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CAS 4246-51-9 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

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InventoryRef 9545013/12/2017

BIS-AMINOPROPYL DIGLYCOL

1-Propanamine, 3,3'-[oxybis(2,1-ethanediyloxy)] bis-

BIS-AMINOPROPYL DIGLYCOL is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 4246-51-9

CAS 4246-51-9PubChem CID 20239

Diethylene glycol bis(3-aminopropyl) ether

IUPAC name: 3-[2-[2-(3-aminopropoxy)ethoxy]ethoxy]propan-1-amine

Molecular formula: C10H24N2O3
Molecular weight: 220.31 g/mol
Exact mass: 220.17869263 Da
XLogP3: -1.4
Topological polar surface area: 79.7 Å²
Hydrogen-bond donors: 2
Hydrogen-bond acceptors: 5
Covalent units: 1
Defined stereocentres: 0

Also known as

4,7,10-Trioxa-1,13-tridecanediamine4,7,10-trioxatridecane-1,13-diamineEINECS 224-207-2Di(3-aminopropyl) ether of diethylene glycolBRN 1760709DIETHYLENE GLYCOL, DI(3-AMINOPROPYL) ETHERO,O'-Bis(3-aminopropyl)diethylene glycol3,3'-Oxybis(ethyleneoxy)bis(propylamine)

16 more reported names

DPA-DEG95W232H4RT1-Propanamine, 3,3'-(oxybis(2,1-ethanediyloxy))bis-1-Propanamine, 3,3'-[oxybis(2,1-ethanediyloxy)]bis-Q 19262ANCAMINE 19221,13-diamino-4,7,10-trioxatridecane3,3'-(Oxybis(2,1-ethanediyloxy))bis-1-propanamine3,3'-[Oxybis(2,1-ethanediyloxy)]bis-1-propanamine3,3'-[OXYBIS(ETHANE-2,1-DIYLOXY)]DIPROPAN-1-AMINEEC 224-207-2Bis[2-(3-aminopropoxy)ethyl] EtherBIS(2-(3-AMINOPROPOXY)ETHYL) ETHER4,7,10-TRIOXA-1,13-TRIDECANAMINEPROPYLAMINE, 3,3'-(OXYBIS(ETHYLENEOXY))BIS-3,3'-(OXYBIS(ETHANE-2,1-DIYLOXY))DIPROPAN-1-AMINE

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEMBL:CHEMBL3187499
EPA DTXSID:DTXSID6044565
PubMed:20799032
PubMed:19140161
PubMed:16208680
PubMed:12236790
PubMed:11336310

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for BIS-AMINOPROPYL DIGLYCOL

INCI name

BIS-AMINOPROPYL DIGLYCOL

Description

1-Propanamine, 3,3'-[oxybis(2,1-ethanediyloxy)] bis-

Record provenance

Inventory reference: 95450
Imported identity: BIS-AMINOPROPYL DIGLYCOL
Source update: 13/12/2017

European Commission CosIng source notes

Annex records for BIS-AMINOPROPYL DIGLYCOL

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Key data

CAS

4246-51-9

—

Restriction

—

Function

HAIR CONDITIONING: Enhancing the appearance and feel of hair. Leaving the hair easy to comb, supple, soft and shiny and/or imparting volume, lightness, gloss, texture, etc.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#3514 · BIS-AMINOPROPYL DIGLYCOL

Ingredients with overlapping formulation functions

BIS-(POLYGLYCERYL-3 OXYPHENYLPROPYL) DIMETHICONEHAIR CONDITIONING, SKIN CONDITIONING

BIS-(POLYGLYCERYL-7 OXYPHENYLPROPYL) DIMETHICONEHAIR CONDITIONING, SKIN CONDITIONING

BIS-(PPG-7 UNDECENETH-21) DIMETHICONESURFACTANT - EMULSIFYING; HAIR CONDITIONING; SKIN CONDITIONING - MISCELLANEOUS

BIS-4-PCA DIMETHICONEHAIR CONDITIONING

BIS-AMINOPROPYL DIGLYCOL DIMALEATEHAIR CONDITIONING, HAIR WAVING OR STRAIGHTENING, SKIN CONDITIONING

BIS-AMINOPROPYL DIMETHICONEHAIR CONDITIONING

BIS-AMINOPROPYL/ETHOXY AMINOPROPYL DIMETHICONEHAIR CONDITIONING

BIS-AMMONIUMPROPYL DIGLYCOL DIPROPYNOATEHAIR CONDITIONING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How BIS-AMINOPROPYL DIGLYCOL appears in the CosIng inventory

The CosIng inventory lists BIS-AMINOPROPYL DIGLYCOL as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

BIS-AMINOPROPYL DIGLYCOL is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

BIS-AMINOPROPYL DIGLYCOL is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, BIS-AMINOPROPYL DIGLYCOL carries the following function designation(s):

HAIR CONDITIONING

CAS 4246-51-9 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for BIS-AMINOPROPYL DIGLYCOL

This page reproduces the CosIng inventory entry for BIS-AMINOPROPYL DIGLYCOL from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research BIS-AMINOPROPYL DIGLYCOL and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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