NONOXYNOL-9
Nonoxynol-9 is the ethoxylated alkyl phenol that conforms generally to the formula: (structure) where n has an average value of 9.
NONOXYNOL-9 is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.
Regulatory evidence by market
No rule for this ingredient has been imported for any of the 13 markets tracked here.
That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.
Chemical identity and properties

Nonaethylene Glycol Nonylphenyl Ether
Tergitol NP-9 is a tergitol polymer consisting of nonylbenzene with a nine-membered poly(ethylene glycol) moiety attached at position 4. It has a role as a nonionic surfactant and a contraceptive drug. — ChEBI
- IUPAC name
- 2-[2-[2-[2-[2-[2-[2-[2-[2-(4-nonylphenoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
- Molecular formula
- C33H60O10
- Molecular weight
- 616.8 g/mol
- Exact mass
- 616.41864811 Da
- XLogP3
- 4.6
- Topological polar surface area
- 103.0 Ų
- Hydrogen-bond donors
- 1
- Hydrogen-bond acceptors
- 10
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
16 more reported names
External database identifiers
- ChEBI:CHEBI:53775
- ChEMBL:CHEMBL1410
- EPA DTXSID:DTXSID00858720
- PubMed:22696373
- PubMed:22592833
- PubMed:22536154
- PubMed:22494324
- PubMed:22486240
- PubMed:22467453
- PubMed:22429795
- PubMed:22375797
- PubMed:22359093
- PubMed:22347807
- PubMed:22346752
- PubMed:22310826
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Nonoxynol-1
The CIR Expert Panel concluded that the following 27 Nonoxynols listed below are safe in the present practices of use and concentration in cosmetics as described in this safety assessment, when formulated to be non-irritating..Nonoxynol-1... — Cosmetic Ingredient Review (CIR)
- IUPAC name
- 1-ethoxy-4-(7-methyloctyl)benzene
- Molecular formula
- C17H28O
- Molecular weight
- 248.4 g/mol
- Exact mass
- 248.214015512 Da
- XLogP3
- 6.6
- Topological polar surface area
- 9.2 Ų
- Hydrogen-bond donors
- 0
- Hydrogen-bond acceptors
- 1
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
16 more reported names
Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

4-Nonylphenol diethoxylate
The CIR Expert Panel concluded that the following 27 Nonoxynols listed below are safe in the present practices of use and concentration in cosmetics as described in this safety assessment, when formulated to be non-irritating..Nonoxynol-2... — Cosmetic Ingredient Review (CIR)
- IUPAC name
- 2-[2-(4-nonylphenoxy)ethoxy]ethanol
- Molecular formula
- C19H32O3
- Molecular weight
- 308.5 g/mol
- Exact mass
- 308.23514488 Da
- XLogP3
- 5.6
- Topological polar surface area
- 38.7 Ų
- Hydrogen-bond donors
- 1
- Hydrogen-bond acceptors
- 3
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
16 more reported names
External database identifiers
- ChEMBL:CHEMBL194034
- EPA DTXSID:DTXSID9058600
Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
Inventory details for NONOXYNOL-9
INCI name
NONOXYNOL-9
Description
Nonoxynol-9 is the ethoxylated alkyl phenol that conforms generally to the formula: (structure) where n has an average value of 9.
Record provenance
- Inventory reference
- 92920
- Imported identity
- NONOXYNOL-9
- Source update
- 04/03/2019
Annex records for NONOXYNOL-9
Key data
- SURFACTANT - CLEANSING
- Wetting body surfaces, emulsifying or solubilizing oils, and suspending soil (generally, such ingredients contribute to the foaming and lathering properties of cleansing products).
- SURFACTANT - EMULSIFYING
- Helping suspensions or dispersions of liquids in a second liquid by reducing the surface tension of the substances to be emulsified.
Official EU ingredient-name evidence
The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.
Related inventory evidence
Ingredients with overlapping formulation functions
Additional official and scientific sources
11 external databases to check this identity in
Each link searches that source for this identity. What each source is, and its legal weight
How NONOXYNOL-9 appears in the CosIng inventory
The CosIng inventory lists NONOXYNOL-9 as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.
NONOXYNOL-9 is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.
Frequently asked questions
Source note for NONOXYNOL-9
This page reproduces the CosIng inventory entry for NONOXYNOL-9 from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.
Use this inventory page to research NONOXYNOL-9 and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.
Tools & next steps
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