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InventoryRef cosing-live-1052462024-08-26

PYRROLOPIPERAZINEDIONE

Pyrrolopiperazinedione is the organic compound that conforms to the formula:

PYRROLOPIPERAZINEDIONE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

Chemical identity and properties

PubChem 2D chemical structure for CAS 19179-12-5
CAS 19179-12-5PubChem CID 193540

Cyclo(glycylprolyl)

Hexahydropyrrolo[1,2-a]pyrazine-1,4-dione is an organonitrogen compound and an organooxygen compound. It is functionally related to an alpha-amino acid. — ChEBI

IUPAC name
2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
Molecular formula
C7H10N2O2
Molecular weight
154.17 g/mol
Exact mass
154.074227566 Da
XLogP3
-0.6
Topological polar surface area
49.4 Ų
Hydrogen-bond donors
1
Hydrogen-bond acceptors
2
Covalent units
1
Defined stereocentres
0

Also known as

Cyclo(gly-pro)Cyclo(gly-O-pro)RefChem:580191Hexahydropyrrolo[1,2-a]pyrazine-1,4-dioneoctahydropyrrolo[1,2-a]piperazine-1,4-dioneCHEBI:181570Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-HMS3604O06
15 more reported names
Cyclo-Gly-Pro, >=98% (GC/HPLC)Cyclo(glycyl-L-prolyl)CS-0054025Octahydropyrrolo[1,2-a]pyrazine-1,4-dioneHMS1629L11EBC-47338TN6674HY-W062171NSC-615303Hexahydropyrrolo[12-a]pyrazine-14-dioneAS-50420Pyrrolidino[1,2-a]piperazine-3,6-dioneDB-025064EN300-73039Pyrrolo(1,2-a)pyrazine-1,4-dione, hexahydro-, (S)-
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Official European Commission record

CosIng substance ID
105246
Entry status
Active
Published in the Official Journal
Yes
Recorded by the Commission
2024-08-26
Open this entry in the official CosIng database

Fields as published by the European Commission. The link opens the entry itself, not a search for it.

Inventory details for PYRROLOPIPERAZINEDIONE

INCI name

PYRROLOPIPERAZINEDIONE

Description

Pyrrolopiperazinedione is the organic compound that conforms to the formula:

Record provenance

Inventory reference
cosing-live-105246
Imported identity
PYRROLOPIPERAZINEDIONE
Source update
2024-08-26
European Commission CosIng source notes

Key data

Restriction
—
Function
SKIN CONDITIONING - MISCELLANEOUS
Enhancing the appearance of dry and/or damaged skin by reducing flaking and restoring suppleness.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

Ingredients with overlapping formulation functions

Additional official and scientific sources

11 external databases to check this identity in

How PYRROLOPIPERAZINEDIONE appears in the CosIng inventory

The CosIng inventory lists PYRROLOPIPERAZINEDIONE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

PYRROLOPIPERAZINEDIONE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

PYRROLOPIPERAZINEDIONE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, PYRROLOPIPERAZINEDIONE carries the following function designation(s):

CAS 19179-12-5 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

Source note for PYRROLOPIPERAZINEDIONE

This page reproduces the CosIng inventory entry for PYRROLOPIPERAZINEDIONE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research PYRROLOPIPERAZINEDIONE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

Tools & next steps

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