What does the restriction note for HUMAN CORD BLOOD DERIVED STEM CELL EXOSOMES mean?

The restriction field for HUMAN CORD BLOOD DERIVED STEM CELL EXOSOMES reads: II/416. This is the restriction note from the CosIng inventory. For authoritative conditions and limits, always refer to the linked annex entries.

How do I check if my formula contains HUMAN CORD BLOOD DERIVED STEM CELL EXOSOMES?

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InventoryRef cosing-live-1041952024-01-18

HUMAN CORD BLOOD DERIVED STEM CELL EXOSOMES

Human Cord Blood Derived Stem Cell Exosomes are the vesicles secreted into the conditioned media by human cord blood derived stem cells.

HUMAN CORD BLOOD DERIVED STEM CELL EXOSOMES is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet. Inventory note: II/416.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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What the official INCI name states

The official label identifies a biological source material and its stated preparation or plant part.

Identity type from wording: biological_material
Preparation or form: EXOSOMES
Stated biological parts: STEM, CELL

Scientific-name candidates to verify against the supplier specification

Blood derived

This structure is derived only from the official label wording. It does not establish composition, concentration, chemical equivalence, safety or regulatory permission.

Official European Commission record

CosIng substance ID: 104195
Published in the Official Journal: Yes
Recorded by the Commission: 2024-01-18

Open this entry in the official CosIng database

Fields as published by the European Commission. The link opens the entry itself, not a search for it.

Inventory details for HUMAN CORD BLOOD DERIVED STEM CELL EXOSOMES

INCI name

HUMAN CORD BLOOD DERIVED STEM CELL EXOSOMES

Description

Human Cord Blood Derived Stem Cell Exosomes are the vesicles secreted into the conditioned media by human cord blood derived stem cells.

Record provenance

Inventory reference: cosing-live-104195
Imported identity: HUMAN CORD BLOOD DERIVED STEM CELL EXOSOMES
Source update: 2024-01-18

European Commission CosIng source notes

Annex records for HUMAN CORD BLOOD DERIVED STEM CELL EXOSOMES

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Key data

CAS

—

The CosIng inventory records no CAS number for this ingredient. That is the absence of an identifier in the source, not a finding about the substance.

—

Restriction

II/416

Function

ANTIOXIDANT: Inhibiting reactions promoted by oxygen, thus avoiding oxidation and rancidity.
SKIN PROTECTING: Helping to avoid harmful effects to the skin from external factors.
SKIN CONDITIONING - HUMECTANT: Increasing the water content of the top layers of the skin. Humectants are primarily hygroscopic agents drawing moisture from the surrounding air.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#12214 · HUMAN CORD BLOOD DERIVED STEM CELL EXOSOMES

Ingredients with overlapping formulation functions

HUMAN BLOOD DERIVED NATURAL KILLER CELL CONDITIONED MEDIA EXTRACTSKIN CONDITIONING - EMOLLIENT; SKIN CONDITIONING - HUMECTANT

HUMAN CARDIOMYOCYTE INDUCED PLURIPOTENT CELL CONDITIONED MEDIASKIN PROTECTING; SKIN CONDITIONING - HUMECTANT

HUMAN COLLAGENSKIN CONDITIONING - EMOLLIENT; SKIN CONDITIONING - HUMECTANT

HUMAN COLOSTRUM EXTRACTSKIN CONDITIONING - HUMECTANT

HUMAN CORD BLOOD INDUCED PLURIPOTENT CELL EXOSOMESSKIN CONDITIONING - HUMECTANT; SKIN CONDITIONING - MISCELLANEOUS

HUMAN CORD BLOOD STEM CELL CONDITIONED MEDIA EXTRACTANTIOXIDANT; SKIN PROTECTING; SKIN CONDITIONING - HUMECTANT

HUMAN DERMAL FIBROBLAST SPHEROID CONDITIONED MEDIASKIN CONDITIONING - HUMECTANT; SKIN CONDITIONING - MISCELLANEOUS

HUMAN DERMAL FIBROBLAST TELOMERASE EXOSOMESSKIN CONDITIONING - EMOLLIENT; HAIR CONDITIONING; SKIN PROTECTING; SKIN CONDITIONING - HUMECTANT

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How HUMAN CORD BLOOD DERIVED STEM CELL EXOSOMES appears in the CosIng inventory

The CosIng inventory lists HUMAN CORD BLOOD DERIVED STEM CELL EXOSOMES as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

HUMAN CORD BLOOD DERIVED STEM CELL EXOSOMES is also tagged with 3 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

HUMAN CORD BLOOD DERIVED STEM CELL EXOSOMES is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

The restriction field for HUMAN CORD BLOOD DERIVED STEM CELL EXOSOMES reads: "II/416". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, HUMAN CORD BLOOD DERIVED STEM CELL EXOSOMES carries the following function designation(s):

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Source note for HUMAN CORD BLOOD DERIVED STEM CELL EXOSOMES

This page reproduces the CosIng inventory entry for HUMAN CORD BLOOD DERIVED STEM CELL EXOSOMES from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research HUMAN CORD BLOOD DERIVED STEM CELL EXOSOMES and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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