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InventoryRef 9744603/10/2019

1,4-CYCLOHEXANEDICARBOXYLIC ACID

1,4-Cyclohexanedicarboxylic Acid is the organic acid that conforms to the formula

1,4-CYCLOHEXANEDICARBOXYLIC ACID is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 1076-97-7
CAS 1076-97-7PubChem CID 14106

1,4-Cyclohexanedicarboxylic acid

1,4-cyclohexanedicarboxylic acid is a dicarboxylic acid that is cyclohexane substituted by carboxy groups at positions 1 and 4. — ChEBI

IUPAC name
cyclohexane-1,4-dicarboxylic acid
Molecular formula
C8H12O4
Molecular weight
172.18 g/mol
Exact mass
172.07355886 Da
XLogP3
0.5
Topological polar surface area
74.6 Ų
Hydrogen-bond donors
2
Hydrogen-bond acceptors
4
Covalent units
1
Defined stereocentres
0

Also known as

Hexahydroterephthalic acid1,4-DicarboxycyclohexaneTerephthalic acid, hexahydro-(1S,4S)-CYCLOHEXANE-1,4-DICARBOXYLIC ACIDEINECS 214-068-613LBH83IU4PXGZQGDTEZPERC-UHFFFAOYSA-CHEBI:145052
16 more reported names
EC 214-068-61,4-CHDA-HPRefChem:4165741,4-BENZENEDICARBOXYLIC ACID, HEXAHYDRO-214-068-6679-605-2InChI=1/C8H12O4/c9-7(10)5-1-2-6(4-3-5)8(11)12/h5-6H,1-4H2,(H,9,10)(H,11,12)trans-1,4-Cyclohexanedicarboxylic acid619-82-9619-81-8cis-1,4-Cyclohexanedicarboxylic acidcis-Cyclohexane-1,4-dicarboxylic acidtrans-Cyclohexane-1,4-dicarboxylic acidcis-Hexahydroterephthalic acidtrans-1,4-Cyclohexanedicarboxybic acidtrans-Hexahydroterephthalic acid
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Evidence from additional scientific databases

EMBL-EBI ChEBI
Exact identifier matchCHEBI:145052

1,4-cyclohexanedicarboxylic acid

A dicarboxylic acid that is cyclohexane substituted by carboxy groups at positions 1 and 4.

Formula
C8H12O4
Average mass
172.180 g/mol
Monoisotopic mass
172.07356 Da
Formal charge
0
  • dicarboxylic acid — is a (CHEBI:35692)
  • dicarboxylic acid — is a (CHEBI:35692)
Additional curated names
cyclohexane-1,4-dicarboxylic acidhexahydroterephthalic acid
Cross-references from this source

Mapped by: Exact CAS cross-reference in the ChEBI compound record. Source updated: 2019-10-15. Retrieved: 2026-08-31. Open source record

NIH PubChem PUG-View
Exact identifier match14106

Attributed physical-property, hazard, environmental and use annotations.

  • Note: This chemical does not meet GHS hazard criteria for 55.8% (218 of 391) of all reports. Source: European Chemicals Agency (ECHA)
  • Signal: Warning Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H302 (12.3%): Harmful if swallowed [Warning Acute toxicity, oral]; H319 (44.2%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P264, P264+P265, P270, P280, P301+P317, P305+P351+P338, P330, P337+P317, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 391 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Reported as not meeting GHS hazard criteria per 218 of 391 reports by companies.; There are 4 notifications provided by 173 of 391 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H315 (60%): Causes skin irritation [Warning Skin corrosion/irritation]; H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H335 (16%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 25 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]; H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H335 (10%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 10 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
EMBL-EBI ChEBIExact match2026-08-31
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for 1,4-CYCLOHEXANEDICARBOXYLIC ACID

INCI name

1,4-CYCLOHEXANEDICARBOXYLIC ACID

Description

1,4-Cyclohexanedicarboxylic Acid is the organic acid that conforms to the formula

Record provenance

Inventory reference
97446
Imported identity
1,4-CYCLOHEXANEDICARBOXYLIC ACID
Source update
03/10/2019
European Commission CosIng source notes
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Key data

CAS
1076-97-7
EC
214-068-6
Restriction
—
Function
NOT REPORTED
No function currently reported.

Ingredients with overlapping formulation functions

1,2-BIS-(2-AMINOETHOXY)ETHANENOT REPORTED
1,3-BIS-(2,4-DIAMINOPHENOXY) PROPANE HCLNOT REPORTED
1,3-BIS-(ISOCYANATOMETHYL) CYCLOHEXANENOT REPORTED
1,6-HEXAMETHYLENE DIISOCYANATENOT REPORTED
2,3-EPOXYPROPYL COCODIMONIUM CHLORIDENOT REPORTED
2,3-EPOXYPROPYL LAURYLDIMONIUM CHLORIDENOT REPORTED
2,3-EPOXYPROPYLTRIMONIIUM CHLORIDENOT REPORTED
2-ACRYLAMIDO-2-METHYLPROPANE SULFONIC ACIDNOT REPORTED

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicalsPubChem PUG RESTEU Safety Gate cosmetic product alertsECHA CHEMUS EPA CompToxCosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortal

How 1,4-CYCLOHEXANEDICARBOXYLIC ACID appears in the CosIng inventory

The CosIng inventory lists 1,4-CYCLOHEXANEDICARBOXYLIC ACID as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

1,4-CYCLOHEXANEDICARBOXYLIC ACID is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

1,4-CYCLOHEXANEDICARBOXYLIC ACID is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, 1,4-CYCLOHEXANEDICARBOXYLIC ACID carries the following function designation(s):

CAS 1076-97-7 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.
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Source note for 1,4-CYCLOHEXANEDICARBOXYLIC ACID

This page reproduces the CosIng inventory entry for 1,4-CYCLOHEXANEDICARBOXYLIC ACID from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research 1,4-CYCLOHEXANEDICARBOXYLIC ACID and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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