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InventoryRef 9520906/03/2018

N-PROLYL PALMITOYL TRIPEPTIDE-56 ACETATE

Glycine, N2-(1-oxohexadecyl)-N6-L-prolyl-L-lysyl-L-histidyl-, acetate

N-PROLYL PALMITOYL TRIPEPTIDE-56 ACETATE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

Chemical identity and properties

PubChem 2D chemical structure for CAS 1899049-18-3
CAS 1899049-18-3PubChem CID 154731582

N-Prolyl palmitoyl tripeptide-56 acetate

IUPAC name
acetic acid;2-[[(2S)-2-[[(2S)-2-(hexadecanoylamino)-6-[[(2S)-pyrrolidine-2-carbonyl]amino]hexanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]acetic acid
Molecular formula
C37H65N7O8
Molecular weight
736.0 g/mol
Exact mass
735.48946206 Da
Topological polar surface area
232.0 Ų
Hydrogen-bond donors
8
Hydrogen-bond acceptors
10
Covalent units
2
Defined stereocentres
3

Also known as

Pal tripeptide proline5YX5BR41EQGlycine, N2-(1-oxohexadecyl)-N6-L-prolyl-L-lysyl-L-histidyl-, acetate (1:1)Glycine, N2-(1-oxohexadecyl)-N6-L-prolyl-L-lysyl-L-histidyl-, acetateRefChem:1092075UNII-5YX5BR41EQN-Prolyl palmitoyl tripeptide-56 acetate [INCI]EX-A10099

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

What the official INCI name states

The official label identifies a peptide- or protein-related cosmetic material.

Identity type from wording
peptide_or_protein

This structure is derived only from the official label wording. It does not establish composition, concentration, chemical equivalence, safety or regulatory permission.

Inventory details for N-PROLYL PALMITOYL TRIPEPTIDE-56 ACETATE

INCI name

N-PROLYL PALMITOYL TRIPEPTIDE-56 ACETATE

Description

Glycine, N2-(1-oxohexadecyl)-N6-L-prolyl-L-lysyl-L-histidyl-, acetate

Record provenance

Inventory reference
95209
Imported identity
N-PROLYL PALMITOYL TRIPEPTIDE-56 ACETATE
Source update
06/03/2018
European Commission CosIng source notes

Key data

EC
—
Restriction
—
Function
SKIN CONDITIONING
Maintaining the skin in good condition.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

Ingredients with overlapping formulation functions

Additional official and scientific sources

11 external databases to check this identity in

How N-PROLYL PALMITOYL TRIPEPTIDE-56 ACETATE appears in the CosIng inventory

The CosIng inventory lists N-PROLYL PALMITOYL TRIPEPTIDE-56 ACETATE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

N-PROLYL PALMITOYL TRIPEPTIDE-56 ACETATE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

N-PROLYL PALMITOYL TRIPEPTIDE-56 ACETATE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, N-PROLYL PALMITOYL TRIPEPTIDE-56 ACETATE carries the following function designation(s):

CAS 1899049-18-3 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

Source note for N-PROLYL PALMITOYL TRIPEPTIDE-56 ACETATE

This page reproduces the CosIng inventory entry for N-PROLYL PALMITOYL TRIPEPTIDE-56 ACETATE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research N-PROLYL PALMITOYL TRIPEPTIDE-56 ACETATE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

Tools & next steps

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