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InventoryRef 9545230/04/2018

METHYL PERFLUORO BUTYL/ISOBUTYL ETHER

Butane, 1,1,1,2,2,3,3,4,4-nonafluoro-4-methoxy-,Propane, 2-(difluoromethoxymethyl)-1,1,1,2,3,3,3-heptafluoro-

METHYL PERFLUORO BUTYL/ISOBUTYL ETHER is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 163702-07-6

CAS 163702-07-6PubChem CID 164514

Methyl perfluorobutyl ether

IUPAC name: 1,1,1,2,2,3,3,4,4-nonafluoro-4-methoxybutane

Molecular formula: C5H3F9O
Molecular weight: 250.06 g/mol
Exact mass: 250.00401817 Da
XLogP3: 3.3
Topological polar surface area: 9.2 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 10
Covalent units: 1
Defined stereocentres: 0

Also known as

Methyl Nonafluorobutyl EtherButane, 1,1,1,2,2,3,3,4,4-nonafluoro-4-methoxy-Nonafluorobutyl methyl ether(perfluorobutoxy)methaneH637A50B7U1-methoxynonafluorobutaneMETHYL 1,1,2,2,3,3,4,4,4-NONAFLUOROBUTYL ETHERRefChem:818025

16 more reported names

METHYL PERFLUOROBUTYL ETHER [INCI]Butane, 1,1,1,2,2,3,3,4,4nonafluoro4methoxyFractionated and Column Treated HFE7100 from Methylbutyrate ECF. F12429 (Intermediate)605-339-3829-015-8METHOXYPERFLUOROBUTANEPerfluorobutyl Methyl EtherUNII-H637A50B7U1,1,1,2,2,3,3,4,4-nonafluoro-4-methoxy-butaneCF3CF2CF2CF2OCH3C4F9OCH3FD2030Novec(R) HFE-7100 Engineered FluidHFE-449s1 (7100)Novec(R) HFE-7100DL Engineered FluidAS-48915

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External database identifiers

ChEMBL:CHEMBL500823
EPA DTXSID:DTXSID4073120
PubMed:22592967
PubMed:18851453
PubMed:15921925

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 163702-08-7

CAS 163702-08-7PubChem CID 4156734

Methyl perfluoroisobutyl ether

IUPAC name: 2-[difluoro(methoxy)methyl]-1,1,1,2,3,3,3-heptafluoropropane

Molecular formula: C5H3F9O
Molecular weight: 250.06 g/mol
Exact mass: 250.00401817 Da
XLogP3: 3.3
Topological polar surface area: 9.2 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 10
Covalent units: 1
Defined stereocentres: 0

Also known as

perfluoroisobutyl methyl etherPropane, 2-(difluoromethoxymethyl)-1,1,1,2,3,3,3-heptafluoro-HI89P35AAXmethyl nonafluoroisobutyl etherUNII-HI89P35AAX1,1,2,3,3,3-HEXAFLUORO-1-METHOXY-2-(TRIFLUOROMETHYL)PROPANE2-(difluoromethoxymethyl)-1,1,1,2,3,3,3-heptafluoropropanemethylperfluorobutylether

12 more reported names

RefChem:157993METHYL PERFLUOROISOBUTYL ETHER [INCI]VF45 (TM) HFEBased Cleaning Fluid, VOL0570APropane, 2(difluoromethoxymethyl)1,1,1,2,3,3,3heptafluoro422-270-2605-340-91,1,1,2,3,3-hexafluoro-3-methoxy-2-(trifluoromethyl)propane2-[Difluoro(methoxy)methyl]-1,1,1,2,3,3,3-heptafluoro-propane2-(difluoro(methoxy)methyl)-1,1,1,2,3,3,3-heptafluoropropane(CF3)2CFCF2OCH3methyl perfluoroisobutanyl etherDB-352148

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External database identifiers

ChEMBL:CHEMBL477673
EPA DTXSID:DTXSID5042326

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

What the official INCI name states

The official label is a composite INCI name with 2 named source-material segments. Each segment must be reconciled with the supplier specification.

Identity type from wording: composite
Named source segments: 2

Review parsed source-name segments

METHYL PERFLUORO BUTYL
ISOBUTYL ETHER

This structure is derived only from the official label wording. It does not establish composition, concentration, chemical equivalence, safety or regulatory permission.

Inventory details for METHYL PERFLUORO BUTYL/ISOBUTYL ETHER

INCI name

METHYL PERFLUORO BUTYL/ISOBUTYL ETHER

Description

Butane, 1,1,1,2,2,3,3,4,4-nonafluoro-4-methoxy-,Propane, 2-(difluoromethoxymethyl)-1,1,1,2,3,3,3-heptafluoro-

Record provenance

Inventory reference: 95452
Imported identity: METHYL PERFLUORO BUTYL/ISOBUTYL ETHER
Source update: 30/04/2018

European Commission CosIng source notes

Annex records for METHYL PERFLUORO BUTYL/ISOBUTYL ETHER

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Key data

CAS

163702-07-6,163702-08-7

Restriction

—

Function

SOLVENT: Dissolving other components of cosmetics. Solvents are usually liquids (aqueous and nonaqueous).

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#16561 · METHYL PERFLUORO BUTYL/ISOBUTYL ETHER

Records sharing a CAS or EC identity

BANKSIA SERRATA SEED OIL COPAIFERA CORIACEA RESIN OIL COPAIFERA LANGSDORFFII RESIN OIL COPAIFERA RETICULATA RESIN OIL CYCLOHEXYL TOLUATE EREMOPHILA LONGIFOLIA LEAF EXTRACT HC BLUE NO. 18 LAURYL ASPARTIC ACID

Ingredients with overlapping formulation functions

METHYL ISOBUTYL GLYCEROL FORMALSOLVENT

METHYL LACTATEFLAVOURING, PERFUMING, SOLVENT

METHYL LAURATE/MYRISTATESKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SOLVENT, SURFACTANT - CLEANSING

METHYL OLEATE/PALMITATE/LINOLEATE/STEARATESKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SOLVENT, SURFACTANT - CLEANSING

METHYL PERFLUOROBUTYL ETHERSOLVENT, VISCOSITY CONTROLLING

METHYL PERFLUOROISOBUTYL ETHERSOLVENT, VISCOSITY CONTROLLING

METHYL PYRROLIDONESOLVENT

METHYL SUNFLOWERSEEDATESKIN CONDITIONING - EMOLLIENT, SOLVENT

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How METHYL PERFLUORO BUTYL/ISOBUTYL ETHER appears in the CosIng inventory

The CosIng inventory lists METHYL PERFLUORO BUTYL/ISOBUTYL ETHER as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

METHYL PERFLUORO BUTYL/ISOBUTYL ETHER is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

METHYL PERFLUORO BUTYL/ISOBUTYL ETHER is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, METHYL PERFLUORO BUTYL/ISOBUTYL ETHER carries the following function designation(s):

SOLVENT

CAS 163702-07-6,163702-08-7 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for METHYL PERFLUORO BUTYL/ISOBUTYL ETHER

This page reproduces the CosIng inventory entry for METHYL PERFLUORO BUTYL/ISOBUTYL ETHER from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research METHYL PERFLUORO BUTYL/ISOBUTYL ETHER and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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