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InventoryRef cosing-live-995912023-05-23

VITEXIN

Vitexin is a organic compound that conforms to the formula:

VITEXIN is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

Chemical identity and properties

PubChem 2D chemical structure for CAS 3681-93-4
CAS 3681-93-4PubChem CID 5280441

Vitexin

Vitexin is an apigenin flavone glycoside, which is found in the passion flower, bamboo leaves and pearl millet. It has a role as an antineoplastic agent, a platelet aggregation inhibitor, an EC 3.2.1.20 (alpha-glucosidase) inhibitor and a plant metabolite. It is a C-glycosyl compound and a trihydroxyflavone. It is functionally related to an apigenin. It is a conjugate acid of a vitexin-7-olate. — ChEBI

IUPAC name
5,7-dihydroxy-2-(4-hydroxyphenyl)-8-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]chromen-4-one
Molecular formula
C21H20O10
Molecular weight
432.4 g/mol
Exact mass
432.10564683 Da
XLogP3
0.2
Topological polar surface area
177.0 Ų
Hydrogen-bond donors
7
Hydrogen-bond acceptors
10
Covalent units
1
Defined stereocentres
5

Also known as

Apigenin 8-C-glucoside9VP70K75OKCHEBI:169544H-1-Benzopyran-4-one, 8-beta-D-glucopyranosyl-5,7-dihydroxy-2-(4-hydroxyphenyl)-8-glycosylapigenin(1S)-1,5-anhydro-1-[5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-8-yl]-D-glucitol8-glycosyl-apigenin(1S)-1,5-anhydro-1-(5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-8-yl)-D-glucitol
16 more reported names
5,7-dihydroxy-2-(4-hydroxyphenyl)-8-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl)chromen-4-oneRefChem:53003apigenin-8-c-beta-d-glucopyranoside222-963-8Apigenin-8-C-glucoside8-beta-D-Glucopyranosyl-apigenin5,7-dihydroxy-2-(4-hydroxyphenyl)-8-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)-4H-chromen-4-oneC21H20O10ORIENTOSIDEVITEXINEFlavone, 8-D-glucosyl-4',5,7-trihydroxy-8-beta-D-Glucopyranosyl-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one4H-1-Benzopyran-4-one, 5,7-dihydroxy-8-beta-D-glucopyranosyl-2-(4-hydroxyphenyl)-AS-559094H-1-Benzopyran-4-one, 8-.beta.-D-glucopyranosyl-5,7-dihydroxy-2-(4-hydroxyphenyl)-5,7-dihydroxy-2-(4-hydroxyphenyl)-8-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]chromen-4-one
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Official European Commission record

CosIng substance ID
99591
Entry status
Active
Published in the Official Journal
Yes
Recorded by the Commission
2023-05-23
Open this entry in the official CosIng database

Fields as published by the European Commission. The link opens the entry itself, not a search for it.

Inventory details for VITEXIN

INCI name

VITEXIN

Description

Vitexin is a organic compound that conforms to the formula:

Record provenance

Inventory reference
cosing-live-99591
Imported identity
VITEXIN
Source update
2023-05-23
European Commission CosIng source notes

Key data

Restriction
—
Function
ANTIOXIDANT
Inhibiting reactions promoted by oxygen, thus avoiding oxidation and rancidity.
HUMECTANT
Retaining and/or preserving the moisture in a product during use.
SKIN PROTECTING
Helping to avoid harmful effects to the skin from external factors.
SKIN CONDITIONING - HUMECTANT
Increasing the water content of the top layers of the skin. Humectants are primarily hygroscopic agents drawing moisture from the surrounding air.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

Ingredients with overlapping formulation functions

Additional official and scientific sources

11 external databases to check this identity in

How VITEXIN appears in the CosIng inventory

The CosIng inventory lists VITEXIN as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

VITEXIN is also tagged with 4 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

VITEXIN is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, VITEXIN carries the following function designation(s):

CAS 3681-93-4 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

Source note for VITEXIN

This page reproduces the CosIng inventory entry for VITEXIN from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research VITEXIN and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

Tools & next steps

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