What function does SODIUM 3-HYDROXYBUTYRATE serve in cosmetics?

According to the EU CosIng inventory, SODIUM 3-HYDROXYBUTYRATE carries the following function designation(s): ANTI-SEBUM, PLASTICISER, SKIN CONDITIONING - HUMECTANT, SKIN CONDITIONING - MISCELLANEOUS.

What other records share CAS 13613-65-5?

CAS 13613-65-5 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains SODIUM 3-HYDROXYBUTYRATE?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef cosing-live-999272023-05-23

SODIUM 3-HYDROXYBUTYRATE

Sodium 3-Hydroxybutyrate is the organic compound that conforms to the formula:

SODIUM 3-HYDROXYBUTYRATE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 13613-65-5

CAS 13613-65-5PubChem CID 23679703

Sodium (R)-3-hydroxybutanoate

IUPAC name: sodium (3R)-3-hydroxybutanoate

Molecular formula: C4H7NaO3
Molecular weight: 126.09 g/mol
Exact mass: 126.02928836 Da
Topological polar surface area: 60.4 Å²
Hydrogen-bond donors: 1
Hydrogen-bond acceptors: 3
Covalent units: 2
Defined stereocentres: 1

Also known as

RefChem:1098617(R)-(-)-Sodium 3-hydroxybutyrate(R)-(-)-3-Hydroxybutyric acid sodium saltsodium;(3R)-3-hydroxybutanoate(R)-3-Hydroxybutanoic acid sodiumC4H7NaO3(R)-3-Hydroxybutanoic acid (sodium)AS-19989

16 more reported names

(R)-(-)-3-Hydroxybutyric Acid Sodium Salt(R)-3-hydroxybutyric acid sodium(R)-(+)-3-Hydroxybutyric acid, sodium saltSodium(R)-3-hydroxybutanoateButanoic acid, 3-hydroxy-, monosodium salt, (3R)-(+/-)-Sodium 3-hydroxybutyrateNBPUSGBJDWCHKC-AENDTGMFSA-MHMS2230C15(R)-3-Hydroxybutyric acid (sodium)CS-W016567DS-1679HY-W015851(R)-(-)-3-Hydroxybutanoic acid sodiumAS-19514J-524248(R)-(-)-3-Hydroxybutanoic acid sodium;(R)-3-Hydroxybutyric acid sodium

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEMBL:CHEMBL1475473
EPA DTXSID:DTXSID20929269
PubMed:8845

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Official European Commission record

CosIng substance ID: 99927
Entry status: Active
Published in the Official Journal: Yes
Recorded by the Commission: 2023-05-23

Open this entry in the official CosIng database

Fields as published by the European Commission. The link opens the entry itself, not a search for it.

Inventory details for SODIUM 3-HYDROXYBUTYRATE

INCI name

SODIUM 3-HYDROXYBUTYRATE

Description

Sodium 3-Hydroxybutyrate is the organic compound that conforms to the formula:

Record provenance

Inventory reference: cosing-live-99927
Imported identity: SODIUM 3-HYDROXYBUTYRATE
Source update: 2023-05-23

European Commission CosIng source notes

Annex records for SODIUM 3-HYDROXYBUTYRATE

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Key data

CAS

13613-65-5

—

Restriction

—

Function

ANTI-SEBUM: Helping control sebum production.
PLASTICISER: Softening and making supple synthetic polymers that otherwise could not be easily deformed, spread or worked out.
SKIN CONDITIONING - HUMECTANT: Increasing the water content of the top layers of the skin. Humectants are primarily hygroscopic agents drawing moisture from the surrounding air.
SKIN CONDITIONING - MISCELLANEOUS: Enhancing the appearance of dry and/or damaged skin by reducing flaking and restoring suppleness.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#26226 · SODIUM 3-HYDROXYBUTYRATE

Ingredients with overlapping formulation functions

PPG-3 BENZYL ETHER MYRISTATEPLASTICISER, SKIN CONDITIONING - EMOLLIENT, SOLVENT, UV ABSORBER

PPG-35/PPG-51 GLYCERYL ETHER/IPDI CROSSPOLYMERPLASTICISER, SKIN CONDITIONING

PROPANEDIOL DIPOLYRICINOLEATEADHESIVE, BINDING, PLASTICISER, VISCOSITY CONTROLLING

RHIZOBIAN GUMFILM FORMING, HAIR FIXING, PLASTICISER, VISCOSITY CONTROLLING

STYRENE/ACRYLATES COPOLYMER/POLYURETHANEBINDING, FILM FORMING, PLASTICISER

SUCROSE ACETATE ISOBUTYRATEFILM FORMING, PLASTICISER

SUCROSE BENZOATEFILM FORMING, PLASTICISER

TILIA TOMENTOSA BUD EXTRACTHAIR CONDITIONING, PLASTICISER, SKIN CONDITIONING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How SODIUM 3-HYDROXYBUTYRATE appears in the CosIng inventory

The CosIng inventory lists SODIUM 3-HYDROXYBUTYRATE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

SODIUM 3-HYDROXYBUTYRATE is also tagged with 4 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

SODIUM 3-HYDROXYBUTYRATE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, SODIUM 3-HYDROXYBUTYRATE carries the following function designation(s):

CAS 13613-65-5 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for SODIUM 3-HYDROXYBUTYRATE

This page reproduces the CosIng inventory entry for SODIUM 3-HYDROXYBUTYRATE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research SODIUM 3-HYDROXYBUTYRATE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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