InventoryRef 9630226/04/2019

NICOTIANA BENTHAMIANA R-(S-CLOSTRIDIUM BOTULINUM POLYPEPTIDE-1 S-SPIDER OLIGOPEPTIDE-1 SH-OLIGOPEPTIDE-1)

NICOTIANA BENTHAMIANA R-(S-CLOSTRIDIUM BOTULINUM POLYPEPTIDE-1 S-SPIDER OLIGOPEPTIDE-1 SH-OLIGOPEPTIDE-1) is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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What the official INCI name states

The official label identifies a peptide- or protein-related cosmetic material.

Identity type from wording: peptide_or_protein

This structure is derived only from the official label wording. It does not establish composition, concentration, chemical equivalence, safety or regulatory permission.

Inventory details for NICOTIANA BENTHAMIANA R-(S-CLOSTRIDIUM BOTULINUM POLYPEPTIDE-1 S-SPIDER OLIGOPEPTIDE-1 SH-OLIGOPEPTIDE-1)

INCI name

NICOTIANA BENTHAMIANA R-(S-CLOSTRIDIUM BOTULINUM POLYPEPTIDE-1 S-SPIDER OLIGOPEPTIDE-1 SH-OLIGOPEPTIDE-1)

Description

Nicotiana Benthamiana r-(s-Clostridium Botulinum Polypeptide-1 s-Spider Oligopeptide-1 sh-Oligopeptide-1) is a single chain recombinant protein produced by Nicotiana benthamiana after using either a transient expression system or transgenesis (stable insertion of a copy of the synthetic gene into its DNA). The starting gene is synthesized by the fusion of the genes from s-Clostridium Botulinum Polypeptide-1, s-Spider Oligopeptide-1, and sh-Oligopeptide-1. The peptide contains a maximum of 548 amino acids which may contain disulfide bonds and/or glycosylation. The fusion peptide consists of the proper sequence of the 20 standard amino acids.

Record provenance

Inventory reference: 96302
Imported identity: NICOTIANA BENTHAMIANA R-(S-CLOSTRIDIUM BOTULINUM POLYPEPTIDE-1 S-SPIDER OLIGOPEPTIDE-1 SH-OLIGOPEPTIDE-1)
Source update: 26/04/2019

European Commission CosIng source notes

Annex records for NICOTIANA BENTHAMIANA R-(S-CLOSTRIDIUM BOTULINUM POLYPEPTIDE-1 S-SPIDER OLIGOPEPTIDE-1 SH-OLIGOPEPTIDE-1)

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Search the annex database for entries matching NICOTIANA BENTHAMIANA R-(S-CLOSTRIDIUM BOTULINUM POLYPEPTIDE-1 S-SPIDER OLIGOPEPTIDE-1 SH-OLIGOPEPTIDE-1) or related substances.

Key data

CAS

—

The CosIng inventory records no CAS number for this ingredient. That is the absence of an identifier in the source, not a finding about the substance.

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Restriction

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Function

SKIN CONDITIONING: Maintaining the skin in good condition.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#17409 · NICOTIANA BENTHAMIANA R-(S-CLOSTRIDIUM BOTULINUM POLYPEPTIDE-1 S-SPIDER OLIGOPEPTIDE-1 sh-OLIGOPEPTIDE-1)

Other ingredients from the same source

Nicotiana benthamiana

24 other ingredients in this inventory name the same organism. Sharing a source is not sharing an identity: a leaf extract, a seed oil and a ferment are different materials with different specifications.

and 12 more

Ingredients with overlapping formulation functions

NICOTIANA BENTHAMIANA HEXAPEPTIDE-40 SH-POLYPEPTIDE-2HAIR CONDITIONING, SKIN CONDITIONING

NICOTIANA BENTHAMIANA HEXAPEPTIDE-40 SH-POLYPEPTIDE-5SKIN CONDITIONING

NICOTIANA BENTHAMIANA HEXAPEPTIDE-40 SH-POLYPEPTIDE-6SKIN CONDITIONING

NICOTIANA BENTHAMIANA HEXAPEPTIDE-40 SH-POLYPEPTIDE-76SKIN CONDITIONING

NICOTIANA BENTHAMIANA SH-POLIPEDTIDE-45SKIN CONDITIONING

NICOTIANA BENTHAMIANA SH-POLYPEDTIDE-7SKIN CONDITIONING

NICOTIANA BENTHAMIANA SH-POLYPEPTIDE-15 HEXAPEPTIDE-40SKIN CONDITIONING

NICOTIANA SYLVESTRIS LEAF CELL CULTURESKIN CONDITIONING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How NICOTIANA BENTHAMIANA R-(S-CLOSTRIDIUM BOTULINUM POLYPEPTIDE-1 S-SPIDER OLIGOPEPTIDE-1 SH-OLIGOPEPTIDE-1) appears in the CosIng inventory

The CosIng inventory lists NICOTIANA BENTHAMIANA R-(S-CLOSTRIDIUM BOTULINUM POLYPEPTIDE-1 S-SPIDER OLIGOPEPTIDE-1 SH-OLIGOPEPTIDE-1) as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

NICOTIANA BENTHAMIANA R-(S-CLOSTRIDIUM BOTULINUM POLYPEPTIDE-1 S-SPIDER OLIGOPEPTIDE-1 SH-OLIGOPEPTIDE-1) is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

NICOTIANA BENTHAMIANA R-(S-CLOSTRIDIUM BOTULINUM POLYPEPTIDE-1 S-SPIDER OLIGOPEPTIDE-1 SH-OLIGOPEPTIDE-1) is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, NICOTIANA BENTHAMIANA R-(S-CLOSTRIDIUM BOTULINUM POLYPEPTIDE-1 S-SPIDER OLIGOPEPTIDE-1 SH-OLIGOPEPTIDE-1) carries the following function designation(s):

SKIN CONDITIONING

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Source note for NICOTIANA BENTHAMIANA R-(S-CLOSTRIDIUM BOTULINUM POLYPEPTIDE-1 S-SPIDER OLIGOPEPTIDE-1 SH-OLIGOPEPTIDE-1)

This page reproduces the CosIng inventory entry for NICOTIANA BENTHAMIANA R-(S-CLOSTRIDIUM BOTULINUM POLYPEPTIDE-1 S-SPIDER OLIGOPEPTIDE-1 SH-OLIGOPEPTIDE-1) from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research NICOTIANA BENTHAMIANA R-(S-CLOSTRIDIUM BOTULINUM POLYPEPTIDE-1 S-SPIDER OLIGOPEPTIDE-1 SH-OLIGOPEPTIDE-1) and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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