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InventoryRef cosing-live-416012023-05-22

2,2'-METHYLENEBIS 4-AMINOPHENOL

2,2'-METHYLENEBIS 4-AMINOPHENOL is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

Chemical identity and properties

PubChem 2D chemical structure for CAS 63969-46-0
CAS 63969-46-0PubChem CID 10176981

2,2'-Methylenebis(4-aminophenol)

IUPAC name
4-amino-2-[(5-amino-2-hydroxyphenyl)methyl]phenol
Molecular formula
C13H14N2O2
Molecular weight
230.26 g/mol
Exact mass
230.105527694 Da
XLogP3
1.6
Topological polar surface area
92.5 Ų
Hydrogen-bond donors
4
Hydrogen-bond acceptors
4
Covalent units
1
Defined stereocentres
0

Also known as

2,2'-Methylenebis 4-aminophenolBis-(5-amino-2-hydroxyphenyl)-methanUNII-433B39S4812,2'-Methylenebis 4-aminophenol [INCI]433B39S481RefChem:807472,2'-methylenebis-4-aminophenol
External database identifiers

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Official European Commission record

CosIng substance ID
41601
Entry status
Active
Published in the Official Journal
Yes
Recorded by the Commission
2023-05-22
Open this entry in the official CosIng database

Fields as published by the European Commission. The link opens the entry itself, not a search for it.

Inventory details for 2,2'-METHYLENEBIS 4-AMINOPHENOL

INCI name

2,2'-METHYLENEBIS 4-AMINOPHENOL

Record provenance

Inventory reference
cosing-live-41601
Imported identity
2,2'-METHYLENEBIS 4-AMINOPHENOL
Source update
2023-05-22
European Commission CosIng source notes

Key data

Restriction
—
Function
HAIR DYEING
Imparting color to hair. Hair dyeing preparations may be temporary, semi-permanent, or permanent, depending on the length of time the colorant remains on the hair.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

Records sharing a CAS or EC identity

Ingredients with overlapping formulation functions

Additional official and scientific sources

11 external databases to check this identity in

How 2,2'-METHYLENEBIS 4-AMINOPHENOL appears in the CosIng inventory

The CosIng inventory lists 2,2'-METHYLENEBIS 4-AMINOPHENOL as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

2,2'-METHYLENEBIS 4-AMINOPHENOL is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

2,2'-METHYLENEBIS 4-AMINOPHENOL is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, 2,2'-METHYLENEBIS 4-AMINOPHENOL carries the following function designation(s):

CAS 63969-46-0 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

Source note for 2,2'-METHYLENEBIS 4-AMINOPHENOL

This page reproduces the CosIng inventory entry for 2,2'-METHYLENEBIS 4-AMINOPHENOL from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research 2,2'-METHYLENEBIS 4-AMINOPHENOL and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

Tools & next steps

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