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CAS 7559-81-1 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

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InventoryRef cosing-live-1000432023-05-23

CHLOROKOJIC ACID

Chlorokojic Acid is the organic compound that conforms to the formula:

CHLOROKOJIC ACID is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 7559-81-1

CAS 7559-81-1PubChem CID 82051

Chlorokojic acid

IUPAC name: 2-(chloromethyl)-5-hydroxypyran-4-one

Molecular formula: C6H5ClO3
Molecular weight: 160.55 g/mol
Exact mass: 159.9927217 Da
XLogP3: 0.4
Topological polar surface area: 46.5 Å²
Hydrogen-bond donors: 1
Hydrogen-bond acceptors: 3
Covalent units: 1
Defined stereocentres: 0

Also known as

2-(Chloromethyl)-5-hydroxy-4H-pyran-4-one4H-Pyran-4-one, 2-(chloromethyl)-5-hydroxy-NSC 10216NSC-10216CHLORO KOJIC ACIDNSC 298537NSC-298537AI3-02547

16 more reported names

2-CHLOROMETHYL-5-HYDROXY-4-PYRONE5-hydroxy-2-(chloromethyl)-4h-pyran-4-oneRefChem:575863CHLOROKOJIC ACID [INCI]815-637-7UB7QQW2D472-chloromethyl-5-hydroxy-pyran-4-one2-chloromethyl-5-hydroxy-4h-pyran-4-one(2-Chloromethyl)-5-hydroxy-4H-pyran-4-oneUNII-UB7QQW2D47chloro-kojic acidWSVIQCQIJLDTEK-UHFFFAOYSA-GLXC-03402EBC-6129832-(chloromethyl)-5-hydroxy-pyran-4-oneKSC-11-222-4

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External database identifiers

ChEMBL:CHEMBL506570
EPA DTXSID:DTXSID6064741
PubMed:21582022
PubMed:20591538

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Official European Commission record

CosIng substance ID: 100043
Entry status: Active
Published in the Official Journal: Yes
Recorded by the Commission: 2023-05-23

Open this entry in the official CosIng database

Fields as published by the European Commission. The link opens the entry itself, not a search for it.

Inventory details for CHLOROKOJIC ACID

INCI name

CHLOROKOJIC ACID

Description

Chlorokojic Acid is the organic compound that conforms to the formula:

Record provenance

Inventory reference: cosing-live-100043
Imported identity: CHLOROKOJIC ACID
Source update: 2023-05-23

European Commission CosIng source notes

Annex records for CHLOROKOJIC ACID

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Key data

CAS

7559-81-1

—

Restriction

—

Function

ANTI-SEBUM: Helping control sebum production.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#6227 · CHLOROKOJIC ACID

Ingredients with overlapping formulation functions

CARDIOSPERMUM HALICACABUM SEED EXTRACTANTI-SEBORRHEIC, ANTI-SEBUM, ANTIMICROBIAL, SKIN CONDITIONING

CARTHAMUS TINCTORIUS FLOWER/VITIS VINIFERA FRUIT/(CAMELIA SINENSIS/DIOSPYROS KA…ANTI-SEBUM, ANTIMICROBIAL, ANTIOXIDANT, SKIN CONDITIONING, SKIN PROTECTING

CASSYTHA FILIFORMIS POWDERANTI-SEBUM, ANTIOXIDANT, PRESERVATIVE, SKIN CONDITIONING, SKIN PROTECTING

CENTIPEDA CUNNINGHAMII LEAF/STEM EXTRACTANTI-SEBUM, ANTIOXIDANT, SKIN PROTECTING

CHROMOBACTERIUM VIOLACEUM EXTRACTANTIMICROBIAL; ANTI-SEBUM; COLORANT

CHRYSANTHEMUM LAVANDULIFOLIUM FLOWER EXTRACTANTIMICROBIAL; ANTIOXIDANT; ANTI-SEBUM; SKIN CONDITIONING - MISCELLANEOUS

CINNAMOMUM CASSIA BARK OILANTI-SEBUM, ANTIMICROBIAL, ANTIOXIDANT, ANTIPLAQUE, FLAVOURING, FRAGRANCE

CINNAMOMUM CASSIA BARK WATERANTI-SEBUM, ANTIMICROBIAL, ASTRINGENT

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How CHLOROKOJIC ACID appears in the CosIng inventory

The CosIng inventory lists CHLOROKOJIC ACID as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

CHLOROKOJIC ACID is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

CHLOROKOJIC ACID is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, CHLOROKOJIC ACID carries the following function designation(s):

ANTI-SEBUM

CAS 7559-81-1 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for CHLOROKOJIC ACID

This page reproduces the CosIng inventory entry for CHLOROKOJIC ACID from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research CHLOROKOJIC ACID and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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