InventoryRef 9700325/04/2019

R-(ASPARTYL OLIGOPEPTIDE-162 HEXAPEPTIDE-40 ASPARTYL RH-POLYPEPTIDE-114)/R- (ASPARTYL OLIGOPEPTIDE-162 ASPARTYL RH-POLYPEPTIDE-115)/R-( ASPARTYL OLIGOPEPTIDE-162 ASPARTYL RH-POLYPEPTIDE-48)

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Regulatory evidence by market

This matrix separates verified ingredient rules from sources that are mapped but not yet imported. No imported rule does not mean the ingredient is permitted.

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Market	Evidence status	Records	Source language
European Union	Evidence linked Prohibited entry found Open this evidence	1	English and EU languages
Great Britain	Source mapped Official source mapped; ingredient rule not imported	0	English
Canada	Source mapped Official source mapped; ingredient rule not imported	0	English and French
New Zealand	Source mapped Official source mapped; ingredient rule not imported	0	English
ASEAN	Source mapped Official source mapped; ingredient rule not imported	0	English and national languages
China	Source mapped Official source mapped; ingredient rule not imported	0	Chinese with selected English material
Japan	Source mapped Official source mapped; ingredient rule not imported	0	Japanese; official English translation available
South Korea	Source mapped Official source mapped; ingredient rule not imported	0	Korean with some English names
United States	Source mapped Official source mapped; ingredient rule not imported	0	English
Australia	Source mapped Official source mapped; ingredient rule not imported	0	English
Brazil	Source mapped Official source mapped; ingredient rule not imported	0	Portuguese with INCI crosswalks
India	Source mapped Official source mapped; ingredient rule not imported	0	English and Hindi
Saudi Arabia	Source mapped Official source mapped; ingredient rule not imported	0	Arabic and English

What the official INCI name states

The official label is a composite INCI name with 3 named source-material segments. Each segment must be reconciled with the supplier specification.

Identity type from wording: composite
Named source segments: 3

Review parsed source-name segments

R-ASPARTYL OLIGOPEPTIDE-162 HEXAPEPTIDE-40 ASPARTYL RH-POLYPEPTIDE-114
R- ASPARTYL OLIGOPEPTIDE-162 ASPARTYL RH-POLYPEPTIDE-115
R- ASPARTYL OLIGOPEPTIDE-162 ASPARTYL RH-POLYPEPTIDE-48

This structure is derived only from the official label wording. It does not establish composition, concentration, chemical equivalence, safety or regulatory permission.

Inventory details for R-(ASPARTYL OLIGOPEPTIDE-162 HEXAPEPTIDE-40 ASPARTYL RH-POLYPEPTIDE-114)/R- (ASPARTYL OLIGOPEPTIDE-162 ASPARTYL RH-POLYPEPTIDE-115)/R-( ASPARTYL OLIGOPEPTIDE-162 ASPARTYL RH-POLYPEPTIDE-48)

INCI name

R-(ASPARTYL OLIGOPEPTIDE-162 HEXAPEPTIDE-40 ASPARTYL RH-POLYPEPTIDE-114)/R- (ASPARTYL OLIGOPEPTIDE-162 ASPARTYL RH-POLYPEPTIDE-115)/R-( ASPARTYL OLIGOPEPTIDE-162 ASPARTYL RH-POLYPEPTIDE-48)

Description

r-(Aspartyl Oligopeptide-162 Hexapeptide-40 Aspartyl rh-Polypeptide-114)/r-(Aspartyl Oligopeptide-162 Aspartyl rh-Polypeptide-115)/r-( Aspartyl Oligopeptide-162 Aspartyl rh-Polypeptide-48) is the heterotrimeric peptide assembled by the combination of three recombinant fusion peptides: r-(Aspartyl Oligopeptide-162 Hexapeptide-40 Aspartyl rh-Polypeptide-114), r-(Aspartyl Oligopeptide-162 Aspartyl rh-Polypeptide-115), and r-(Aspartyl Oligopeptide-162 Aspartyl rh-Polypeptide-48). The three chains may have inter-chain and/or intra-chain disulfide bonds.

Record provenance

Inventory reference: 97003
Imported identity: R-(ASPARTYL OLIGOPEPTIDE-162 HEXAPEPTIDE-40 ASPARTYL RH-POLYPEPTIDE-114)/R- (ASPARTYL OLIGOPEPTIDE-162 ASPARTYL RH-POLYPEPTIDE-115)/R-( ASPARTYL OLIGOPEPTIDE-162 ASPARTYL RH-POLYPEPTIDE-48)
Source update: 25/04/2019

European Commission CosIng source notes

Annex records for R-(ASPARTYL OLIGOPEPTIDE-162 HEXAPEPTIDE-40 ASPARTYL RH-POLYPEPTIDE-114)/R- (ASPARTYL OLIGOPEPTIDE-162 ASPARTYL RH-POLYPEPTIDE-115)/R-( ASPARTYL OLIGOPEPTIDE-162 ASPARTYL RH-POLYPEPTIDE-48)

Annex II Restriction reference

Entry 416

Cells, tissues or products of human origin

Key data

CAS

—

The CosIng inventory records no CAS number for this ingredient. That is the absence of an identifier in the source, not a finding about the substance.

—

Restriction

II/416

Function

NOT REPORTED: No function currently reported.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#23951 · R-(ASPARTYL OLIGOPEPTIDE-162 HEXAPEPTIDE-40 ASPARTYL rh-POLYPEPTIDE-114)/R- (ASPARTYL OLIGOPEPTIDE-162 ASPARTYL rh-POLYPEPTIDE-115)/R-( ASPARTYL OLIGOPEPTIDE-162 ASPARTYL rh-POLYPEPTIDE-48)

Ingredients with overlapping formulation functions

PYRUS MALUS PEEL WAXNOT REPORTED

R-(ASPARTYL OLIGOPEPTIDE-162 ASPARTYL RH-POLYPEPTIDE-115)NOT REPORTED

R-(ASPARTYL OLIGOPEPTIDE-162 ASPARTYL RH-POLYPEPTIDE-48)NOT REPORTED

R-(ASPARTYL OLIGOPEPTIDE-162 HEXAPEPTIDE-40 ASPARTYL RH-POLYPEPTIDE-114)NOT REPORTED

R-(SH/S-MOUSE POLYPEPTIDE-1 SH-POLYPEPTIDE-95)NOT REPORTED

R-(SH/S-MOUSE POLYPEPTIDE-2 SH-POLYPEPTIDE-118)NOT REPORTED

R-ESCHERICHIA COLI THIOREDOXIN-1NOT REPORTED

R-MUSSEL POLYPEPTIDE-2NOT REPORTED

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How R-(ASPARTYL OLIGOPEPTIDE-162 HEXAPEPTIDE-40 ASPARTYL RH-POLYPEPTIDE-114)/R- (ASPARTYL OLIGOPEPTIDE-162 ASPARTYL RH-POLYPEPTIDE-115)/R-( ASPARTYL OLIGOPEPTIDE-162 ASPARTYL RH-POLYPEPTIDE-48) appears in the CosIng inventory

The CosIng inventory lists R-(ASPARTYL OLIGOPEPTIDE-162 HEXAPEPTIDE-40 ASPARTYL RH-POLYPEPTIDE-114)/R- (ASPARTYL OLIGOPEPTIDE-162 ASPARTYL RH-POLYPEPTIDE-115)/R-( ASPARTYL OLIGOPEPTIDE-162 ASPARTYL RH-POLYPEPTIDE-48) as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

R-(ASPARTYL OLIGOPEPTIDE-162 HEXAPEPTIDE-40 ASPARTYL RH-POLYPEPTIDE-114)/R- (ASPARTYL OLIGOPEPTIDE-162 ASPARTYL RH-POLYPEPTIDE-115)/R-( ASPARTYL OLIGOPEPTIDE-162 ASPARTYL RH-POLYPEPTIDE-48) is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

R-(ASPARTYL OLIGOPEPTIDE-162 HEXAPEPTIDE-40 ASPARTYL RH-POLYPEPTIDE-114)/R- (ASPARTYL OLIGOPEPTIDE-162 ASPARTYL RH-POLYPEPTIDE-115)/R-( ASPARTYL OLIGOPEPTIDE-162 ASPARTYL RH-POLYPEPTIDE-48) appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for R-(ASPARTYL OLIGOPEPTIDE-162 HEXAPEPTIDE-40 ASPARTYL RH-POLYPEPTIDE-114)/R- (ASPARTYL OLIGOPEPTIDE-162 ASPARTYL RH-POLYPEPTIDE-115)/R-( ASPARTYL OLIGOPEPTIDE-162 ASPARTYL RH-POLYPEPTIDE-48) reads: "II/416". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, R-(ASPARTYL OLIGOPEPTIDE-162 HEXAPEPTIDE-40 ASPARTYL RH-POLYPEPTIDE-114)/R- (ASPARTYL OLIGOPEPTIDE-162 ASPARTYL RH-POLYPEPTIDE-115)/R-( ASPARTYL OLIGOPEPTIDE-162 ASPARTYL RH-POLYPEPTIDE-48) carries the following function designation(s):

NOT REPORTED

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Source note for R-(ASPARTYL OLIGOPEPTIDE-162 HEXAPEPTIDE-40 ASPARTYL RH-POLYPEPTIDE-114)/R- (ASPARTYL OLIGOPEPTIDE-162 ASPARTYL RH-POLYPEPTIDE-115)/R-( ASPARTYL OLIGOPEPTIDE-162 ASPARTYL RH-POLYPEPTIDE-48)

This page combines the CosIng inventory entry for R-(ASPARTYL OLIGOPEPTIDE-162 HEXAPEPTIDE-40 ASPARTYL RH-POLYPEPTIDE-114)/R- (ASPARTYL OLIGOPEPTIDE-162 ASPARTYL RH-POLYPEPTIDE-115)/R-( ASPARTYL OLIGOPEPTIDE-162 ASPARTYL RH-POLYPEPTIDE-48) with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research R-(ASPARTYL OLIGOPEPTIDE-162 HEXAPEPTIDE-40 ASPARTYL RH-POLYPEPTIDE-114)/R- (ASPARTYL OLIGOPEPTIDE-162 ASPARTYL RH-POLYPEPTIDE-115)/R-( ASPARTYL OLIGOPEPTIDE-162 ASPARTYL RH-POLYPEPTIDE-48) and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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