Permitted list with conditionsBinding ruleGBOriginal is EnglishOfficial-source import checked

Bromochlorophene

The consolidated GB Cosmetics Regulation lists this record in Annex V.

Regulatory decision and full conditions

Status
Permitted list with conditions
Legal role
Binding rule
Regulatory summary
The consolidated GB Cosmetics Regulation lists this record in Annex V.
Conditions and restrictions
0,1%

Substance identity

Official source name
Bromochlorophene
CAS
15435-29-7
EC
239-446-8
Identity mapping
cas_number
Linked ingredient
BROMOCHLOROPHENE

Linked CosIng identity data

Names and aliases

BROMOCHLOROPHENE

CosIng description: 2,2'-Methylenebis(6-bromo-4-chlorophenol)

EU inventory restriction note: V/37

Recorded cosmetic function: ANTIMICROBIAL, DEODORANT, PRESERVATIVE

Function pages:ANTIMICROBIAL, DEODORANT, PRESERVATIVE

View the complete ingredient profile

Cross-market snapshot for this identity

Exact linked records currently present in this site. An absent market means no imported exact match, not permission to use the substance.

5 market datasets

European Union

Positive-list entry with conditions

1 linked record · 1 with specific conditions

Open supporting record

Great Britain

Current record
Permitted list with conditions

1 linked record · 1 with specific conditions

Open supporting record
PubChem 2D chemical structure for CAS 15435-29-7
CAS 15435-29-7PubChem CID 84907

Verified chemistry for CAS 15435-29-7

2,2'-Methylenebis(6-bromo-4-chlorophenol)

IUPAC name
2-bromo-6-[(3-bromo-5-chloro-2-hydroxyphenyl)methyl]-4-chlorophenol
Molecular formula
C13H8Br2Cl2O2
Molecular weight
426.9 g/mol
Exact mass
425.82476 Da
Monoisotopic mass
423.82681 Da
XLogP3
5.8
Topological polar surface area
40.5 Ų
Molecular complexity
280.0
Formal charge
0
Hydrogen-bond donors
2
Hydrogen-bond acceptors
2
Rotatable bonds
2
Heavy atoms
19
Covalent units
1

Names and synonyms reported to PubChem

BromochlorophenBromochloropheneBromchloropheneBrophenBromochlorofen2JZV1D2GW76,6'-Dibrom-4,4'-dichlor-2,2'-methylendiphenol3,3-Dibromo-5,5-dichloro-2,2-dihydroxydiphenylmethane
16 more reported names
RefChem:121562239-446-86,6'-METHYLENEBIS(2-BROMO-4-CHLOROPHENOL)3,3-Dibromo-5,5-dichloro-2,2-dihydroxy-diphenylmethane3,3'-Dibromo-5,5'-dichloro-2,2'-dihydroxydiphenylmethanePhenol, 2,2'-methylenebis(6-bromo-4-chloro-3,3'-Dwubromo-5,5'-dwuchloro-2,2'-dwuhydroksy-dwufenylo-metanPhenol, 2,2'-methylenebis[6-bromo-4-chloro-Bromochlorofen [Polish]C13H8Br2Cl2O2EINECS 239-446-8UNII-2JZV1D2GW7BRN 22939812-BROMO-6-((3-BROMO-5-CHLORO-2-HYDROXYPHENYL)METHYL)-4-CHLOROPHENOLBROMCHLOROPHENBis(3-bromo-5-chloro-2-hydroxyphenyl)methane
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D pharmacophore features
6
3D rings
2
3D hydrophobes
2
3D acceptor features
0
3D donor features
2
3D anionic centres
0
3D cationic centres
0
3D conformers
10
Effective 3D rotors
2.0
Machine-readable structure identifiers
SMILES
C1=C(C=C(C(=C1CC2=C(C(=CC(=C2)Cl)Br)O)O)Br)Cl
InChI
InChI=1S/C13H8Br2Cl2O2/c14-10-4-8(16)2-6(12(10)18)1-7-3-9(17)5-11(15)13(7)19/h2-5,18-19H,1H2
InChIKey
TYBHZVUFOINFDV-UHFFFAOYSA-N

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Official source and provenance

Registered source
Great Britain Cosmetics Regulation — consolidated Annexes II–VI and amendments
Source reference
GB Cosmetics Regulation, Annex V, entry 37
Source record ID
V-37
Source version
2026-08-15
Source language
English
Translation status
Original is English
Effective date
2026-08-15
Source updated
2026-08-19
Snapshot checked
2026-08-30 04:51 UTC
Validation method
legislation.gov.uk XML table parse; {'II': 1758, 'III': 326, 'IV': 154, 'V': 57, 'VI': 34}
SHA-256
e3a386d950f54c6e7a7f9e784d1bd46e52de725137e89d5630709824475215d8

Registered dataset notes

Dataset coverage
Complete consolidated GB Annexes II–VI, with later amendments versioned separately
Authority note
Binding GB schedules and versioned amendments to retained Regulation 1223/2009; applies to England, Wales and Scotland, not Northern Ireland
Source licence
Open Government Licence v3.0 / Crown copyright
Attribution
Contains public sector information licensed under the Open Government Licence v3.0.

How this record fits the market dataset

2329
current Great Britain records
245
records marked Permitted list with conditions
2329
records from this source version
2015
market records with CAS identity

Status distribution

Condition text is present on 517 of 2329 current records. An empty condition field is interpreted according to the record type above; it is never converted into an unrestricted-use claim.

Great Britain market context

Complete consolidated annex dataset

Coverage version: GB retained Regulation 1223/2009 schedules, effective 15 August 2026

Current consolidated Annexes II–VI for England, Scotland and Wales.

Verification checklist

  1. Confirm INCI/CAS/EC identity.
  2. Review every current GB Annex II–VI match.
  3. Check commencement dates and later statutory instruments.
  4. Verify SCPN, responsible-person, safety-report and labelling duties.

Official market sources

Verification workflow and record completeness

Before using this result in a compliance decision

  1. Confirm that “Bromochlorophene” and every CAS/EC identifier refer to the material in your supplier specification.
  2. Confirm INCI/CAS/EC identity.
  3. Review every current GB Annex II–VI match.
  4. Check commencement dates and later statutory instruments.
  5. Verify SCPN, responsible-person, safety-report and labelling duties.
  6. Document the source version and recheck the regulator before manufacture, notification or market placement.

Fields available in this record

  • Official substance nameAvailable
  • CASAvailable
  • ECAvailable
  • Separate condition textAvailable
  • Effective dateAvailable
  • Snapshot hash and methodAvailable

Questions this page answers

This identity appears on a market positive list for the list function represented by the source record. Confirm that the intended function and product use fall within the list scope and every stated condition.

Positive-list presence is purpose-specific and is not blanket approval for every cosmetic use. No annex match is not approval and does not cover Northern Ireland, which follows the applicable EU framework.

The record cites GB Cosmetics Regulation, Annex V, entry 37, source version 2026-08-15. Open the official source.

No. CAS helps resolve identity, but jurisdictions can classify the same substance differently and can apply different product scopes, limits, warnings and transition dates.

Stable citation

Bromochlorophene. GB Cosmetics Regulation, Annex V, entry 37. Great Britain. Source version 2026-08-15. CosIng Checker regulatory record: https://cosingchecker.com/regulations/gb/records/6631/

Cite the regulator as the legal authority. This page is a structured evidence index and verification aid, not a substitute for the official text or professional legal assessment.

Interpretation and limits for Great Britain

This identity appears on a market positive list for the list function represented by the source record.

Confirm that the intended function and product use fall within the list scope and every stated condition.

How to interpret the legal role

The cited row forms part of a binding rule or legally incorporated list for this market.

Evidence on this page

  • Recorded outcome: Permitted list with conditions
  • Legal role: Binding rule
  • Source version: 2026-08-15
  • Effective date: 2026-08-15

What it does not prove

No annex match is not approval and does not cover Northern Ireland, which follows the applicable EU framework.

Further authoritative substance research

These sources can add identity, safety, exposure or hazard context. A link is not evidence that the database contains this exact substance, and none of these sources overrides the market decision above.

Cosmetic Ingredient Review safety assessments

Expert Panel conclusions, assessed ingredient groups, use conditions, dates and report documents

Independent expert review considered by FDA; not a government approval or binding market rule

Research this identity at the source

FDA Global Substance Registration System

UNII identifiers, preferred names, substance types, codes and public substance relationships

Identity registry only; UNII availability does not imply FDA review or approval

Research this identity at the source

ILO/WHO International Chemical Safety Cards

Hazards, symptoms, first aid, storage, incompatibilities and physical properties for covered chemicals

International occupational chemical-safety reference; not cosmetic-use approval

Research this identity at the source

Japan NITE-CHRIP

Chemical identity, Japanese and foreign legal lists, GHS hazards and exposure-related information

Chemical-management evidence; cosmetic status remains governed by the applicable MHLW standard and market rules

Research this identity at the source

NIOSH Pocket Guide to Chemical Hazards

REL, PEL, IDLH, properties, exposure routes, symptoms, target organs, first aid and measurement methods for covered workplace chemicals

US occupational-health guidance and limits; not a cosmetic ingredient decision

Research this identity at the source

OECD eChemPortal

Gateway to authority-owned physical-property, fate, ecotoxicity, toxicity, exposure and GHS records

Discovery gateway; each linked authority remains responsible for its data

Research this identity at the source

US EPA CompTox CTX APIs

API key required for import

DTXSID identity, experimental and predicted properties, toxicity, bioactivity, exposure and environmental data

Scientific and computational evidence; predictions must remain labelled and do not determine cosmetic legality

Research this identity at the source