CAS 1076-97-7PubChem CID 14106
1,4-Cyclohexanedicarboxylic acid
1,4-cyclohexanedicarboxylic acid is a dicarboxylic acid that is cyclohexane substituted by carboxy groups at positions 1 and 4. — ChEBI
- IUPAC name
- cyclohexane-1,4-dicarboxylic acid
- Molecular formula
- C8H12O4
- Molecular weight
- 172.18 g/mol
- Exact mass
- 172.07355886 Da
- XLogP3
- 0.5
- Topological polar surface area
- 74.6 Ų
- Hydrogen-bond donors
- 2
- Hydrogen-bond acceptors
- 4
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
Hexahydroterephthalic acid1,4-DicarboxycyclohexaneTerephthalic acid, hexahydro-(1S,4S)-CYCLOHEXANE-1,4-DICARBOXYLIC ACIDEINECS 214-068-613LBH83IU4PXGZQGDTEZPERC-UHFFFAOYSA-CHEBI:145052
16 more reported names
EC 214-068-61,4-CHDA-HPRefChem:4165741,4-BENZENEDICARBOXYLIC ACID, HEXAHYDRO-214-068-6679-605-2InChI=1/C8H12O4/c9-7(10)5-1-2-6(4-3-5)8(11)12/h5-6H,1-4H2,(H,9,10)(H,11,12)trans-1,4-Cyclohexanedicarboxylic acid619-82-9619-81-8cis-1,4-Cyclohexanedicarboxylic acidcis-Cyclohexane-1,4-dicarboxylic acidtrans-Cyclohexane-1,4-dicarboxylic acidcis-Hexahydroterephthalic acidtrans-1,4-Cyclohexanedicarboxybic acidtrans-Hexahydroterephthalic acid
External database identifiers
- ChEBI:CHEBI:145052
- ChEMBL:CHEMBL3187151
- EPA DTXSID:DTXSID001290604
- EPA DTXSID:DTXSID2038788
- EPA DTXSID:DTXSID901031536
- PubMed:22945794
- PubMed:21583309
- PubMed:21583153
- PubMed:21582692
- PubMed:21582053
- PubMed:21580265
- PubMed:21579917
- PubMed:21577703
- PubMed:21522256
- PubMed:21422616
- PubMed:21202471
- PubMed:20826823
Evidence from additional scientific databases
EMBL-EBI ChEBI
Exact identifier matchCHEBI:145052
1,4-cyclohexanedicarboxylic acid
A dicarboxylic acid that is cyclohexane substituted by carboxy groups at positions 1 and 4.
- Formula
- C8H12O4
- Average mass
- 172.180 g/mol
- Monoisotopic mass
- 172.07356 Da
- Formal charge
- 0
- dicarboxylic acid — is a (CHEBI:35692)
- dicarboxylic acid — is a (CHEBI:35692)
Additional curated names
cyclohexane-1,4-dicarboxylic acidhexahydroterephthalic acid
Mapped by: Exact CAS cross-reference in the ChEBI compound record. Source updated: 2019-10-15. Retrieved: 2026-08-31. Open source record
NIH PubChem PUG-View
Exact identifier match14106
Attributed physical-property, hazard, environmental and use annotations.
- Physical Description: Other Solid Source: EPA Chemical Data Reporting (CDR)
- Note: This chemical does not meet GHS hazard criteria for 55.8% (218 of 391) of all reports. Source: European Chemicals Agency (ECHA)
- Signal: Warning Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: H302 (12.3%): Harmful if swallowed [Warning Acute toxicity, oral]; H319 (44.2%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] Source: European Chemicals Agency (ECHA)
- Precautionary Statement Codes: P264, P264+P265, P270, P280, P301+P317, P305+P351+P338, P330, P337+P317, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: Aggregated GHS information provided per 391 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Reported as not meeting GHS hazard criteria per 218 of 391 reports by companies.; There are 4 notifications provided by 173 of 391 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: H315 (60%): Causes skin irritation [Warning Skin corrosion/irritation]; H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H335 (16%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] Source: European Chemicals Agency (ECHA)
- Precautionary Statement Codes: P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: Aggregated GHS information provided per 25 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]; H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H335 (10%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: Aggregated GHS information provided per 10 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- Consumer Uses: Not Known or Reasonably Ascertainable Source: EPA Chemical Data Reporting (CDR)
- Industry Uses: Monomers Source: EPA Chemical Data Reporting (CDR)
Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record
Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.
Additional source coverage and match status
| Source | Result | Checked |
|---|---|---|
| EMBL-EBI ChEBI | Exact match | 2026-08-31 |
| NIH PubChem PUG-View | Exact match | 2026-08-31 |
A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.