Is SENKYUNOLIDE A safe to use in EU cosmetics?

SENKYUNOLIDE A is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Always verify against the current official CosIng database before formulating.

What other records share CAS 63038-10-8?

CAS 63038-10-8 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains SENKYUNOLIDE A?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef cosing-live-988662023-05-22

SENKYUNOLIDE A

Senkyunolide A is the organic compound that conforms to the formula:

SENKYUNOLIDE A is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 63038-10-8

CAS 63038-10-8PubChem CID 3085257

3-N-butyl-4,5-dihydrophthalide, (S)-

Senkyunolide is a member of 2-benzofurans. — ChEBI

IUPAC name: (3S)-3-butyl-4,5-dihydro-3H-2-benzofuran-1-one

Molecular formula: C12H16O2
Molecular weight: 192.25 g/mol
Exact mass: 192.115029749 Da
XLogP3: 2.7
Topological polar surface area: 26.3 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 2
Covalent units: 1
Defined stereocentres: 1

Also known as

RefChem:47695Senkyunolide ASenkyunolideSedanenolide(S)-Sedanenolide(-)-Sedanenolide(S)-3-Butyl-4,5-dihydroisobenzofuran-1(3H)-one(3S)-3-Butyl-4,5-dihydro-1(3H)-isobenzofuranone

16 more reported names

1(3H)-Isobenzofuranone, 3-butyl-4,5-dihydro-, (S)-74QZK813SO(3S)-3-butyl-1,3,4,5-tetrahydro-2-benzofuran-1-one(3S)-3-BUTYL-4,5-DIHYDRO-2-BENZOFURAN-1(3H)-ONEUNII-74QZK813SOSenkyunolide-A(3S)-3-butyl-4,5-dihydro-3H-isobenzofuran-1-one4,5-Dihydro-3-butylphthalide1(3H)-Isobenzofuranone, 3-butyl-4,5-dihydro-, (3S)-CHEBI:179916ZPIKVDODKLJKIN-NSHDSACASA-NHY-N0743TN4991EBC-617189MS-23041CS-0009775

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:179916
EPA DTXSID:DTXSID40212322

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Official European Commission record

CosIng substance ID: 98866
Entry status: Active
Published in the Official Journal: Yes
Recorded by the Commission: 2023-05-22

Open this entry in the official CosIng database

Fields as published by the European Commission. The link opens the entry itself, not a search for it.

Inventory details for SENKYUNOLIDE A

INCI name

SENKYUNOLIDE A

Description

Senkyunolide A is the organic compound that conforms to the formula:

Record provenance

Inventory reference: cosing-live-98866
Imported identity: SENKYUNOLIDE A
Source update: 2023-05-22

European Commission CosIng source notes

Annex records for SENKYUNOLIDE A

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Key data

CAS

63038-10-8

—

Restriction

—

Function

SKIN CONDITIONING - EMOLLIENT: Acting as lubricants on the skin surface providing the skin with a soft and smooth appearance.
SKIN PROTECTING: Helping to avoid harmful effects to the skin from external factors.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#25599 · SENKYUNOLIDE A

Ingredients with overlapping formulation functions

SEAL OILSKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SKIN PROTECTING

SECALE CEREALE PHYTOPLACENTA EXTRACTSKIN CONDITIONING, SKIN PROTECTING

SEDUM FORMOSANUM FLOWER/LEAF/STEM EXTRACTANTIOXIDANT, SKIN CONDITIONING, SKIN PROTECTING

SELENICEREUS MONACANTHUS BUD EXTRACTANTIOXIDANT, BLEACHING, SKIN CONDITIONING, SKIN PROTECTING

SEPIA EXTRACTSKIN CONDITIONING, SKIN PROTECTING

SEQUOIA SEMPERVIRENS LEAF CELL EXTRACTFRAGRANCE, SKIN PROTECTING

SEQUOIADENDRON GIGANTEUM BUD EXTRACTSKIN PROTECTING

SEQUOIADENDRON GIGANTEUM CALLUS CULTURE EXTRACTANTIOXIDANT, HAIR CONDITIONING, HUMECTANT, SKIN PROTECTING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How SENKYUNOLIDE A appears in the CosIng inventory

The CosIng inventory lists SENKYUNOLIDE A as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

SENKYUNOLIDE A is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

SENKYUNOLIDE A is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, SENKYUNOLIDE A carries the following function designation(s):

CAS 63038-10-8 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

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Source note for SENKYUNOLIDE A

This page reproduces the CosIng inventory entry for SENKYUNOLIDE A from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research SENKYUNOLIDE A and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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Tools & next steps

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