What function does BIS-(MALEIMIDOETHOXY) ETHANE serve in cosmetics?

According to the EU CosIng inventory, BIS-(MALEIMIDOETHOXY) ETHANE carries the following function designation(s): BINDING, HAIR CONDITIONING, HAIR DYEING, HAIR FIXING, HAIR WAVING OR STRAIGHTENING, OXIDISING, SURFACE MODIFIER, SKIN CONDITIONING - MISCELLANEOUS.

What other records share CAS 115597-84-7?

CAS 115597-84-7 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains BIS-(MALEIMIDOETHOXY) ETHANE?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef cosing-live-995302023-05-23

BIS-(MALEIMIDOETHOXY) ETHANE

Bis-(Maleimidoethoxy) Ethane is the organic compound that conforms to the formula:

BIS-(MALEIMIDOETHOXY) ETHANE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 115597-84-7

CAS 115597-84-7PubChem CID 3690297

Bis-(maleimidoethoxy) ethane

IUPAC name: 1-[2-[2-[2-(2,5-dioxopyrrol-1-yl)ethoxy]ethoxy]ethyl]pyrrole-2,5-dione

Molecular formula: C14H16N2O6
Molecular weight: 308.29 g/mol
Exact mass: 308.10083623 Da
XLogP3: -1.6
Topological polar surface area: 93.2 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 6
Covalent units: 1
Defined stereocentres: 0

Also known as

1,8-Bis(maleimido)-3,6-dioxaoctaneLiqwdBM(peg)21,8-Bismaleimidotriethyleneglycol1,2-bis(2-maleimidoethoxy)ethaneR20U86RE9F1H-Pyrrole-2,5-dione, 1,1'-[1,2-ethanediylbis(oxy-2,1-ethanediyl)]bis-1,1'-((Ethan-1,2-diylbis(oxy))bis(ethan-2,1-diyl))bis(1H-pyrrol-2,5-dione)

16 more reported names

1H-Pyrrole-2,5-dione, 1,1'-(1,2-ethanediylbis(oxy-2,1-ethanediyl))bis-RefChem:10799991,8-Bis(maleimido)triethyleneglycol1,8-Bis-maleimidotriethyleneglycol1,8-Bis-maleimido-(PEO)31,1'-((ethane-1,2-diylbis(oxy))bis(ethane-2,1-diyl))bis(1H-pyrrole-2,5-dione)1-(2-{2-[2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy]ethoxy}ethyl)-2,5-dihydro-1H-pyrrole-2,5-dione1,8-Bis-maleimidotetraethyleneglycolUNII-R20U86RE9F1,1'-[ethane-1,2-Diylbis(Oxyethane-2,1-Diyl)]bis(1h-Pyrrole-2,5-Dione)1,8-bis-maleimidodiethyleneglycolBis-(maleimidoethoxy) ethane [INCI]Bis-PEG2-MalMal-PEG2-CH2CH2MalFERLGYOHRKHQJP-UHFFFAOYSA-N1,8-Bismaleimido diethylene glycol

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEMBL:CHEMBL575383
EPA DTXSID:DTXSID20921768

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Official European Commission record

CosIng substance ID: 99530
Entry status: Active
Published in the Official Journal: Yes
Recorded by the Commission: 2023-05-23

Open this entry in the official CosIng database

Fields as published by the European Commission. The link opens the entry itself, not a search for it.

Inventory details for BIS-(MALEIMIDOETHOXY) ETHANE

INCI name

BIS-(MALEIMIDOETHOXY) ETHANE

Description

Bis-(Maleimidoethoxy) Ethane is the organic compound that conforms to the formula:

Record provenance

Inventory reference: cosing-live-99530
Imported identity: BIS-(MALEIMIDOETHOXY) ETHANE
Source update: 2023-05-23

European Commission CosIng source notes

Annex records for BIS-(MALEIMIDOETHOXY) ETHANE

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Key data

CAS

115597-84-7

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Restriction

—

Function

BINDING: Providing adhesive properties during and after compression in cosmetic tablets and/or cakes.
HAIR CONDITIONING: Enhancing the appearance and feel of hair. Leaving the hair easy to comb, supple, soft and shiny and/or imparting volume, lightness, gloss, texture, etc.
HAIR DYEING: Imparting color to hair. Hair dyeing preparations may be temporary, semi-permanent, or permanent, depending on the length of time the colorant remains on the hair.
HAIR FIXING: Permitting physical control of hair style.
HAIR WAVING OR STRAIGHTENING: Modifying the chemical structure of the hair, allowing it to be set in the style required (permanent waves or hair straightening).
OXIDISING: Changing the chemical nature of another ingredient by adding oxygen (or removing hydrogen).
SURFACE MODIFIER: Applied to other cosmetic components to make them more hydrophilic or hydrophobic, or to modify their physical/chemical properties.
SKIN CONDITIONING - MISCELLANEOUS: Enhancing the appearance of dry and/or damaged skin by reducing flaking and restoring suppleness.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#3473 · BIS-(MALEIMIDOETHOXY) ETHANE

Ingredients with overlapping formulation functions

ASTER YOMENA EXTRACTSKIN CONDITIONING, SOLVENT, SURFACE MODIFIER, UV FILTER

BEHENYL CANNABIS SEEDATESKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SLIP MODIFIER, SURFACE MODIFIER

C12-17 ALKYL KETENE DIMERHAIR CONDITIONING, HAIR FIXING, SKIN CONDITIONING, SURFACE MODIFIER

CANNABIDIETH-21SKIN CONDITIONING - EMOLLIENT; EMULSION STABILISING; FILM FORMING; FRAGRANCE; ORAL CARE; PERFUMING;…

CANNABIS SEED OIL DIMER DILINOLEYL ESTERS/DIMER DILINOLEATE COPOLYMERBINDING, FILM FORMING, SKIN CONDITIONING, SKIN PROTECTING, SURFACE MODIFIER

CAPRYL CANNABIS SEEDATESKIN CONDITIONING, SLIP MODIFIER, SURFACE MODIFIER

DILINOLEAMIDOPROPYL DIMONIUM DIMER DILINOLEATEEMULSION STABILISING; FILM FORMING; SURFACE MODIFIER

GOLDCOLORANT, SKIN CONDITIONING - MISCELLANEOUS, SLIP MODIFIER, SURFACE MODIFIER

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How BIS-(MALEIMIDOETHOXY) ETHANE appears in the CosIng inventory

The CosIng inventory lists BIS-(MALEIMIDOETHOXY) ETHANE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

BIS-(MALEIMIDOETHOXY) ETHANE is also tagged with 8 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

BIS-(MALEIMIDOETHOXY) ETHANE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, BIS-(MALEIMIDOETHOXY) ETHANE carries the following function designation(s):

CAS 115597-84-7 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

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Source note for BIS-(MALEIMIDOETHOXY) ETHANE

This page reproduces the CosIng inventory entry for BIS-(MALEIMIDOETHOXY) ETHANE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research BIS-(MALEIMIDOETHOXY) ETHANE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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