Is NITROFURAZONE safe to use in EU cosmetics?

NITROFURAZONE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Always verify against the current official CosIng database before formulating.

What other records share CAS 59-87-0?

CAS 59-87-0 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains NITROFURAZONE?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 9193329/10/2014

NITROFURAZONE

Nitrofurone

NITROFURAZONE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 59-87-0

CAS 59-87-0PubChem CID 5447130

Nitrofurazone

Nitrofurazone is a semicarbazone resulting from the formal condensation of semicarbazide with 5-nitrofuraldehyde. A broad spectrum antibacterial drug, although with little activity against Pseudomonas species, it is used as a local application for burns, ulcers, wounds and skin infections. It has a role as an antibacterial drug. It is a semicarbazone and a nitrofuran antibiotic. — ChEBI

IUPAC name: [(E)-(5-nitrofuran-2-yl)methylideneamino]urea

Molecular formula: C6H6N4O4
Molecular weight: 198.14 g/mol
Exact mass: 198.03890469 Da
XLogP3: 0.2
Topological polar surface area: 126.0 Å²
Hydrogen-bond donors: 2
Hydrogen-bond acceptors: 5
Covalent units: 1
Defined stereocentres: 0

Also known as

NitrofuralFuracinFuracilinAldomycinFuracillinFuracineNifuzonChemofuran

16 more reported names

FuracinettenFuracoccidFuraplast5-Nitro-2-furaldehyde semicarbazoneFuraldonFuresolActin-NMammexNefcoNitrofurazanBabrocidCoxistatFuracyclineFurazilineFurazoneMastofuran

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:44368
ChEMBL:CHEMBL869
PubMed:34839952
PubMed:33352258
PubMed:32418910
PubMed:29594315
PubMed:19017535
PubMed:18440737
PubMed:18222664
PubMed:15945272
PubMed:15488632
PubMed:11992141
PubMed:11548123
PubMed:11354658

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for NITROFURAZONE

INCI name

NITROFURAZONE

Description

Nitrofurone

Record provenance

Inventory reference: 91933
Imported identity: NITROFURAZONE
Source update: 29/10/2014

European Commission CosIng source notes

Annex records for NITROFURAZONE

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Key data

CAS

59-87-0

200-443-1

Restriction

—

Function

ANTIMICROBIAL: Preventing and/or slowing down microbial growth.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#17478 · NITROFURAZONE

Ingredients with overlapping formulation functions

NICOTIANA BENTHAMIANA R-(S-SOLITARY BEE OLIGOPEPTIDE-1 PENTAPEPTIDE-75 S-PROPIO…ANTIMICROBIAL; SKIN PROTECTING; LYTIC

NICOTINALDEHYDEANTIMICROBIAL

NIOBIUM PENTOXIDEANTI-SEBORRHEIC; ANTIMICROBIAL; ANTI-SEBUM; DEODORANT; ORAL CARE; OXIDISING

NISINANTIMICROBIAL

NOBILETINANTIMICROBIAL, ANTIOXIDANT, PRESERVATIVE

NONAPEPTIDE-42 AMIDEANTIMICROBIAL

NONOXYNOL-12 IODINEANTIMICROBIAL

NONOXYNOL-9 IODINEANTIMICROBIAL

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How NITROFURAZONE appears in the CosIng inventory

The CosIng inventory lists NITROFURAZONE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

NITROFURAZONE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

NITROFURAZONE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, NITROFURAZONE carries the following function designation(s):

ANTIMICROBIAL

CAS 59-87-0 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for NITROFURAZONE

This page reproduces the CosIng inventory entry for NITROFURAZONE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research NITROFURAZONE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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