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ProhibitedBinding ruleINOriginal is EnglishOfficial-source import checked

IS 4707. (CAS No. 7440-67-7). Acetonitrile (CAS No. 75-05-8)

IS 4707 Part 2:2025 Annex A lists this ingredient as one that must not form part of a cosmetic product in India.

All India recordsOpen ingredient profileCompare all marketsOpen official source

Regulatory decision and full conditions

Status
Prohibited
Legal role
Binding rule
Regulatory summary
IS 4707 Part 2:2025 Annex A lists this ingredient as one that must not form part of a cosmetic product in India.
Conditions and restrictions
Must not form part of the composition of cosmetic products. Apply the general trace and safety notes published after Annex A.

Substance identity

Official source name
IS 4707. (CAS No. 7440-67-7). Acetonitrile (CAS No. 75-05-8)
CAS
7440-67-7; 75-05-8
EC
231-176-9
Identity mapping
cas_number
Linked ingredient
ZIRCONIUM POWDER
Search this identity across the siteCAS 7440-67-7CAS 75-05-8EC 231-176-9

Linked CosIng identity data

Names and aliases

ZIRCONIUM POWDER

CosIng description: Zirconium Powder is a powdered metallic element

EU inventory restriction note: II/391

Recorded cosmetic function: ANTIPERSPIRANT

Function pages:ANTIPERSPIRANT

View the complete ingredient profile

Cross-market snapshot for this identity

Exact linked records currently present in this site. An absent market means no imported exact match, not permission to use the substance.

10 market datasets
PubChem 2D chemical structure for CAS 7440-67-7
CAS 7440-67-7PubChem CID 23995

Verified chemistry for CAS 7440-67-7

Zirconium

Zirconium atom is a titanium group element atom. — ChEBI

IUPAC name
zirconium
Molecular formula
Zr
Molecular weight
91.22 g/mol
Exact mass
89.904699 Da
Monoisotopic mass
89.904699 Da
Topological polar surface area
0.0 Ų
Molecular complexity
0.0
Formal charge
0
Hydrogen-bond donors
0
Hydrogen-bond acceptors
0
Rotatable bonds
0
Heavy atoms
1
Covalent units
1

Names and synonyms reported to PubChem

ZircatZrC6V6S92N3CZirconium MetallicumRefChem:57358231-176-9Zirconium powderzirconium atom
16 more reported names
Zirconium, elementalZirconium scrapHSDB 2528EINECS 231-176-9UNII-C6V6S92N3CUN1358UN1932UN2008UN2009UN2858Zirconium powder, dryZirconium foilZirconium rodCHEBI:33342EC 231-176-9Zirconium metal, dry, chemically produced, finer than 20 mesh particle size (UN2008)
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D conformers
0
Machine-readable structure identifiers
SMILES
[Zr]
InChI
InChI=1S/Zr
InChIKey
QCWXUUIWCKQGHC-UHFFFAOYSA-N

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 75-05-8
CAS 75-05-8PubChem CID 6342

Verified chemistry for CAS 75-05-8

Acetonitrile

Acetonitrile is a nitrile that is hydrogen cyanide in which the hydrogen has been replaced by a methyl group. It has a role as a polar aprotic solvent and an EC 3.5.1.4 (amidase) inhibitor. It is a volatile organic compound and an aliphatic nitrile. — ChEBI

IUPAC name
acetonitrile
Molecular formula
C2H3N
Molecular weight
41.05 g/mol
Exact mass
41.026549100 Da
Monoisotopic mass
41.026549100 Da
XLogP3
0.0
Topological polar surface area
23.8 Ų
Molecular complexity
29.0
Formal charge
0
Hydrogen-bond donors
0
Hydrogen-bond acceptors
1
Rotatable bonds
0
Heavy atoms
3
Covalent units
1

Names and synonyms reported to PubChem

Methyl cyanideCyanomethaneEthanenitrileEthyl nitrileMethane, cyano-MethanecarbonitrileAcetonitrilCyanure de methyl
16 more reported names
MethylkyanidUSAF EK-488MeCNRCRA waste number U003NCI-C60822AI3-00327Z072SB282NNSC-7593DTXCID909CHEBI:38472RefChem:6609200-835-2Methylkyanid [Czech]Cyanure de methyl [French]Acetonitril [German, Dutch]Acetonitrile, anhydrous
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D pharmacophore features
1
3D rings
0
3D hydrophobes
0
3D acceptor features
1
3D donor features
0
3D anionic centres
0
3D cationic centres
0
3D conformers
1
Effective 3D rotors
0.0
Machine-readable structure identifiers
SMILES
CC#N
InChI
InChI=1S/C2H3N/c1-2-3/h1H3
InChIKey
WEVYAHXRMPXWCK-UHFFFAOYSA-N

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Official source and provenance

Registered source
India BIS IS 4707 cosmetic ingredient standards
Source reference
IS 4707 (Part 2):2025 Annex A, entry 388
Source record ID
annex-a:388
Source version
IS 4707 (Part 2):2025, fifth revision
Source language
English
Translation status
Original is English
Effective date
2025-08-09
Source updated
2025-08-09
Snapshot checked
2026-08-31 15:30 UTC
Validation method
206 text layers; Annex A 1-1614 and Annex B 1-313 with seven lettered source rows
SHA-256
905dd0326361c53da8a354b948331946951ac3ae27d60d8e2474efb051239603

Registered dataset notes

Dataset coverage
Complete current Part 2:2025 Annex A prohibited and Annex B restricted rows; Parts 1, 3 and 4 remain linked official checks
Authority note
Indian Standards referenced by the cosmetics regulatory framework; use the controlled current editions
Inspect the exact official sourceRegulator guidance

How this record fits the market dataset

1931
current India records
1614
records marked Prohibited
1931
records from this source version
1836
market records with CAS identity

Status distribution

Prohibited: 1614Restricted: 317

Condition text is present on 1931 of 1931 current records. An empty condition field is interpreted according to the record type above; it is never converted into an unrestricted-use claim.

India market context

Complete current Part 2 dataset plus official workflow for Parts 1, 3 and 4

Coverage version: Cosmetics Rules 2020 plus current BIS IS 4707 parts (1:2020, 2:2025, 3:2025, 4:2022)

All 1,614 prohibited Annex A rows and 317 numbered/lettered restricted Annex B rows from IS 4707 Part 2:2025; official checks remain for colourants, preservatives and UV filters in Parts 1, 3 and 4.

Verification checklist

  1. Confirm product class and current Cosmetics Rules/gazette amendments.
  2. Check all applicable parts of IS 4707 by exact identity.
  3. Apply Schedule S/other finished-product standards where relevant.
  4. Verify licence/import registration, labelling and testing requirements.

Official market sources

Verification workflow and record completeness

Before using this result in a compliance decision

  1. Confirm that “IS 4707. (CAS No. 7440-67-7). Acetonitrile (CAS No. 75-05-8)” and every CAS/EC identifier refer to the material in your supplier specification.
  2. Confirm product class and current Cosmetics Rules/gazette amendments.
  3. Check all applicable parts of IS 4707 by exact identity.
  4. Apply Schedule S/other finished-product standards where relevant.
  5. Verify licence/import registration, labelling and testing requirements.
  6. Document the source version and recheck the regulator before manufacture, notification or market placement.

Fields available in this record

  • Official substance nameAvailable
  • CASAvailable
  • ECAvailable
  • Separate condition textAvailable
  • Effective dateAvailable
  • Snapshot hash and methodAvailable

Questions this page answers

This official record identifies the substance as prohibited for cosmetic use in the stated market scope. Do not rely on a formulation containing this identity until the cited source, effective date and exact substance match have been verified.

A prohibition entry may contain no separate condition text because the regulatory outcome is the prohibition itself. The standards are separate controlled publications; absence from a locally indexed excerpt is not permission.

The record cites IS 4707 (Part 2):2025 Annex A, entry 388, source version IS 4707 (Part 2):2025, fifth revision. Open the official source.

No. CAS helps resolve identity, but jurisdictions can classify the same substance differently and can apply different product scopes, limits, warnings and transition dates.

Stable citation

IS 4707. (CAS No. 7440-67-7). Acetonitrile (CAS No. 75-05-8). IS 4707 (Part 2):2025 Annex A, entry 388. India. Source version IS 4707 (Part 2):2025, fifth revision. CosIng Checker regulatory record: https://cosingchecker.com/regulations/in/records/14982/

Cite the regulator as the legal authority. This page is a structured evidence index and verification aid, not a substitute for the official text or professional legal assessment.

Interpretation and limits for India

This official record identifies the substance as prohibited for cosmetic use in the stated market scope.

Do not rely on a formulation containing this identity until the cited source, effective date and exact substance match have been verified.

How to interpret the legal role

The cited row forms part of a binding rule or legally incorporated list for this market.

Evidence on this page

  • Recorded outcome: Prohibited
  • Legal role: Binding rule
  • Source version: IS 4707 (Part 2):2025, fifth revision
  • Effective date: 2025-08-09

What it does not prove

The standards are separate controlled publications; absence from a locally indexed excerpt is not permission.

Further authoritative substance research

These sources can add identity, safety, exposure or hazard context. A link is not evidence that the database contains this exact substance, and none of these sources overrides the market decision above.

Cosmetic Ingredient Review safety assessments

Expert Panel conclusions, assessed ingredient groups, use conditions, dates and report documents

Independent expert review considered by FDA; not a government approval or binding market rule

Research this identity at the source

FDA Global Substance Registration System

UNII identifiers, preferred names, substance types, codes and public substance relationships

Identity registry only; UNII availability does not imply FDA review or approval

Research this identity at the source

ILO/WHO International Chemical Safety Cards

Hazards, symptoms, first aid, storage, incompatibilities and physical properties for covered chemicals

International occupational chemical-safety reference; not cosmetic-use approval

Research this identity at the source

Japan NITE-CHRIP

Chemical identity, Japanese and foreign legal lists, GHS hazards and exposure-related information

Chemical-management evidence; cosmetic status remains governed by the applicable MHLW standard and market rules

Research this identity at the source

NIOSH Pocket Guide to Chemical Hazards

REL, PEL, IDLH, properties, exposure routes, symptoms, target organs, first aid and measurement methods for covered workplace chemicals

US occupational-health guidance and limits; not a cosmetic ingredient decision

Research this identity at the source

OECD eChemPortal

Gateway to authority-owned physical-property, fate, ecotoxicity, toxicity, exposure and GHS records

Discovery gateway; each linked authority remains responsible for its data

Research this identity at the source

US EPA CompTox CTX APIs

API key required for import

DTXSID identity, experimental and predicted properties, toxicity, bioactivity, exposure and environmental data

Scientific and computational evidence; predictions must remain labelled and do not determine cosmetic legality

Research this identity at the source