Is TYROSOL safe to use in EU cosmetics?

TYROSOL is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Always verify against the current official CosIng database before formulating.

What function does TYROSOL serve in cosmetics?

According to the EU CosIng inventory, TYROSOL carries the following function designation(s): ANTIOXIDANT, ORAL CARE, SKIN CONDITIONING - MISCELLANEOUS.

What other records share CAS 501-94-0?

CAS 501-94-0 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains TYROSOL?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef cosing-live-1014692024-07-22

TYROSOL

Tyrosol is the organic compound that conforms to the formula:

TYROSOL is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 501-94-0

CAS 501-94-0PubChem CID 10393

Tyrosol

2-(4-hydroxyphenyl)ethanol is a phenol substituted at position 4 by a 2-hydroxyethyl group. It has a role as a geroprotector, an antioxidant, a cardiovascular drug, an anti-arrhythmia drug, a protective agent, a plant metabolite and a fungal metabolite. It is functionally related to a 2-phenylethanol. — ChEBI

IUPAC name: 4-(2-hydroxyethyl)phenol

Molecular formula: C8H10O2
Molecular weight: 138.16 g/mol
Exact mass: 138.068079557 Da
XLogP3: 0.4
Topological polar surface area: 40.5 Å²
Hydrogen-bond donors: 2
Hydrogen-bond acceptors: 2
Covalent units: 1
Defined stereocentres: 0

Also known as

2-(4-Hydroxyphenyl)ethanol4-Hydroxyphenethyl alcoholp-Hydroxyphenethyl alcohol4-Hydroxybenzeneethanol4-HydroxyphenylethanolBenzeneethanol, 4-hydroxy-p-Tyrosolp-hydroxyphenylethanol

16 more reported names

1AK4MU3SNXNSC-59876beta-(4-Hydroxyphenyl)ethanolCHEBI:1879n-tyrosolpara-hydroxyphenylethanolRefChem:50710207-930-8tyrosol acetate4-Hydroxyphenylethyl alcoholMetoprolol EP Impurity G2-(4-Hydroxyphenyl)ethyl Alcoholp-HPEA4-hydroxy-Benzeneethanolp-Thyrosolp-Hydroxyphenylethyl alcohol

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:1879
ChEMBL:CHEMBL53566
EPA DTXSID:DTXSID8060111
PubMed:23046443
PubMed:23018923
PubMed:23017390
PubMed:23016154
PubMed:23000970
PubMed:22963618
PubMed:22953817
PubMed:22944382
PubMed:22924436
PubMed:22898957
PubMed:22824366
PubMed:22816300

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Official European Commission record

CosIng substance ID: 101469
Published in the Official Journal: Yes
Recorded by the Commission: 2024-07-22

Open this entry in the official CosIng database

Fields as published by the European Commission. The link opens the entry itself, not a search for it.

Inventory details for TYROSOL

INCI name

TYROSOL

Description

Tyrosol is the organic compound that conforms to the formula:

Record provenance

Inventory reference: cosing-live-101469
Imported identity: TYROSOL
Source update: 2024-07-22

European Commission CosIng source notes

Annex records for TYROSOL

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Key data

CAS

501-94-0

207-930-8

Restriction

—

Function

ANTIOXIDANT: Inhibiting reactions promoted by oxygen, thus avoiding oxidation and rancidity.
ORAL CARE: Providing cosmetic effects to the oral cavity, e.g. cleansing, deodorising, protecting.
SKIN CONDITIONING - MISCELLANEOUS: Enhancing the appearance of dry and/or damaged skin by reducing flaking and restoring suppleness.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#29593 · TYROSOL

Ingredients with overlapping formulation functions

TRACHYSPERMUM AMMI FLOWER EXTRACTORAL CARE

TRICALCIUM PHOSPHATEABRASIVE, ANTICAKING, FRAGRANCE, OPACIFYING, ORAL CARE

TRIPEPTIDE-62ANTIOXIDANT, ANTIPLAQUE, ORAL CARE, SKIN PROTECTING

TRIPEPTIDE-96 HEXA-(PROLYL HYDROXYPROLYL GLYCYL) TRIPEPTIDE-97 PENTA-(PROLYL HY…ANTIOXIDANT; SKIN CONDITIONING - EMOLLIENT; HAIR CONDITIONING; NAIL CONDITIONING; ORAL CARE

VANILLYL BUTYL ETHERFRAGRANCE, HAIR CONDITIONING, ORAL CARE, SKIN CONDITIONING

VITIS VINIFERA SEED EXTRACTANTI-SEBORRHEIC, ANTIMICROBIAL, ANTIOXIDANT, ORAL CARE, SKIN PROTECTING, UV ABSORBER

ZANTHOXYLUM ALATUM FRUIT OILFRAGRANCE, ORAL CARE, SKIN CONDITIONING

ZINC ASCORBATEANTIOXIDANT, ORAL CARE, SKIN PROTECTING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How TYROSOL appears in the CosIng inventory

The CosIng inventory lists TYROSOL as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

TYROSOL is also tagged with 3 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

TYROSOL is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, TYROSOL carries the following function designation(s):

CAS 501-94-0 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

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Source note for TYROSOL

This page reproduces the CosIng inventory entry for TYROSOL from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research TYROSOL and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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Tools & next steps

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