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InventoryRef cosing-live-1042592024-08-13

SH-POLYPEPTIDE-155

sh-Polypeptide-155 is a single chain recombinant human peptide, produced by fermentation in E. coli. The starting gene which is a synthesized copy of the human gene that codes for Hyaluronan and Proteoglycan Link Protei…

SH-POLYPEPTIDE-155 is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

What the official INCI name states

The official label identifies a peptide- or protein-related cosmetic material.

Identity type from wording
peptide_or_protein

This structure is derived only from the official label wording. It does not establish composition, concentration, chemical equivalence, safety or regulatory permission.

Official European Commission record

CosIng substance ID
104259
Published in the Official Journal
Yes
Recorded by the Commission
2024-08-13
Open this entry in the official CosIng database

Fields as published by the European Commission. The link opens the entry itself, not a search for it.

Inventory details for SH-POLYPEPTIDE-155

INCI name

SH-POLYPEPTIDE-155

Description

sh-Polypeptide-155 is a single chain recombinant human peptide, produced by fermentation in E. coli. The starting gene which is a synthesized copy of the human gene that codes for Hyaluronan and Proteoglycan Link Protein 1 is used as such or adapted to the production host. It contains a maximum of 354 amino acids which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of the 20 standard amino acids.

Record provenance

Inventory reference
cosing-live-104259
Imported identity
SH-POLYPEPTIDE-155
Source update
2024-08-13
European Commission CosIng source notes

Key data

CAS
—

The CosIng inventory records no CAS number for this ingredient. That is the absence of an identifier in the source, not a finding about the substance.

EC
—
Restriction
—
Function
HAIR CONDITIONING
Enhancing the appearance and feel of hair. Leaving the hair easy to comb, supple, soft and shiny and/or imparting volume, lightness, gloss, texture, etc.
HUMECTANT
Retaining and/or preserving the moisture in a product during use.
SKIN PROTECTING
Helping to avoid harmful effects to the skin from external factors.
SKIN CONDITIONING - MISCELLANEOUS
Enhancing the appearance of dry and/or damaged skin by reducing flaking and restoring suppleness.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

Ingredients with overlapping formulation functions

Additional official and scientific sources

11 external databases to check this identity in

How SH-POLYPEPTIDE-155 appears in the CosIng inventory

The CosIng inventory lists SH-POLYPEPTIDE-155 as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

SH-POLYPEPTIDE-155 is also tagged with 4 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

SH-POLYPEPTIDE-155 is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, SH-POLYPEPTIDE-155 carries the following function designation(s):

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

Source note for SH-POLYPEPTIDE-155

This page reproduces the CosIng inventory entry for SH-POLYPEPTIDE-155 from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research SH-POLYPEPTIDE-155 and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

Tools & next steps

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