Molybdenum trioxide (CAS No. 1313-27-5)
IS 4707 Part 2:2025 Annex A lists this ingredient as one that must not form part of a cosmetic product in India.
Regulatory decision and full conditions
- Status
- Prohibited
- Legal role
- Binding rule
- Regulatory summary
- IS 4707 Part 2:2025 Annex A lists this ingredient as one that must not form part of a cosmetic product in India.
- Conditions and restrictions
- Must not form part of the composition of cosmetic products. Apply the general trace and safety notes published after Annex A.
Substance identity
- Official source name
- Molybdenum trioxide (CAS No. 1313-27-5)
- CAS
- 1313-27-5
- EC
- Not supplied in this source row
- Identity mapping
- standalone:official_bis_record
Cross-market snapshot for this identity
Exact linked records currently present in this site. An absent market means no imported exact match, not permission to use the substance.
European Union
1 linked record
Open supporting recordGreat Britain
1 linked record
Open supporting recordNew Zealand
1 linked record
Open supporting recordASEAN
1 linked record
Open supporting recordIndia
Current record1 linked record · 1 with specific conditions
Open supporting recordSaudi Arabia
1 linked record
Open supporting recordVerified chemistry for CAS 1313-27-5
Molybdenum trioxide
- IUPAC name
- trioxomolybdenum
- Molecular formula
- MoO3
- Molecular weight
- 143.95 g/mol
- Exact mass
- 145.890147 Da
- Monoisotopic mass
- 145.890147 Da
- Topological polar surface area
- 51.2 Ų
- Molecular complexity
- 61.0
- Formal charge
- 0
- Hydrogen-bond donors
- 0
- Hydrogen-bond acceptors
- 3
- Rotatable bonds
- 0
- Heavy atoms
- 4
- Covalent units
- 1
Names and synonyms reported to PubChem
16 more reported names
External database identifiers
- ChEBI:CHEBI:30627
- EPA DTXSID:DTXSID7020899
- PubMed:33038468
- PubMed:30389395
- PubMed:9029048
Advanced structure statistics
- Defined atom stereocentres
- 0
- Undefined atom stereocentres
- 0
- Defined bond stereocentres
- 0
- Undefined bond stereocentres
- 0
- 3D conformers
- 0
Machine-readable structure identifiers
- SMILES
O=[Mo](=O)=O- InChI
InChI=1S/Mo.3O- InChIKey
JKQOBWVOAYFWKG-UHFFFAOYSA-N
Evidence from additional scientific databases
NIH PubChem PUG-View
Attributed physical-property, hazard, environmental and use annotations.
- Boiling Point: 2111 °F at 760 mmHg (Sublimes) (NTP, 1992) Source: CAMEO Chemicals
- Boiling Point: 1155 °C, SUBLIMES Source: Hazardous Substances Data Bank (HSDB)
- Boiling Point: 1155 °C @760 [mm Hg] Source: PAC Chemical Database, U.S. Department of Energy
- Color/Form: WHITE OR SLIGHTLY YELLOW TO SLIGHTLY BLUISH POWDER OR GRANULES Source: Hazardous Substances Data Bank (HSDB)
- Color/Form: COLORLESS OR WHITE YELLOW RHOMBIC CRYSTALS Source: Hazardous Substances Data Bank (HSDB)
- Color/Form: WHITE POWDER AT ROOM TEMP, YELLOW AT ELEVATED TEMP Source: Hazardous Substances Data Bank (HSDB)
- Density: 4.69 at 68 °F (USCG, 1999) - Denser than water; will sink Source: CAMEO Chemicals
- Density: 4.69 @ 26 °C/4 °C Source: Hazardous Substances Data Bank (HSDB)
- Density: 4.696 @25 °C Source: PAC Chemical Database, U.S. Department of Energy
- Melting Point: 1463 °F (NTP, 1992) Source: CAMEO Chemicals
- Melting Point: 795 °C Source: Hazardous Substances Data Bank (HSDB)
- Melting Point: 802 °C Source: PAC Chemical Database, U.S. Department of Energy
- Odor: None Source: Hazardous Substances Data Bank (HSDB)
- Physical Description: Molybdenum trioxide appears as colorless to white or yellow odorless solid. Sinks in water. (USCG, 1999) Source: CAMEO Chemicals
- Physical Description: Large Crystals; CBI; Dry Powder; Other Solid; Wet Solid; Liquid; Dry Powder; Other Solid; Dry Powder; Large Crystals Source: EPA Chemical Data Reporting (CDR)
- Physical Description: White or slightly yellow to slightly bluish solid; [Merck Index] Light green odorless powder; Partially soluble in water (1.07 g/L at 18 deg C); [MSDSonline] A soluble compound; [ACGIH] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Solubility: less than 1 mg/mL at 75 °F (NTP, 1992) Source: CAMEO Chemicals
- Solubility: After strong ignition it is very slightly sol in acids Source: Hazardous Substances Data Bank (HSDB)
- Solubility: 0.490 g/1000 cc water @ 28 °C Source: Hazardous Substances Data Bank (HSDB)
- Solubility: Sol in concentrated mineral acids Source: Hazardous Substances Data Bank (HSDB)
- Solubility: Sol in soln of alkali hydroxides and soln of potassium bitartrate Source: Hazardous Substances Data Bank (HSDB)
- Solubility: 1.066 g/l water @ 18 °C Source: Hazardous Substances Data Bank (HSDB)
- Solubility: 20.55 g/l water @ 70 °C Source: Hazardous Substances Data Bank (HSDB)
- IARC Carcinogenic Agent: Molybdenum trioxide Source: International Agency for Research on Cancer (IARC)
- IARC Carcinogenic Classes: Group 2B: Possibly carcinogenic to humans Source: International Agency for Research on Cancer (IARC)
- IARC Monographs: Volume 118: (2018) Welding, Molybdenum Trioxide, and Indium Tin Oxide Source: International Agency for Research on Cancer (IARC)
- Publication Year: 2018 online Source: International Agency for Research on Cancer (IARC)
- Evaluation Year: 2017 Source: International Agency for Research on Cancer (IARC)
- Substance: Molybdenum Trioxide Source: NTP Technical Reports
- NTP Technical Report: TR-462: Toxicology and Carcinogenesis Studies of Molybdenum Trioxide (CASRN 1313-27-5) in F344 Rats and B6C3F1 Mice (Inhalation Studies) (1997 ) Source: NTP Technical Reports
- Peer Review Date: 12/05/95 Source: NTP Technical Reports
- Conclusion for Male Rat: Equivocal Evidence Source: NTP Technical Reports
- Conclusion for Female Rat: No Evidence Source: NTP Technical Reports
- Conclusion for Male Mice: Some Evidence Source: NTP Technical Reports
- Conclusion for Female Mice: Some Evidence Source: NTP Technical Reports
- First Aid: EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.; SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.; INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) shou Source: CAMEO Chemicals
- Signal: Warning Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
- GHS Hazard Statements: H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]; H351: Suspected of causing cancer [Warning Carcinogenicity] Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
- Precautionary Statement Codes: P203, P261, P264+P265, P271, P280, P304+P340, P305+P351+P338, P318, P319, P337+P317, P403+P233, P405, and P501 (click each P-code to see the statement) Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
- Signal: Warning Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: H319 (> 99.9%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H335 (> 99.9%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]; H351 (99.8%): Suspected of causing cancer [Warning Carcinogenicity] Source: European Chemicals Agency (ECHA)
- Precautionary Statement Codes: P203, P261, P264+P265, P271, P280, P304+P340, P305+P351+P338, P318, P319, P337+P317, P403+P233, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: Aggregated GHS information provided per 1297 reports by companies from 31 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- Signal: Danger Source: NITE-CMC
- GHS Hazard Statements: H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]; H351: Suspected of causing cancer [Warning Carcinogenicity]; H361: Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]; H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]; H373: May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure] Source: NITE-CMC
- Precautionary Statement Codes: P203, P260, P261, P264, P264+P265, P270, P271, P280, P304+P340, P305+P351+P338, P318, P319, P337+P317, P403+P233, P405, and P501 (click each P-code to see the statement) Source: NITE-CMC
- GHS Hazard Statements: H301: Toxic if swallowed [Danger Acute toxicity, oral]; H351: Suspected of causing cancer [Warning Carcinogenicity]; H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure]; H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]; H373: May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure] Source: NITE-CMC
- Precautionary Statement Codes: P203, P260, P264, P270, P280, P301+P316, P308+P316, P318, P319, P321, P330, P405, and P501 (click each P-code to see the statement) Source: NITE-CMC
- Consumer Uses: Catalyst; Corrosion inhibitor; Not Known or Reasonably Ascertainable; Intermediate; Alloys; Lubricating agent; Other Source: EPA Chemical Data Reporting (CDR)
- Industry Uses: Other; Lubricating agent; Alloys; Flame retardant; Corrosion inhibitor; Not Known or Reasonably Ascertainable; Catalyst; Intermediate Source: EPA Chemical Data Reporting (CDR)
- Sources/Uses: Used primarily in steel production as a corrosion inhibitor (~80-90%),then catalyst for refineries (~10%), then super alloys (~5%); [IARC Monograph 118] Used as a polymerization catalyst of olefins, a reagent in chemical analysis, a corrosion inhibitor, a catalyst in the petroleum industry, and an agricultural chemical; Also used to make molybdenum metal and alloys as well as ceramics, enamels, and pigments; [HSDB] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Industrial Processes with risk of exposure: Metal Preparation and Pouring [Category: Foundry]; Petroleum Production and Refining [Category: Industry]; Painting (Pigments, Binders, and Biocides) [Category: Paint] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Activities with risk of exposure: Ceramics making [Category: Hobbies]; Enameling [Category: Hobbies] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Uses: Pure molybdenum trioxide is used in chemical and catalyst manufacture and the technical product is added to steel as an alloying agent. Source: Hazardous Substances Data Bank (HSDB)
- Uses: To catalyze the polymerization of olefins Source: Hazardous Substances Data Bank (HSDB)
- Uses: Reagent in chem analysis Source: Hazardous Substances Data Bank (HSDB)
- Uses: MANUFACTURE OF MOLYBDENUM METAL & ALLOYS; CORROSION INHIBITOR; CATALYST IN PETROLEUM INDUSTRY; COMPONENT OF CERAMICS, ENAMELS & PIGMENTS; INTERMEDIATE FOR OTHER MOLYBDENUM CMPD Source: Hazardous Substances Data Bank (HSDB)
- Uses: AGRICULTURAL CHEMICAL Source: Hazardous Substances Data Bank (HSDB)
Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record
Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.
Additional source coverage and match status
| Source | Result | Checked |
|---|---|---|
| NIH PubChem PUG-View | Exact match | 2026-08-31 |
A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
Official source and provenance
- Registered source
- India BIS IS 4707 cosmetic ingredient standards
- Source reference
- IS 4707 (Part 2):2025 Annex A, entry 1469
- Source record ID
annex-a:1469- Source version
- IS 4707 (Part 2):2025, fifth revision
- Source language
- English
- Translation status
- Original is English
- Effective date
- 2025-08-09
- Source updated
- 2025-08-09
- Snapshot checked
- 2026-08-31 15:30 UTC
- Validation method
- 206 text layers; Annex A 1-1614 and Annex B 1-313 with seven lettered source rows
- SHA-256
905dd0326361c53da8a354b948331946951ac3ae27d60d8e2474efb051239603
Registered dataset notes
- Dataset coverage
- Complete current Part 2:2025 Annex A prohibited and Annex B restricted rows; Parts 1, 3 and 4 remain linked official checks
- Authority note
- Indian Standards referenced by the cosmetics regulatory framework; use the controlled current editions
How this record fits the market dataset
Status distribution
Condition text is present on 1931 of 1931 current records. An empty condition field is interpreted according to the record type above; it is never converted into an unrestricted-use claim.
India market context
Complete current Part 2 dataset plus official workflow for Parts 1, 3 and 4
Coverage version: Cosmetics Rules 2020 plus current BIS IS 4707 parts (1:2020, 2:2025, 3:2025, 4:2022)
All 1,614 prohibited Annex A rows and 317 numbered/lettered restricted Annex B rows from IS 4707 Part 2:2025; official checks remain for colourants, preservatives and UV filters in Parts 1, 3 and 4.
Verification checklist
- Confirm product class and current Cosmetics Rules/gazette amendments.
- Check all applicable parts of IS 4707 by exact identity.
- Apply Schedule S/other finished-product standards where relevant.
- Verify licence/import registration, labelling and testing requirements.
Official market sources
- India Cosmetics Rules 2020Official CDSCO rules and gazette updates; standards may require separate licensed sources
- India BIS IS 4707 cosmetic ingredient standardsIndian Standards referenced by the cosmetics regulatory framework; use the controlled current editions
Verification workflow and record completeness
Before using this result in a compliance decision
- Confirm that “Molybdenum trioxide (CAS No. 1313-27-5)” and every CAS/EC identifier refer to the material in your supplier specification.
- Confirm product class and current Cosmetics Rules/gazette amendments.
- Check all applicable parts of IS 4707 by exact identity.
- Apply Schedule S/other finished-product standards where relevant.
- Verify licence/import registration, labelling and testing requirements.
- Document the source version and recheck the regulator before manufacture, notification or market placement.
Fields available in this record
- Official substance nameAvailable
- CASAvailable
- ECNot supplied
- Separate condition textAvailable
- Effective dateAvailable
- Snapshot hash and methodAvailable
Questions this page answers
Stable citation
Molybdenum trioxide (CAS No. 1313-27-5). IS 4707 (Part 2):2025 Annex A, entry 1469. India. Source version IS 4707 (Part 2):2025, fifth revision. CosIng Checker regulatory record: https://cosingchecker.com/regulations/in/records/16063/
Cite the regulator as the legal authority. This page is a structured evidence index and verification aid, not a substitute for the official text or professional legal assessment.
Interpretation and limits for India
This official record identifies the substance as prohibited for cosmetic use in the stated market scope.
Do not rely on a formulation containing this identity until the cited source, effective date and exact substance match have been verified.
How to interpret the legal role
The cited row forms part of a binding rule or legally incorporated list for this market.
Evidence on this page
- Recorded outcome: Prohibited
- Legal role: Binding rule
- Source version: IS 4707 (Part 2):2025, fifth revision
- Effective date: 2025-08-09
What it does not prove
The standards are separate controlled publications; absence from a locally indexed excerpt is not permission.
Further authoritative substance research
These sources can add identity, safety, exposure or hazard context. A link is not evidence that the database contains this exact substance, and none of these sources overrides the market decision above.
Cosmetic Ingredient Review safety assessments
Expert Panel conclusions, assessed ingredient groups, use conditions, dates and report documents
Independent expert review considered by FDA; not a government approval or binding market rule
Research this identity at the sourceFDA Global Substance Registration System
UNII identifiers, preferred names, substance types, codes and public substance relationships
Identity registry only; UNII availability does not imply FDA review or approval
Research this identity at the sourceILO/WHO International Chemical Safety Cards
Hazards, symptoms, first aid, storage, incompatibilities and physical properties for covered chemicals
International occupational chemical-safety reference; not cosmetic-use approval
Research this identity at the sourceJapan NITE-CHRIP
Chemical identity, Japanese and foreign legal lists, GHS hazards and exposure-related information
Chemical-management evidence; cosmetic status remains governed by the applicable MHLW standard and market rules
Research this identity at the sourceNIOSH Pocket Guide to Chemical Hazards
REL, PEL, IDLH, properties, exposure routes, symptoms, target organs, first aid and measurement methods for covered workplace chemicals
US occupational-health guidance and limits; not a cosmetic ingredient decision
Research this identity at the sourceOECD eChemPortal
Gateway to authority-owned physical-property, fate, ecotoxicity, toxicity, exposure and GHS records
Discovery gateway; each linked authority remains responsible for its data
Research this identity at the sourceUS EPA CompTox CTX APIs
API key required for importDTXSID identity, experimental and predicted properties, toxicity, bioactivity, exposure and environmental data
Scientific and computational evidence; predictions must remain labelled and do not determine cosmetic legality
Research this identity at the source