White solid with a pleasant odor; [Merck Index] White crystals; [Sigma-Aldrich MSDS] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Physical Description: Solid Source: Human Metabolome Database (HMDB)
- Physical Description: White crystalline solid Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- Solubility: insoluble Source: DrugBank
- Solubility: 0.15 mg/mL at 25 °C Source: Human Metabolome Database (HMDB)
- Solubility: insoluble in water; soluble in 50% Heptane Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- Solubility: moderately soluble (in ethanol) Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- Vapor Pressure: 0.00000817 [mmHg] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Carcinogen Classification: No indication of carcinogenicity to humans (not listed by IARC). Source: Toxin and Toxin Target Database (T3DB)
- Note: This chemical does not meet GHS hazard criteria for 12.6% (92 of 729) of reports. Source: European Chemicals Agency (ECHA)
- Signal: Warning Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: H315 (85.9%): Causes skin irritation [Warning Skin corrosion/irritation]; H319 (84.5%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H335 (84.1%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] Source: European Chemicals Agency (ECHA)
- Precautionary Statement Codes: P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: Aggregated GHS information provided per 729 reports by companies from 14 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Reported as not meeting GHS hazard criteria per 92 of 729 reports by companies.; There are 13 notifications provided by 637 of 729 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- Industry Uses: Absorbent Source: EPA Chemical Data Reporting (CDR)
- Sources/Uses: Used to make polymers; Also used as a drug (analgesic/antipyretic/anti-inflammatory) and ingredient in lacquers, adhesives, waxes, polishes, suntan products, and plastics (absorbs light and prevents discoloration); [Merck Index] Used as an antioxidant and stabilizer/thickener for foods; [FDA] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Industrial Processes with risk of exposure: Painting (Pigments, Binders, and Biocides) [Category: Paint]; Working with Glues and Adhesives [Category: Other] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record
Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.
Additional source coverage and match status
| Source | Result | Checked |
|---|---|---|
| NIH PubChem PUG-View | Exact match | 2026-08-31 |
A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
Official source and provenance
- Registered source
- Japan MHLW Standards for Cosmetics
- Source reference
- Appendix 2 section 1, entry 3
- Source record ID
appendix-2-1:3- Source version
- MHLW Notification No. 331 provisional translation, retrieved 2026-08-30
- Source language
- English provisional translation; Japanese text is canonical
- Translation status
- Regulator-hosted provisional English translation · English translation
- Snapshot checked
- 2026-08-30 04:11 UTC
- Validation method
- pdftotext -layout plus strict per-table row counts
- SHA-256
117fc949a82789ca66017163f19041cf2fcf6b5902708077c8e4f56c482dc8e2
Registered dataset notes
- Dataset coverage
- Prohibited and restricted ingredient appendices with concentration and use conditions
- Authority note
- Official MHLW standard; validate later Japanese updates before presenting current status
How this record fits the market dataset
Status distribution
Condition text is present on 117 of 117 current records. An empty condition field is interpreted according to the record type above; it is never converted into an unrestricted-use claim.
Japan market context
Complete Standards appendices dataset
Coverage version: MHLW Standards for Cosmetics official English source and Japanese amendments checked for the imported snapshot
Prohibited ingredients, restricted ingredients and permitted preservative/UV/colourant appendices present in the official standard source.
Verification checklist
- Search Japanese/English identity and CAS where present.
- Apply category and maximum-amount conditions.
- Check later MHLW notices against the Japanese source.
- Verify marketing licence, notification, labelling and quasi-drug classification.
Official market sources
- Japan MHLW Standards for CosmeticsOfficial MHLW standard; validate later Japanese updates before presenting current status
Verification workflow and record completeness
Before using this result in a compliance decision
- Confirm that “Phenyl salicylate” and every CAS/EC identifier refer to the material in your supplier specification.
- Search Japanese/English identity and CAS where present.
- Apply category and maximum-amount conditions.
- Check later MHLW notices against the Japanese source.
- Verify marketing licence, notification, labelling and quasi-drug classification.
- Document the source version and recheck the regulator before manufacture, notification or market placement.
Fields available in this record
- Official substance nameAvailable
- CASAvailable
- ECAvailable
- Separate condition textAvailable
- Effective dateNot supplied
- Snapshot hash and methodAvailable
Questions this page answers
Stable citation
Phenyl salicylate. Appendix 2 section 1, entry 3. Japan. Source version MHLW Notification No. 331 provisional translation, retrieved 2026-08-30. CosIng Checker regulatory record: https://cosingchecker.com/regulations/jp/records/630/
Cite the regulator as the legal authority. This page is a structured evidence index and verification aid, not a substitute for the official text or professional legal assessment.
Interpretation and limits for Japan
This substance is not unrestricted: cosmetic use is subject to the conditions in the cited official record.
Check product type, body area, concentration, purity and warning requirements before deciding whether a formulation is compliant.
How to interpret the legal role
The cited row forms part of a binding rule or legally incorporated list for this market.
Evidence on this page
- Recorded outcome: Restricted
- Legal role: Binding rule
- Source version: MHLW Notification No. 331 provisional translation, retrieved 2026-08-30
What it does not prove
The Japanese text and subsequent notices are canonical; no local match is not a product-compliance conclusion.
Further authoritative substance research
These sources can add identity, safety, exposure or hazard context. A link is not evidence that the database contains this exact substance, and none of these sources overrides the market decision above.
Cosmetic Ingredient Review safety assessments
Expert Panel conclusions, assessed ingredient groups, use conditions, dates and report documents
Independent expert review considered by FDA; not a government approval or binding market rule
Research this identity at the sourceFDA Global Substance Registration System
UNII identifiers, preferred names, substance types, codes and public substance relationships
Identity registry only; UNII availability does not imply FDA review or approval
Research this identity at the sourceILO/WHO International Chemical Safety Cards
Hazards, symptoms, first aid, storage, incompatibilities and physical properties for covered chemicals
International occupational chemical-safety reference; not cosmetic-use approval
Research this identity at the sourceJapan NITE-CHRIP
Chemical identity, Japanese and foreign legal lists, GHS hazards and exposure-related information
Chemical-management evidence; cosmetic status remains governed by the applicable MHLW standard and market rules
Research this identity at the sourceNIOSH Pocket Guide to Chemical Hazards
REL, PEL, IDLH, properties, exposure routes, symptoms, target organs, first aid and measurement methods for covered workplace chemicals
US occupational-health guidance and limits; not a cosmetic ingredient decision
Research this identity at the sourceOECD eChemPortal
Gateway to authority-owned physical-property, fate, ecotoxicity, toxicity, exposure and GHS records
Discovery gateway; each linked authority remains responsible for its data
Research this identity at the sourceUS EPA CompTox CTX APIs
API key required for importDTXSID identity, experimental and predicted properties, toxicity, bioactivity, exposure and environmental data
Scientific and computational evidence; predictions must remain labelled and do not determine cosmetic legality
Research this identity at the source