Skip to main content
CosIng Checker
CosIng Checker
EU cosmetic ingredients, restrictions and safety
Login
InventoryRef 9574027/04/2018

ISOSORBIDE

Dianhydroglucitol,Dianhydrosorbitol,D-Glucitol, 1,4:3,6-dianhydro-

ISOSORBIDE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

INCI CheckerCompare all markets Search similar

Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

Markets and their official sourcesSearch every market for this name

Chemical identity and properties

PubChem 2D chemical structure for CAS 652-67-5
CAS 652-67-5PubChem CID 12597

Isosorbide

Isosorbide is an organic molecular entity. — ChEBI

IUPAC name
(3S,3aR,6R,6aR)-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-3,6-diol
Molecular formula
C6H10O4
Molecular weight
146.14 g/mol
Exact mass
146.05790880 Da
XLogP3
-1.4
Topological polar surface area
58.9 Ų
Hydrogen-bond donors
2
Hydrogen-bond acceptors
4
Covalent units
1
Defined stereocentres
4

Also known as

IsobideDevicoran1,4:3,6-Dianhydro-D-glucitolHydronolIsmotic(3R,3aR,6S,6aR)-hexahydrofuro[3,2-b]furan-3,6-diol(+)-D-IsosorbideD-Glucitol, 1,4:3,6-dianhydro-
16 more reported names
1,4:3,6-Dianhydro-D-sorbitol1,4:3,6-DianhydrosorbitolNSC-40725Glucitol, 1,4:3,6-dianhydro-, D-WXR179L51S(3R,3aR,6S,6aR)-hexahydrofuro(3,2-b)furan-3,6-diolRefChem:55420GlyTouCan:G82967ZA211-492-3SorbidVascardin dinitrate1,4-DianhydrosorbitolDianhydro-D-glucitolIsosorbidaD-Isosorbide;Dianhydro-D-glucitolSorbitol, 1,4:3,6-dianhydro-
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for ISOSORBIDE

INCI name

ISOSORBIDE

Description

Dianhydroglucitol,Dianhydrosorbitol,D-Glucitol, 1,4:3,6-dianhydro-

Record provenance

Inventory reference
95740
Imported identity
ISOSORBIDE
Source update
27/04/2018
European Commission CosIng source notes
Browse

Browse EU annexes

Explore Annex II–VI to see which substances are prohibited, restricted or permitted under specific conditions.

Search

Search annex entries

Search the annex database for entries matching ISOSORBIDE or related substances.

Key data

CAS
652-67-5
EC
211-492-3 (I)
Restriction
—
Function
HUMECTANT
Retaining and/or preserving the moisture in a product during use.
SKIN CONDITIONING
Maintaining the skin in good condition.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#13901 · ISOSORBIDE

Ingredients with overlapping formulation functions

ISOMALTHUMECTANT
ISOMALTOOLIGOSACCHARIDEHUMECTANT; SKIN PROTECTING
ISOPOLYGLYCERYL-3 DIMETHICONECLEANSING, HAIR CONDITIONING, HUMECTANT, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SURFACTA…
ISOPROPYL PCAHUMECTANT
ISOSORBIDE DISUNFLOWERSEEDATEHUMECTANT, PLASTICISER, SKIN CONDITIONING
ISOSTEARYL PCAHUMECTANT, SKIN CONDITIONING - EMOLLIENT
ISOTRIACONTANEANTIOXIDANT, ASTRINGENT, HAIR CONDITIONING, HUMECTANT, SKIN CONDITIONING - EMOLLIENT, SKIN CONDITIO…
IXERIDIUM DENTATUM EXTRACTHUMECTANT, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SKIN PROTECTING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicalsPubChem PUG RESTEU Safety Gate cosmetic product alertsECHA CHEMUS EPA CompToxCosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortal

How ISOSORBIDE appears in the CosIng inventory

The CosIng inventory lists ISOSORBIDE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

ISOSORBIDE is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

ISOSORBIDE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, ISOSORBIDE carries the following function designation(s):

CAS 652-67-5 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.
View CAS records

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.
Open INCI Checker

Source note for ISOSORBIDE

This page reproduces the CosIng inventory entry for ISOSORBIDE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research ISOSORBIDE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

View sourcesView updates

Tools & next steps

Check your formula

Scan a full INCI list to detect ISOSORBIDE and any linked EU annex restrictions or allergen flags.

INCI Checker

Search similar ingredients

Find other inventory ingredients and annex entries related to ISOSORBIDE, its identifiers or nearby name variants.

Search