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ProhibitedOfficial guidanceCAOriginal is EnglishOfficial-source import checked

Nitrocresols and their alkali metal salts

Canada Hotlist: Nitrocresols and their alkali metal salts

Health Canada lists this ingredient as prohibited for use in cosmetic products.

All Canada recordsOpen ingredient profileCompare all marketsOpen official source

Regulatory decision and full conditions

Status
Prohibited
Legal role
Official guidance
Regulatory summary
Health Canada lists this ingredient as prohibited for use in cosmetic products.
Conditions and restrictions
Synonyms or related compounds: 2-Nitro-4-cresol; 2-Nitro-m-cresol; 3-Nitro-p-cresol; 4-Nitro-m-cresol; 4-Nitro-o-cresol; 5-Nitro-o-cresol; 6-Nitro-m-cresol; Sodium 4-nitro-m-cresolate

Substance identity

Official source name
Nitrocresols and their alkali metal salts
CAS
12167-20-3; 119-33-5; 4920-77-8; 2042-14-0; 2581-34-2; 5428-54-6; 700-38-9; 2666-76-4
EC
218-044-6
Identity mapping
cas_number
Linked ingredient
3-NITRO-P-CRESOL
Search this identity across the siteCAS 12167-20-3CAS 119-33-5CAS 4920-77-8CAS 2042-14-0CAS 2581-34-2CAS 5428-54-6CAS 700-38-9CAS 2666-76-4EC 218-044-6

Linked CosIng identity data

Names and aliases

3-NITRO-P-CRESOL

EU inventory restriction note: II/250

Recorded cosmetic function: HAIR DYEING

Function pages:HAIR DYEING

View the complete ingredient profile

Cross-market snapshot for this identity

Exact linked records currently present in this site. An absent market means no imported exact match, not permission to use the substance.

10 market datasets
PubChem 2D chemical structure for CAS 119-33-5
CAS 119-33-5PubChem CID 8391

Verified chemistry for CAS 119-33-5

4-Methyl-2-nitrophenol

IUPAC name
4-methyl-2-nitrophenol
Molecular formula
C7H7NO3
Molecular weight
153.14 g/mol
Exact mass
153.042593085 Da
Monoisotopic mass
153.042593085 Da
XLogP3
2.4
Topological polar surface area
66.1 Ų
Molecular complexity
154.0
Formal charge
0
Hydrogen-bond donors
1
Hydrogen-bond acceptors
3
Rotatable bonds
0
Heavy atoms
11
Covalent units
1

Names and synonyms reported to PubChem

2-NITRO-P-CRESOLPhenol, 4-methyl-2-nitro-2-Nitro-4-methylphenol4-Hydroxy-3-nitrotolueneo-Nitro-p-cresol2-Nitro-4-cresolp-Cresol, 2-nitro-P92KPK2NL3
16 more reported names
NSC-5387RefChem:477155204-315-64-METHYL-2-NITRO-PHENOLPhenol, methylnitro-WLN: WNR BQ E1NSC 5387EINECS 204-315-6UNII-P92KPK2NL3BRN 1868022AI3-15389Methylnitrophenol2-nitro p-cresol3(OR 4)-METHYL-2-NITROPHENOL4-methyl-2-nitro phenol4-06-00-02149 (Beilstein Handbook Reference)
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D pharmacophore features
5
3D rings
1
3D hydrophobes
0
3D acceptor features
2
3D donor features
1
3D anionic centres
1
3D cationic centres
0
3D conformers
1
Effective 3D rotors
1.0
Machine-readable structure identifiers
SMILES
CC1=CC(=C(C=C1)O)[N+](=O)[O-]
InChI
InChI=1S/C7H7NO3/c1-5-2-3-7(9)6(4-5)8(10)11/h2-4,9H,1H3
InChIKey
SYDNSSSQVSOXTN-UHFFFAOYSA-N

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match8391

Attributed physical-property, hazard, environmental and use annotations.

  • Signal: Warning Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]; H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H335 (98.1%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 53 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 12167-20-3
CAS 12167-20-3PubChem CID 8391

Verified chemistry for CAS 12167-20-3

4-Methyl-2-nitrophenol

IUPAC name
4-methyl-2-nitrophenol
Molecular formula
C7H7NO3
Molecular weight
153.14 g/mol
Exact mass
153.042593085 Da
Monoisotopic mass
153.042593085 Da
XLogP3
2.4
Topological polar surface area
66.1 Ų
Molecular complexity
154.0
Formal charge
0
Hydrogen-bond donors
1
Hydrogen-bond acceptors
3
Rotatable bonds
0
Heavy atoms
11
Covalent units
1

Names and synonyms reported to PubChem

119-33-52-NITRO-P-CRESOLPhenol, 4-methyl-2-nitro-2-Nitro-4-methylphenol4-Hydroxy-3-nitrotolueneo-Nitro-p-cresol2-Nitro-4-cresolp-Cresol, 2-nitro-
16 more reported names
P92KPK2NL3NSC-5387RefChem:477155204-315-64-METHYL-2-NITRO-PHENOLPhenol, methylnitro-WLN: WNR BQ E1NSC 5387EINECS 204-315-6UNII-P92KPK2NL3BRN 1868022AI3-15389Methylnitrophenol2-nitro p-cresol3(OR 4)-METHYL-2-NITROPHENOL4-methyl-2-nitro phenol
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D pharmacophore features
5
3D rings
1
3D hydrophobes
0
3D acceptor features
2
3D donor features
1
3D anionic centres
1
3D cationic centres
0
3D conformers
1
Effective 3D rotors
1.0
Machine-readable structure identifiers
SMILES
CC1=CC(=C(C=C1)O)[N+](=O)[O-]
InChI
InChI=1S/C7H7NO3/c1-5-2-3-7(9)6(4-5)8(10)11/h2-4,9H,1H3
InChIKey
SYDNSSSQVSOXTN-UHFFFAOYSA-N

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match8391

Attributed physical-property, hazard, environmental and use annotations.

  • Signal: Warning Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]; H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H335 (98.1%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 53 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 2042-14-0
CAS 2042-14-0PubChem CID 16271

Verified chemistry for CAS 2042-14-0

3-Nitro-p-cresol

IUPAC name
4-methyl-3-nitrophenol
Molecular formula
C7H7NO3
Molecular weight
153.14 g/mol
Exact mass
153.042593085 Da
Monoisotopic mass
153.042593085 Da
XLogP3
2.1
Topological polar surface area
66.1 Ų
Molecular complexity
154.0
Formal charge
0
Hydrogen-bond donors
1
Hydrogen-bond acceptors
3
Rotatable bonds
0
Heavy atoms
11
Covalent units
1

Names and synonyms reported to PubChem

4B422HUD6HEINECS 218-044-6NSC-41205NSC 412054Methyl3nitrophenolRefChem:5044613-NITRO-P-CRESOL [INCI]218-044-6
16 more reported names
3-Nitro-4-methylphenol4-methyl-3-nitro-phenol4-Hydroxy-2-nitrotoluenePhenol, 4-methyl-3-nitro-2-Nitro-4-hydroxytoluenep-Cresol, 3-nitro-4-methyl-5-nitrophenolUNII-4B422HUD6H4-Methyl-5-nitrophenol; 4-Hydroxy-2-nitrotoluene; 3-Nitro-p-cresol;3-Nitro-p-kresol2(OR 4)-METHYL-3-NITROPHENOL2-nitro-4-hydroxy toluene4-Hydroxy-1-methyl-2-nitrobenzeneCS-D1224TN9339MSK8742-1000M
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D pharmacophore features
5
3D rings
1
3D hydrophobes
0
3D acceptor features
2
3D donor features
1
3D anionic centres
1
3D cationic centres
0
3D conformers
1
Effective 3D rotors
1.0
Machine-readable structure identifiers
SMILES
CC1=C(C=C(C=C1)O)[N+](=O)[O-]
InChI
InChI=1S/C7H7NO3/c1-5-2-3-6(9)4-7(5)8(10)11/h2-4,9H,1H3
InChIKey
BQEXDUKMTVYBRK-UHFFFAOYSA-N

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 2581-34-2
CAS 2581-34-2PubChem CID 17412

Verified chemistry for CAS 2581-34-2

3-Methyl-4-nitrophenol

IUPAC name
3-methyl-4-nitrophenol
Molecular formula
C7H7NO3
Molecular weight
153.14 g/mol
Exact mass
153.042593085 Da
Monoisotopic mass
153.042593085 Da
XLogP3
2.5
Topological polar surface area
66.1 Ų
Molecular complexity
154.0
Formal charge
0
Hydrogen-bond donors
1
Hydrogen-bond acceptors
3
Rotatable bonds
0
Heavy atoms
11
Covalent units
1

Names and synonyms reported to PubChem

4-Nitro-m-cresol4-Nitro-3-cresol5-Hydroxy-2-nitrotoluene4-Nitro-3-methylphenol2-Nitro-5-hydroxytoluenePhenol, 3-methyl-4-nitro-4-Nitro-5-methylphenolm-Cresol, 4-nitro-
16 more reported names
P-NITRO-M-CRESOL2CC94832EUNSC-69190CHEBI:38683RefChem:94775219-952-54-Nitro-1-hydroxy-3-methylbenzene5-Methyl-4-nitrophenol3-methyl-4-nitro-phenolNSC 69190p-Nitro-m-methylphenolp-?Nitro-?m-?cresolEINECS 219-952-54-NITRO-META-CRESOLBRN 1868105UNII-2CC94832EU
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D pharmacophore features
5
3D rings
1
3D hydrophobes
0
3D acceptor features
2
3D donor features
1
3D anionic centres
1
3D cationic centres
0
3D conformers
1
Effective 3D rotors
1.0
Machine-readable structure identifiers
SMILES
CC1=C(C=CC(=C1)O)[N+](=O)[O-]
InChI
InChI=1S/C7H7NO3/c1-5-4-6(9)2-3-7(5)8(10)11/h2-4,9H,1H3
InChIKey
PIIZYNQECPTVEO-UHFFFAOYSA-N

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 4920-77-8
CAS 4920-77-8PubChem CID 21026

Verified chemistry for CAS 4920-77-8

3-Methyl-2-nitrophenol

IUPAC name
3-methyl-2-nitrophenol
Molecular formula
C7H7NO3
Molecular weight
153.14 g/mol
Exact mass
153.042593085 Da
Monoisotopic mass
153.042593085 Da
XLogP3
2.3
Topological polar surface area
66.1 Ų
Molecular complexity
154.0
Formal charge
0
Hydrogen-bond donors
1
Hydrogen-bond acceptors
3
Rotatable bonds
0
Heavy atoms
11
Covalent units
1

Names and synonyms reported to PubChem

2-Nitro-m-cresolPhenol, 3-methyl-2-nitro-m-Cresol, 2-nitro-I4QBB2L3C0NSC-41206RefChem:94736225-546-92-Nitro-3-methylphenol
16 more reported names
3-methyl-2-nitro-phenol2-Nitro-3-hydroxytoluene3-Hydroxy-2-nitrotoluene2-Nitro-3-cresol2-HYDROXY-6-METHYLNITROBENZENE2-hydroxy-6-methyl-nitrobenzeneUNII-I4QBB2L3C0EINECS 225-546-9methyl-2-nitrophenolNSC 412063-Methyl-2-nitrophenol, 99%AC-3190CS-W006081PS-5340BP-12499N0552
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D pharmacophore features
5
3D rings
1
3D hydrophobes
0
3D acceptor features
2
3D donor features
1
3D anionic centres
1
3D cationic centres
0
3D conformers
1
Effective 3D rotors
1.0
Machine-readable structure identifiers
SMILES
CC1=C(C(=CC=C1)O)[N+](=O)[O-]
InChI
InChI=1S/C7H7NO3/c1-5-3-2-4-6(9)7(5)8(10)11/h2-4,9H,1H3
InChIKey
QIORDSKCCHRSSD-UHFFFAOYSA-N

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 5428-54-6
CAS 5428-54-6PubChem CID 93576

Verified chemistry for CAS 5428-54-6

2-Methyl-5-nitrophenol

IUPAC name
2-methyl-5-nitrophenol
Molecular formula
C7H7NO3
Molecular weight
153.14 g/mol
Exact mass
153.042593085 Da
Monoisotopic mass
153.042593085 Da
XLogP3
1.8
Topological polar surface area
66.1 Ų
Molecular complexity
154.0
Formal charge
0
Hydrogen-bond donors
1
Hydrogen-bond acceptors
3
Rotatable bonds
0
Heavy atoms
11
Covalent units
1

Names and synonyms reported to PubChem

Phenol, 2-methyl-5-nitro-NSC 41203EINECS 226-580-7NSC 12987NSC 50664RefChem:88183InChI=1/C7H7NO3/c1-5-2-3-6(8(10)11)4-7(5)9/h2-4,9H,1HUMFDLIXUUJMPSI-UHFFFAOYSA-N
16 more reported names
5-Nitro-o-cresol2-Hydroxy-4-nitrotoluene5-Nitro-2-cresolo-Cresol, 5-nitro-5-Nitro-2-methylphenol4XA3M9BL6BNSC-12987NSC-41203NSC-506642-Methyl-5-nitro-phenol2-Methy-5-nitrophenol2-methyl-5-nitro phenol5-Nitro-o-kresol2-Hydroxy-4-nitrotoluene;5-Nitro-2-cresol;5-Nitro-2-methylphenol;5-Nitro-o-cresol;5-Nitro-o-methylphenol;UNII-4XA3M9BL6B2-Methyl-5-nitrophenol, 98%
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D pharmacophore features
5
3D rings
1
3D hydrophobes
0
3D acceptor features
2
3D donor features
1
3D anionic centres
1
3D cationic centres
0
3D conformers
1
Effective 3D rotors
1.0
Machine-readable structure identifiers
SMILES
CC1=C(C=C(C=C1)[N+](=O)[O-])O
InChI
InChI=1S/C7H7NO3/c1-5-2-3-6(8(10)11)4-7(5)9/h2-4,9H,1H3
InChIKey
UMFDLIXUUJMPSI-UHFFFAOYSA-N

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 700-38-9
CAS 700-38-9PubChem CID 12788

Verified chemistry for CAS 700-38-9

6-Nitro-m-cresol

IUPAC name
5-methyl-2-nitrophenol
Molecular formula
C7H7NO3
Molecular weight
153.14 g/mol
Exact mass
153.042593085 Da
Monoisotopic mass
153.042593085 Da
XLogP3
2.3
Topological polar surface area
66.1 Ų
Molecular complexity
154.0
Formal charge
0
Hydrogen-bond donors
1
Hydrogen-bond acceptors
3
Rotatable bonds
0
Heavy atoms
11
Covalent units
1

Names and synonyms reported to PubChem

3-Hydroxy-4-nitrotoluene5-methyl-2-nitro-phenolm-Cresol, 6-nitro-2-nitro-5-methylphenolNSC 3142EINECS 211-843-0UNII-Z0B5EO9752AI3-19031
16 more reported names
Z0B5EO9752NSC-3142NITRO-M-CRESOL, 6-5-Methyl-2-nitrophenol (3-6)RefChem:105088211-843-0InChI=1/C7H7NO3/c1-5-2-3-6(8(10)11)7(9)4-5/h2-4,9H,1HNQXUSSVLFOBRSE-UHFFFAOYSA-NPhenol, 5-methyl-2-nitro-3-Methyl-6-nitrophenol6-Nitro-3-cresolNSC31425-Methyl-2-nitrophenol, 97%2-hydroxy-4-methyl-1-nitrobenzeneAC-2467CS-W005409
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D pharmacophore features
5
3D rings
1
3D hydrophobes
0
3D acceptor features
2
3D donor features
1
3D anionic centres
1
3D cationic centres
0
3D conformers
1
Effective 3D rotors
1.0
Machine-readable structure identifiers
SMILES
CC1=CC(=C(C=C1)[N+](=O)[O-])O
InChI
InChI=1S/C7H7NO3/c1-5-2-3-6(8(10)11)7(9)4-5/h2-4,9H,1H3
InChIKey
NQXUSSVLFOBRSE-UHFFFAOYSA-N

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Official source and provenance

Registered source
Health Canada Cosmetic Ingredient Hotlist
Source reference
Hotlist prohibited entry 340
Source record ID
prohibited:340
Source version
Health Canada Hotlist 2025-08-13
Source language
English
Translation status
Original is English
Source updated
2025-08-13
Snapshot checked
2026-08-30 04:07 UTC
Validation method
strict HTML tables t1=490 and t2=90
SHA-256
8b52ff573d08373ee90121f6a701b3607e4a3d6fc748a7d56171eb53510af91a

Registered dataset notes

Dataset coverage
Administrative prohibitions, restrictions, conditions and warning requirements
Authority note
Official Health Canada compliance indicator; not a complete safety clearance
Inspect the exact official sourceRegulator guidance

How this record fits the market dataset

580
current Canada records
490
records marked Prohibited
580
records from this source version
516
market records with CAS identity

Status distribution

Prohibited: 490Restricted: 90

Condition text is present on 172 of 580 current records. An empty condition field is interpreted according to the record type above; it is never converted into an unrestricted-use claim.

Canada market context

Complete Hotlist snapshot

Coverage version: Health Canada Cosmetic Ingredient Hotlist, 13 August 2025

All prohibited and restricted Hotlist entries, including conditions and warning requirements published in the official list.

Verification checklist

  1. Search English/French names and CAS identifiers.
  2. Apply every restriction, concentration and label warning.
  3. Check Food and Drugs Act/Cosmetic Regulations requirements.
  4. Recheck the current Hotlist before notification or sale.

Official market sources

Verification workflow and record completeness

Before using this result in a compliance decision

  1. Confirm that “Nitrocresols and their alkali metal salts” and every CAS/EC identifier refer to the material in your supplier specification.
  2. Search English/French names and CAS identifiers.
  3. Apply every restriction, concentration and label warning.
  4. Check Food and Drugs Act/Cosmetic Regulations requirements.
  5. Recheck the current Hotlist before notification or sale.
  6. Document the source version and recheck the regulator before manufacture, notification or market placement.

Fields available in this record

  • Official substance nameAvailable
  • CASAvailable
  • ECAvailable
  • Separate condition textAvailable
  • Effective dateNot supplied
  • Snapshot hash and methodAvailable

Questions this page answers

This official record identifies the substance as prohibited for cosmetic use in the stated market scope. Do not rely on a formulation containing this identity until the cited source, effective date and exact substance match have been verified.

A prohibition entry may contain no separate condition text because the regulatory outcome is the prohibition itself. The Hotlist is an administrative compliance tool, not an exhaustive safety approval list.

The record cites Hotlist prohibited entry 340, source version Health Canada Hotlist 2025-08-13. Open the official source.

No. CAS helps resolve identity, but jurisdictions can classify the same substance differently and can apply different product scopes, limits, warnings and transition dates.

Stable citation

Nitrocresols and their alkali metal salts. Hotlist prohibited entry 340. Canada. Source version Health Canada Hotlist 2025-08-13. CosIng Checker regulatory record: https://cosingchecker.com/regulations/ca/records/340/

Cite the regulator as the legal authority. This page is a structured evidence index and verification aid, not a substitute for the official text or professional legal assessment.

Interpretation and limits for Canada

This official record identifies the substance as prohibited for cosmetic use in the stated market scope.

Do not rely on a formulation containing this identity until the cited source, effective date and exact substance match have been verified.

How to interpret the legal role

The authority uses this source as compliance guidance; the underlying legislation remains controlling.

Evidence on this page

  • Recorded outcome: Prohibited
  • Legal role: Official guidance
  • Source version: Health Canada Hotlist 2025-08-13

What it does not prove

The Hotlist is an administrative compliance tool, not an exhaustive safety approval list.

Further authoritative substance research

These sources can add identity, safety, exposure or hazard context. A link is not evidence that the database contains this exact substance, and none of these sources overrides the market decision above.

Cosmetic Ingredient Review safety assessments

Expert Panel conclusions, assessed ingredient groups, use conditions, dates and report documents

Independent expert review considered by FDA; not a government approval or binding market rule

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FDA Global Substance Registration System

UNII identifiers, preferred names, substance types, codes and public substance relationships

Identity registry only; UNII availability does not imply FDA review or approval

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ILO/WHO International Chemical Safety Cards

Hazards, symptoms, first aid, storage, incompatibilities and physical properties for covered chemicals

International occupational chemical-safety reference; not cosmetic-use approval

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Japan NITE-CHRIP

Chemical identity, Japanese and foreign legal lists, GHS hazards and exposure-related information

Chemical-management evidence; cosmetic status remains governed by the applicable MHLW standard and market rules

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NIOSH Pocket Guide to Chemical Hazards

REL, PEL, IDLH, properties, exposure routes, symptoms, target organs, first aid and measurement methods for covered workplace chemicals

US occupational-health guidance and limits; not a cosmetic ingredient decision

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OECD eChemPortal

Gateway to authority-owned physical-property, fate, ecotoxicity, toxicity, exposure and GHS records

Discovery gateway; each linked authority remains responsible for its data

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US EPA CompTox CTX APIs

API key required for import

DTXSID identity, experimental and predicted properties, toxicity, bioactivity, exposure and environmental data

Scientific and computational evidence; predictions must remain labelled and do not determine cosmetic legality

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