Lithium hydroxide Lithium hydroxide CAS No 1310-65-2
ASEAN Annex III lists this record among substances allowed only under restrictions and conditions. Member-state transition rules and deviations still require local verification.
Regulatory decision and full conditions
- Status
- Restricted
- Legal role
- Binding rule
- Regulatory summary
- ASEAN Annex III lists this record among substances allowed only under restrictions and conditions. Member-state transition rules and deviations still require local verification.
- Conditions and restrictions
- (a) Hair straightener 1. General use 2. Professional use (b) pH adjuster – for depilatories (c) Other uses as pH adjuster (for rinse-off products only) · (a) 1. 2% by weight (6) 2. 4.5% by weight (6) · (b) pH < 12.7 (c) pH < 11 · (a) 1. • Contains alkali • Avoid contact with eyes • Can cause blindness • Keep out of reach of children 2. • For Professional use only • Avoid contact with eyes • Can cause blindness (b) • Contains alkali • Keep out of reach of children • Avoid contact with eyes
Substance identity
- Official source name
- Lithium hydroxide Lithium hydroxide CAS No 1310-65-2
- CAS
- 1310-65-2
- EC
- 215-183-4
- Identity mapping
- cas_number
- Linked ingredient
- LITHIUM HYDROXIDE
Linked CosIng identity data
Names and aliases
CosIng description: Lithium hydroxide
EU inventory restriction note: III/15b
Recorded cosmetic function: BUFFERING, HAIR WAVING OR STRAIGHTENING
Function pages:BUFFERING, HAIR WAVING OR STRAIGHTENING
View the complete ingredient profileCross-market snapshot for this identity
Exact linked records currently present in this site. An absent market means no imported exact match, not permission to use the substance.
European Union
1 linked record · 1 with specific conditions
Open supporting recordGreat Britain
1 linked record · 1 with specific conditions
Open supporting recordNew Zealand
1 linked record · 1 with specific conditions
Open supporting recordASEAN
Current record1 linked record · 1 with specific conditions
Open supporting recordSouth Korea
1 linked record · 1 with specific conditions
Open supporting recordIndia
1 linked record · 1 with specific conditions
Open supporting recordSaudi Arabia
1 linked record
Open supporting recordVerified chemistry for CAS 1310-65-2
Lithium Hydroxide
Lithium hydroxide is an alkali metal hydroxide. — ChEBI
- IUPAC name
- lithium hydroxide
- Molecular formula
- HLiO
- Molecular weight
- 24.0 g/mol
- Exact mass
- 24.01874309 Da
- Monoisotopic mass
- 24.01874309 Da
- Topological polar surface area
- 1.0 Ų
- Molecular complexity
- 2.0
- Formal charge
- 0
- Hydrogen-bond donors
- 1
- Hydrogen-bond acceptors
- 1
- Rotatable bonds
- 0
- Heavy atoms
- 2
- Covalent units
- 2
Names and synonyms reported to PubChem
16 more reported names
External database identifiers
- ChEBI:CHEBI:33979
- EPA DTXSID:DTXSID70893845
- EPA DTXSID:DTXSID901337186
Advanced structure statistics
- Defined atom stereocentres
- 0
- Undefined atom stereocentres
- 0
- Defined bond stereocentres
- 0
- Undefined bond stereocentres
- 0
- 3D conformers
- 0
Machine-readable structure identifiers
- SMILES
[Li+].[OH-]- InChI
InChI=1S/Li.H2O/h;1H2/q+1;/p-1- InChIKey
WMFOQBRAJBCJND-UHFFFAOYSA-M
Evidence from additional scientific databases
NIH PubChem PUG-View
Attributed physical-property, hazard, environmental and use annotations.
- Boiling Point: 1626 °C @760 [mm Hg] Source: PAC Chemical Database, U.S. Department of Energy
- Density: 2.54 g/cm³ Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Density: 1.45 @25 °C Source: PAC Chemical Database, U.S. Department of Energy
- Melting Point: 450-471 °C Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Melting Point: 473 °C Source: PAC Chemical Database, U.S. Department of Energy
- Physical Description: Lithium hydroxide, solution appears as a clear to water-white liquid which may have a pungent odor. Contact may cause severe irritation to skin, eyes, and mucous membranes. It may be toxic by ingestion, inhalation and skin absorption. It is used to make other chemicals. Source: CAMEO Chemicals
- Physical Description: Large Crystals; Liquid; Wet Solid; Dry Powder; Liquid Source: EPA Chemical Data Reporting (CDR)
- Physical Description: White crystals or granular powder; [AIHA] Readily absorbs carbon dioxide and water from air; [Merck Index] White odorless granules; Hygroscopic; [Alfa Aesar MSDS] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Physical Description: COLOURLESS-TO-WHITE HYGROSCOPIC CRYSTALS. Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Solubility: Solubility in water, g/100ml at 20 °C: 12.8 (good) Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Vapor Pressure: Vapor pressure, Pa at 20 °C: (negligible) Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Exposure Routes: The substance can be absorbed into the body by inhalation of its aerosol and by ingestion. Serious local effects by all routes of exposure. Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- First Aid: Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]:; Refer to the "General First Aid" section. Specific First Aid: For corrosives, in case of contact, immediately flush skin or eyes with running water for at least 30 minutes. Additional flushing may be required. (ERG, 2024) Source: CAMEO Chemicals
- ERG2024, Guide 154 (Lithium hydroxide, solution; Lithium hydroxide): General First Aid:; · Call 911 or emergency medical service.; · Ensure that medical personnel are aware of the material(s) involved, take precautions to protect themselves and avoid contamination.; · Move victim to fresh air if it can be done safely.; · Administer oxygen if breathing is difficult.; · If victim is not breathing:; -- DO NOT perform mouth-to-mouth resuscitation; the victim may have ingested or inhaled the substance.; -- If equipped and pulse detected, wash face and mouth, then give artificial respiration using a proper respiratory medical device (bag-valve mask, pocket mask equipped with a one-way valve or other device).; -- If no pulse detected or no respiratory medical device available, provide continuous compressions. Conduct a pulse check every two minutes or monitor for any signs of spontaneous respirations.; · Remove and isolate contaminated clothing and shoes.; · For minor skin contact, avoid spreading material on unaffected skin.; · In case of contact with substance, remove immediately by flushing skin or eyes with running water for at least 20 minutes.; · For severe burns, immediate medical attention is required.; · Effects of exposure (inhalation, ingestion, Source: Emergency Response Guidebook (ERG)
- ERG2024, Guide 154 (Lithium hydroxide; Lithium hydroxide, solution): General First Aid:; · Call 911 or emergency medical service.; · Ensure that medical personnel are aware of the material(s) involved, take precautions to protect themselves and avoid contamination.; · Move victim to fresh air if it can be done safely.; · Administer oxygen if breathing is difficult.; · If victim is not breathing:; -- DO NOT perform mouth-to-mouth resuscitation; the victim may have ingested or inhaled the substance.; -- If equipped and pulse detected, wash face and mouth, then give artificial respiration using a proper respiratory medical device (bag-valve mask, pocket mask equipped with a one-way valve or other device).; -- If no pulse detected or no respiratory medical device available, provide continuous compressions. Conduct a pulse check every two minutes or monitor for any signs of spontaneous respirations.; · Remove and isolate contaminated clothing and shoes.; · For minor skin contact, avoid spreading material on unaffected skin.; · In case of contact with substance, remove immediately by flushing skin or eyes with running water for at least 20 minutes.; · For severe burns, immediate medical attention is required.; · Effects of exposure (inhalation, ingestion, Source: Emergency Response Guidebook (ERG)
- Note: This chemical does not meet GHS hazard criteria for 9.7% (95 of 980) of reports. Source: European Chemicals Agency (ECHA)
- Signal: Danger Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: H301 (12.6%): Toxic if swallowed [Danger Acute toxicity, oral]; H302 (73.6%): Harmful if swallowed [Warning Acute toxicity, oral]; H311 (10.9%): Toxic in contact with skin [Danger Acute toxicity, dermal]; H314 (89.8%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]; H318 (72.4%): Causes serious eye damage [Danger Serious eye damage/eye irritation] Source: European Chemicals Agency (ECHA)
- Precautionary Statement Codes: P260, P262, P264, P264+P265, P270, P280, P301+P316, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P321, P330, P361+P364, P363, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: Aggregated GHS information provided per 980 reports by companies from 28 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Reported as not meeting GHS hazard criteria per 95 of 980 reports by companies.; There are 26 notifications provided by 885 of 980 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- Signal: Danger Source: NITE-CMC
- GHS Hazard Statements: H301: Toxic if swallowed [Danger Acute toxicity, oral]; H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]; H318: Causes serious eye damage [Danger Serious eye damage/eye irritation]; H331: Toxic if inhaled [Danger Acute toxicity, inhalation]; H336: May cause drowsiness or dizziness [Warning Specific target organ toxicity, single exposure; Narcotic effects]; H360: May damage fertility or the unborn child [Danger Reproductive toxicity]; H362: May cause harm to breast-fed children [Reproductive toxicity, effects on or via lactation]; H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure]; H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure] Source: NITE-CMC
- Precautionary Statement Codes: P203, P260, P261, P263, P264, P264+P265, P270, P271, P280, P301+P316, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P308+P316, P316, P317, P318, P319, P321, P330, P363, P403+P233, P405, and P501 (click each P-code to see the statement) Source: NITE-CMC
- GHS Hazard Statements: H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]; H318: Causes serious eye damage [Danger Serious eye damage/eye irritation]; H331: Toxic if inhaled [Danger Acute toxicity, inhalation]; H360: May damage fertility or the unborn child [Danger Reproductive toxicity]; H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure] Source: NITE-CMC
- Precautionary Statement Codes: P203, P260, P261, P264, P264+P265, P270, P271, P280, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P308+P316, P316, P317, P318, P321, P363, P403+P233, P405, and P501 (click each P-code to see the statement) Source: NITE-CMC
- Signal: Danger Source: Hazardous Chemical Information System (HCIS), Safe Work Australia
- GHS Hazard Statements: H302: Harmful if swallowed [Warning Acute toxicity, oral]; H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation] Source: Hazardous Chemical Information System (HCIS), Safe Work Australia
- Consumer Uses: Lubricating agent; Viscosity modifiers; Ion exchange agent Source: EPA Chemical Data Reporting (CDR)
- Industry Uses: Absorbent; Ion exchange agent; Viscosity modifiers; Intermediate; Dye; Lubricating agent; Processing aids not otherwise specified Source: EPA Chemical Data Reporting (CDR)
- Sources/Uses: Used in photographic developing solutions, alkaline storage batteries, lithium-based greases, polymerization catalysts, carbon dioxide absorbents, alkyd paints, textile dye solubilizers, and copper electroplating baths; Produced along with lithium oxide when lithium-aluminum alloys are heated by welding or cutting; [AIHA] Used in cosmetics; [ExPub: EC] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Industrial Processes with risk of exposure: Welding [Category: Weld]; Electroplating [Category: Plate]; Battery Manufacturing [Category: Industry]; Painting (Pigments, Binders, and Biocides) [Category: Paint]; Gas Welding and Cutting [Category: Weld]; Photographic Processing [Category: Other]; Textiles (Printing, Dyeing, or Finishing) [Category: Industry] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record
Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.
Additional source coverage and match status
| Source | Result | Checked |
|---|---|---|
| NIH PubChem PUG-View | Exact match | 2026-08-31 |
A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
Official source and provenance
- Registered source
- ASEAN Cosmetic Directive annexes
- Source reference
- ASEAN Annex III, reference 15b
- Source record ID
III-15b- Source version
- 2026-1
- Source language
- English
- Translation status
- Original is English
- Source updated
- 2026-06-22
- Snapshot checked
- 2026-08-30 04:44 UTC
- Validation method
- pdfplumber ruled-table extraction with per-annex reviewed counts
- SHA-256
ffad59f6c01a92c82042c54203ee14969425c2a82bd04c2f4012ff82513e69f1
Registered dataset notes
- Dataset coverage
- Banned, restricted and positive-list substances under the harmonised ASEAN framework
- Authority note
- Regional directive; member-state transitions and deviations still require local verification
How this record fits the market dataset
Status distribution
Condition text is present on 462 of 2224 current records. An empty condition field is interpreted according to the record type above; it is never converted into an unrestricted-use claim.
ASEAN market context
Complete regional annex dataset
Coverage version: ASEAN Cosmetic Directive annexes 2026-1, 22 June 2026
Annexes II, III, IV, VI and VII covering prohibited, restricted and positive-list substances.
Verification checklist
- Search all ACD annexes by name and identifiers.
- Apply product type, maximum level and warning conditions.
- Confirm the target member state's adoption and transition date.
- Complete the local notification and responsible-company requirements.
Official market sources
- ASEAN Cosmetic Directive annexesRegional directive; member-state transitions and deviations still require local verification
Verification workflow and record completeness
Before using this result in a compliance decision
- Confirm that “Lithium hydroxide Lithium hydroxide CAS No 1310-65-2” and every CAS/EC identifier refer to the material in your supplier specification.
- Search all ACD annexes by name and identifiers.
- Apply product type, maximum level and warning conditions.
- Confirm the target member state's adoption and transition date.
- Complete the local notification and responsible-company requirements.
- Document the source version and recheck the regulator before manufacture, notification or market placement.
Fields available in this record
- Official substance nameAvailable
- CASAvailable
- ECAvailable
- Separate condition textAvailable
- Effective dateNot supplied
- Snapshot hash and methodAvailable
Questions this page answers
Stable citation
Lithium hydroxide Lithium hydroxide CAS No 1310-65-2. ASEAN Annex III, reference 15b. ASEAN. Source version 2026-1. CosIng Checker regulatory record: https://cosingchecker.com/regulations/asean/records/3884/
Cite the regulator as the legal authority. This page is a structured evidence index and verification aid, not a substitute for the official text or professional legal assessment.
Interpretation and limits for ASEAN
This substance is not unrestricted: cosmetic use is subject to the conditions in the cited official record.
Check product type, body area, concentration, purity and warning requirements before deciding whether a formulation is compliant.
How to interpret the legal role
The cited row forms part of a binding rule or legally incorporated list for this market.
Evidence on this page
- Recorded outcome: Restricted
- Legal role: Binding rule
- Source version: 2026-1
What it does not prove
Regional annex coverage does not replace member-state implementation dates, notifications or national deviations.
Further authoritative substance research
These sources can add identity, safety, exposure or hazard context. A link is not evidence that the database contains this exact substance, and none of these sources overrides the market decision above.
Cosmetic Ingredient Review safety assessments
Expert Panel conclusions, assessed ingredient groups, use conditions, dates and report documents
Independent expert review considered by FDA; not a government approval or binding market rule
Research this identity at the sourceFDA Global Substance Registration System
UNII identifiers, preferred names, substance types, codes and public substance relationships
Identity registry only; UNII availability does not imply FDA review or approval
Research this identity at the sourceILO/WHO International Chemical Safety Cards
Hazards, symptoms, first aid, storage, incompatibilities and physical properties for covered chemicals
International occupational chemical-safety reference; not cosmetic-use approval
Research this identity at the sourceJapan NITE-CHRIP
Chemical identity, Japanese and foreign legal lists, GHS hazards and exposure-related information
Chemical-management evidence; cosmetic status remains governed by the applicable MHLW standard and market rules
Research this identity at the sourceNIOSH Pocket Guide to Chemical Hazards
REL, PEL, IDLH, properties, exposure routes, symptoms, target organs, first aid and measurement methods for covered workplace chemicals
US occupational-health guidance and limits; not a cosmetic ingredient decision
Research this identity at the sourceOECD eChemPortal
Gateway to authority-owned physical-property, fate, ecotoxicity, toxicity, exposure and GHS records
Discovery gateway; each linked authority remains responsible for its data
Research this identity at the sourceUS EPA CompTox CTX APIs
API key required for importDTXSID identity, experimental and predicted properties, toxicity, bioactivity, exposure and environmental data
Scientific and computational evidence; predictions must remain labelled and do not determine cosmetic legality
Research this identity at the source