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CAS 404830-45-1 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

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InventoryRef 9228508/10/2014

KETOTRAVOPROST

5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E)-3-oxo-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]cyclopentyl]-, 1-methylethyl ester

KETOTRAVOPROST is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 404830-45-1

CAS 404830-45-1PubChem CID 10207075

15-Keto travoprost

15-keto Fluprostenol isopropyl ester is a prostanoid. — ChEBI

IUPAC name: propan-2-yl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E)-3-oxo-4-[3-(trifluoromethyl)phenoxy]but-1-enyl]cyclopentyl]hept-5-enoate

Molecular formula: C26H33F3O6
Molecular weight: 498.5 g/mol
Exact mass: 498.22292325 Da
XLogP3: 4.4
Topological polar surface area: 93.1 Å²
Hydrogen-bond donors: 2
Hydrogen-bond acceptors: 9
Covalent units: 1
Defined stereocentres: 4

Also known as

15-Oxo travoprost(Z)-Isopropyl 7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((E)-3-oxo-4-(3-(trifluoromethyl)phenoxy)but-1-en-1-yl)cyclopentyl)hept-5-enoateUNII-4U2P9U9Z664U2P9U9Z66(5Z,13E)-(9S,11R)-9,11,-Dihydroxy-15-oxo-16-(m-trifluoromethylphenoxy)-17,18,19,20-tetranor-5,13-prostadienoic acid, isopropyl ester5-Heptenoic acid, 7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((1E)-3-oxo-4-(3-(trifluoromethyl)phenoxy)-1-buten-1-yl)cyclopentyl)-, 1-methylethyl ester, (5Z)-Travoprost impurity, 15-keto derivative-(USP)Travoprost impurity, 15-keto derivative-[USP]

16 more reported names

TRAVOPROST IMPURITY, 15-KETO DERIVATIVE-(USP IMPURITY)TRAVOPROST IMPURITY, 15-KETO DERIVATIVE-[USP IMPURITY]RefChem:19714715-keto Fluprostenol isopropyl esterTravoprost impurity, 15-keto derivative- [USP]Travoprost 15-Keto DerivativeCHEBI:168868HMS3648H2015-Ketofluprostenol isopropyl esterAC-38150DA-49110HY-116617CS-0066079SR-01000946510SR-01000946510-1TRAVOPROST IMPURITY, 15-KETO DERIVATIVE- [USP IMPURITY]

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:168868
EPA DTXSID:DTXSID001369114

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for KETOTRAVOPROST

INCI name

KETOTRAVOPROST

Description

5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E)-3-oxo-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]cyclopentyl]-, 1-methylethyl ester

Record provenance

Inventory reference: 92285
Imported identity: KETOTRAVOPROST
Source update: 08/10/2014

European Commission CosIng source notes

Annex records for KETOTRAVOPROST

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Key data

CAS

404830-45-1

—

Restriction

—

Function

HAIR CONDITIONING: Enhancing the appearance and feel of hair. Leaving the hair easy to comb, supple, soft and shiny and/or imparting volume, lightness, gloss, texture, etc.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#14155 · KETOTRAVOPROST

Ingredients with overlapping formulation functions

KAVALACTONESANTIOXIDANT; HAIR CONDITIONING; HUMECTANT; SKIN PROTECTING

KELP SULFATED OLIGOSACCHARIDESHAIR CONDITIONING

KERATINHAIR CONDITIONING, SKIN CONDITIONING

KERATIN AMINO ACIDSANTISTATIC, HAIR CONDITIONING, SKIN CONDITIONING

KIRENOLANTIMICROBIAL; ANTIOXIDANT; SKIN CONDITIONING - EMOLLIENT; HAIR CONDITIONING

KLUYVEROMYCES/LACTOBACILLUS/ABIES GRANDIS LEAF OIL FERMENT FILTRATEANTIMICROBIAL, ANTIOXIDANT, BLEACHING, HAIR CONDITIONING, SKIN CONDITIONING

KLUYVEROMYCES/LACTOBACILLUS/ADANSONIA DIGITATA SEED OIL/CALOPHYLLUM INOPHYLLUM …ANTIOXIDANT, ASTRINGENT, HAIR CONDITIONING, SKIN CONDITIONING

KLUYVEROMYCES/LACTOBACILLUS/ARTEMISIA PRINCEPS LEAF OIL FERMENT FILTRATEANTIMICROBIAL, ANTIOXIDANT, ASTRINGENT, BLEACHING, FRAGRANCE, HAIR CONDITIONING, SKIN CONDITIONING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How KETOTRAVOPROST appears in the CosIng inventory

The CosIng inventory lists KETOTRAVOPROST as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

KETOTRAVOPROST is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

KETOTRAVOPROST is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, KETOTRAVOPROST carries the following function designation(s):

HAIR CONDITIONING

CAS 404830-45-1 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for KETOTRAVOPROST

This page reproduces the CosIng inventory entry for KETOTRAVOPROST from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research KETOTRAVOPROST and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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