Is ISOMALTULOSE safe to use in EU cosmetics?

ISOMALTULOSE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Always verify against the current official CosIng database before formulating.

What function does ISOMALTULOSE serve in cosmetics?

According to the EU CosIng inventory, ISOMALTULOSE carries the following function designation(s): SKIN CONDITIONING - HUMECTANT, SKIN CONDITIONING - MISCELLANEOUS.

How do I check if my formula contains ISOMALTULOSE?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef cosing-live-989022023-05-23

ISOMALTULOSE

Isomaltulose is the disaccharide which consists of Glucose and Fructose linked by an -1,6-glycosidic bond.

ISOMALTULOSE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

Markets and their official sources Search every market for this name

Chemical identity and properties

PubChem 2D chemical structure for CAS 13718-94-0

CAS 13718-94-0PubChem CID 83686

Palatinose

IUPAC name: (3S,4R,5R)-1,3,4,5-tetrahydroxy-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexan-2-one

Molecular formula: C12H22O11
Molecular weight: 342.30 g/mol
Exact mass: 342.11621151 Da
XLogP3: -4.8
Topological polar surface area: 197.0 Å²
Hydrogen-bond donors: 8
Hydrogen-bond acceptors: 11
Covalent units: 1
Defined stereocentres: 8

Also known as

V59P50X4UYISOMALTULOSE ANHYDROUSRefChem:169603GlyTouCan:G91589FQ6-O alpha-D-glucosylpyranosyl-D-fructose237-282-1(2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-(((2R,3S,4S)-3,4,5-trihydroxy-5-(hydroxymethyl)oxolan-2-yl)methoxy)oxane-3,4,5-triol(2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-(((2R,3S,4S)-5-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxolan-2-yl)methoxy)oxane-3,4,5-triol

16 more reported names

6-O alpha-D-glucopyranosyl-D-fructose6-O-alpha-D-Glucopyranosyl-D-fructofuranoseCHEBI:18394Isomaltulose6-O-alpha-D-Glucopyranosyl-D-fructoseD-Fructose, 6-O-alpha-D-glucopyranosyl-D-Fructose, 6-O-alpha-D-glucopyranosyl-, hydrate6-O-a-D-Glucopyranosyl-D-fructose; Isomaltulose(3S,4R,5R)-1,3,4,5-Tetrahydroxy-6-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexan-2-oneEINECS 237-282-1(3S,4R,5R)-1,3,4,5-tetrahydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}hexan-2-one6-Oalpha-D-Glucosylpyranosyl-D-fructoseISOMALTULOSE [MI]UNII-V59P50X4UYMSK3236RJPPRBMGVWEZRR-WTZPKTTFSA-N

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

EPA DTXSID:DTXSID90929736

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 58024-13-8

CAS 58024-13-8PubChem CID 52994241

Isomaltulose monohydrate

IUPAC name: (2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-[[(2R,3S,4S)-3,4,5-trihydroxy-5-(hydroxymethyl)oxolan-2-yl]methoxy]oxane-3,4,5-triol;hydrate

Molecular formula: C12H24O12
Molecular weight: 360.31 g/mol
Exact mass: 360.12677620 Da
Topological polar surface area: 191.0 Å²
Hydrogen-bond donors: 9
Hydrogen-bond acceptors: 12
Covalent units: 2
Defined stereocentres: 8

Also known as

D-Fructose, 6-O-alpha-d-glucopyranosyl-, monohydrate6-O-alpha-D-glucopyranosyl-d-fructofuranose monohydrateRefChem:149523Palatinose monohydratePalatinose hydrateUNII-43360LXH8NPalatinose (hydrate)(2r,3s,4s,5r,6s)-2-(hydroxymethyl)-6-(((2r,3s,4s)-3,4,5-trihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)methoxy)tetrahydro-2h-pyran-3,4,5-triol hydrate

7 more reported names

Palatinose hydrate, >=99%XZKUCJJNNDINKX-HGLHLWFZSA-NPalatinose hydrate, analytical standardT48756-O-alpha-D-Glucopyranosyl-D-fructofuranose--water (1/1)6-O-| cent-D-Glucopyranosyl-D-fructose, Isomaltulose hydrate(2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-[[(2R,3S,4S)-3,4,5-trihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]methoxy]tetrahydropyran-3,4,5-triol;hydrate

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

EPA DTXSID:DTXSID40206746

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Official European Commission record

CosIng substance ID: 98902
Entry status: Active
Published in the Official Journal: Yes
Recorded by the Commission: 2023-05-23

Open this entry in the official CosIng database

Fields as published by the European Commission. The link opens the entry itself, not a search for it.

Inventory details for ISOMALTULOSE

INCI name

ISOMALTULOSE

Description

Isomaltulose is the disaccharide which consists of Glucose and Fructose linked by an -1,6-glycosidic bond.

Record provenance

Inventory reference: cosing-live-98902
Imported identity: ISOMALTULOSE
Source update: 2023-05-23

European Commission CosIng source notes

Annex records for ISOMALTULOSE

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Key data

CAS

13718-94-0; 58024-13-8 (monohydrate)

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Restriction

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Function

SKIN CONDITIONING - HUMECTANT: Increasing the water content of the top layers of the skin. Humectants are primarily hygroscopic agents drawing moisture from the surrounding air.
SKIN CONDITIONING - MISCELLANEOUS: Enhancing the appearance of dry and/or damaged skin by reducing flaking and restoring suppleness.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#13783 · ISOMALTULOSE

Ingredients with overlapping formulation functions

IDEBENONYL NICOTINATEANTIOXIDANT; HAIR CONDITIONING; PRESERVATIVE; SKIN PROTECTING; SKIN CONDITIONING - HUMECTANT; SKIN …

ILEX CORNUTA LEAF EXTRACTSKIN CONDITIONING - HUMECTANT

INDIRUBINSKIN CONDITIONING - EMOLLIENT; SKIN PROTECTING; SKIN CONDITIONING - HUMECTANT

IRPEX LACTEUS FERMENT FILTRATE EXTRACTHAIR CONDITIONING; SKIN PROTECTING; SKIN CONDITIONING - HUMECTANT

ISOTRIACONTANEANTIOXIDANT, ASTRINGENT, HAIR CONDITIONING, HUMECTANT, SKIN CONDITIONING - EMOLLIENT, SKIN CONDITIO…

JOJOBA OIL PROPANEDIOL ESTERSEMULSION STABILISING, HAIR CONDITIONING, HUMECTANT, SKIN CONDITIONING - EMOLLIENT, SKIN CONDITIONIN…

JUGLANS MANDSHURICA BARK EXTRACTSKIN CONDITIONING - HUMECTANT

JUNCUS DECIPIENS STEM WATERHUMECTANT; SKIN CONDITIONING - HUMECTANT

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How ISOMALTULOSE appears in the CosIng inventory

The CosIng inventory lists ISOMALTULOSE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

ISOMALTULOSE is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

ISOMALTULOSE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, ISOMALTULOSE carries the following function designation(s):

CAS 13718-94-0; 58024-13-8 (monohydrate) may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

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Source note for ISOMALTULOSE

This page reproduces the CosIng inventory entry for ISOMALTULOSE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research ISOMALTULOSE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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