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CAS 163702-07-6 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

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InventoryRef 5811315/10/2010

METHYL PERFLUOROBUTYL ETHER

1,1,1,2,3,3,3,4,4-nonafluoro-4-methoxybutane

METHYL PERFLUOROBUTYL ETHER is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 163702-07-6

CAS 163702-07-6PubChem CID 164514

Methyl perfluorobutyl ether

IUPAC name: 1,1,1,2,2,3,3,4,4-nonafluoro-4-methoxybutane

Molecular formula: C5H3F9O
Molecular weight: 250.06 g/mol
Exact mass: 250.00401817 Da
XLogP3: 3.3
Topological polar surface area: 9.2 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 10
Covalent units: 1
Defined stereocentres: 0

Also known as

Methyl Nonafluorobutyl EtherButane, 1,1,1,2,2,3,3,4,4-nonafluoro-4-methoxy-Nonafluorobutyl methyl ether(perfluorobutoxy)methaneH637A50B7U1-methoxynonafluorobutaneMETHYL 1,1,2,2,3,3,4,4,4-NONAFLUOROBUTYL ETHERRefChem:818025

16 more reported names

METHYL PERFLUOROBUTYL ETHER [INCI]Butane, 1,1,1,2,2,3,3,4,4nonafluoro4methoxyFractionated and Column Treated HFE7100 from Methylbutyrate ECF. F12429 (Intermediate)605-339-3829-015-8METHOXYPERFLUOROBUTANEPerfluorobutyl Methyl EtherUNII-H637A50B7U1,1,1,2,2,3,3,4,4-nonafluoro-4-methoxy-butaneCF3CF2CF2CF2OCH3C4F9OCH3FD2030Novec(R) HFE-7100 Engineered FluidHFE-449s1 (7100)Novec(R) HFE-7100DL Engineered FluidAS-48915

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEMBL:CHEMBL500823
EPA DTXSID:DTXSID4073120
PubMed:22592967
PubMed:18851453
PubMed:15921925

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for METHYL PERFLUOROBUTYL ETHER

INCI name

METHYL PERFLUOROBUTYL ETHER

Description

1,1,1,2,3,3,3,4,4-nonafluoro-4-methoxybutane

Record provenance

Inventory reference: 58113
Imported identity: METHYL PERFLUOROBUTYL ETHER
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for METHYL PERFLUOROBUTYL ETHER

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Key data

CAS

163702-07-6

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Restriction

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Function

SOLVENT: Dissolving other components of cosmetics. Solvents are usually liquids (aqueous and nonaqueous).
VISCOSITY CONTROLLING: Increasing or decreasing the viscosity (thickness) of cosmetics.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#16562 · METHYL PERFLUOROBUTYL ETHER

Ingredients with overlapping formulation functions

METHYL LACTATEFLAVOURING, PERFUMING, SOLVENT

METHYL LAURATE/MYRISTATESKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SOLVENT, SURFACTANT - CLEANSING

METHYL OLEATE/PALMITATE/LINOLEATE/STEARATESKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SOLVENT, SURFACTANT - CLEANSING

METHYL PERFLUORO BUTYL/ISOBUTYL ETHERSOLVENT

METHYL PERFLUOROISOBUTYL ETHERSOLVENT, VISCOSITY CONTROLLING

METHYL PYRROLIDONESOLVENT

METHYL SUNFLOWERSEEDATESKIN CONDITIONING - EMOLLIENT, SOLVENT

METHYL TRIMETHICONEHAIR CONDITIONING, SKIN CONDITIONING, SOLVENT

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How METHYL PERFLUOROBUTYL ETHER appears in the CosIng inventory

The CosIng inventory lists METHYL PERFLUOROBUTYL ETHER as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

METHYL PERFLUOROBUTYL ETHER is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

METHYL PERFLUOROBUTYL ETHER is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, METHYL PERFLUOROBUTYL ETHER carries the following function designation(s):

CAS 163702-07-6 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for METHYL PERFLUOROBUTYL ETHER

This page reproduces the CosIng inventory entry for METHYL PERFLUOROBUTYL ETHER from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research METHYL PERFLUOROBUTYL ETHER and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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